KEGG   Theropithecus gelada (gelada): 112610028
Entry
112610028         CDS       T08041                                 
Symbol
PLD2
Name
(RefSeq) phospholipase D2 isoform X1
  KO
K01115  phospholipase D1/2 [EC:3.1.4.4]
Organism
tge  Theropithecus gelada (gelada)
Pathway
tge00564  Glycerophospholipid metabolism
tge00565  Ether lipid metabolism
tge01100  Metabolic pathways
tge04014  Ras signaling pathway
tge04024  cAMP signaling pathway
tge04071  Sphingolipid signaling pathway
tge04072  Phospholipase D signaling pathway
tge04144  Endocytosis
tge04666  Fc gamma R-mediated phagocytosis
tge04724  Glutamatergic synapse
tge04912  GnRH signaling pathway
tge04928  Parathyroid hormone synthesis, secretion and action
tge05200  Pathways in cancer
tge05208  Chemical carcinogenesis - reactive oxygen species
tge05212  Pancreatic cancer
tge05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:tge00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    112610028 (PLD2)
   00565 Ether lipid metabolism
    112610028 (PLD2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    112610028 (PLD2)
   04072 Phospholipase D signaling pathway
    112610028 (PLD2)
   04071 Sphingolipid signaling pathway
    112610028 (PLD2)
   04024 cAMP signaling pathway
    112610028 (PLD2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    112610028 (PLD2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    112610028 (PLD2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    112610028 (PLD2)
   04928 Parathyroid hormone synthesis, secretion and action
    112610028 (PLD2)
  09156 Nervous system
   04724 Glutamatergic synapse
    112610028 (PLD2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112610028 (PLD2)
   05208 Chemical carcinogenesis - reactive oxygen species
    112610028 (PLD2)
   05231 Choline metabolism in cancer
    112610028 (PLD2)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    112610028 (PLD2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tge04131]
    112610028 (PLD2)
Enzymes [BR:tge01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.4  phospholipase D
     112610028 (PLD2)
Membrane trafficking [BR:tge04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    112610028 (PLD2)
 Endosome - Golgi transport
  Others
   Others
    112610028 (PLD2)
SSDB
Motif
Pfam: PLDc PX PLDc_2 PH PH_2
Other DBs
NCBI-GeneID: 112610028
NCBI-ProteinID: XP_025219079
Ensembl: ENSTGEG00000019061
UniProt: A0A8D2FMM8
LinkDB
Position
16:61090077..61105543
AA seq 933 aa
MMVTPESLFPTGDELDSSQLQMESDEVDTLREGEDPADRMHPFLAIYELQPLKVHPLVFA
PGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLLRHKVL
MSLLPLARFAVAYSPAQDAANREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYR
NYHALTEFLEVSQLSFIPDLGCKGLEGTIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVV
KDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARYGVRIDTSHRSLILKCSSYRQAR
WWAQEITELARGPGRDFLQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIF
ITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRAL
MLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSE
SAASQPPTLCPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPW
RDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQ
CTTVQVLRSVDRWSAGTLENSILNAYLHTIKESRHFLYIENQFFISCSDGRTVLNKVGDE
IVDRILKAHKQGQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHR
LKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKMLIADDRTVIIGSANINDRSLL
GKRDSELAVLIEDTETEPSLMNGVEYQAGRFALSLRKHCFSVILGANTRPDLDLRDPVCD
DFFQLWQDTAESNANIYEQIFRCLPTNATRSLRTLREYVAVEPLATVSPPLARSELTQVQ
GHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT
NT seq 2802 nt   +upstreamnt  +downstreamnt
atgatggtgacccctgagagcctcttccccactggggacgaactggactccagccagctc
cagatggagtccgatgaggtggacactctgagggagggagaggacccagccgaccggatg
cacccgtttctggccatctatgagcttcagcctctgaaagtgcaccccttggtgttcgca
cctggggtccctgtcacagcccaggtggtgggcaccgaaagatacaccagcggatccaag
gtaggaacctgcactctgtattctgtccgcttgactcacggcgactttacctggacaacc
aagaagaagttccgtcattttcaggagctgcatcgggacctcctgagacacaaagtcttg
atgagcctgctccctctggctcgttttgccgttgcctattctccagcccaagatgcagcc
aaccgagagatgccctctctaccccgggcaggtcctgagggctccaccagacacgcagcc
agcaaacagaaatacctggagaattacctcaaccgcctcttgaccatgtctttctatcgc
aactaccatgccttgacagaattcctggaagtcagtcagctgtcctttatcccagacctg
ggctgcaaagggctggaggggacgatccggaagcgctcaggtggccaccgcgttcctggc
ctcacctgctgtggccgagaccaagtttgttatcgctggtccaagaggtggctggtggtg
aaggactccttcctgctgtacatgtgcctcgagacgggtgccatctcatttgttcagctc
tttgaccctggctttgaggtgcaggtggggaaaaggagcacggaggcacggtacggcgtg
cggatcgacacctcccacaggtccttgattctcaagtgcagcagctaccggcaggcacgg
tggtgggcccaagagatcactgagctggcgcggggcccaggcagagacttcctacagctg
caccagcatgacagctacgccccaccccggcctgggaccttggcccggtggtttgtgaat
ggggcaggttactttgctgctgtggcagatgccatccttcgagctcaagaggagattttc
atcacagactggtggttgagtcctgaggtttacctgaagcgtccggcccattcagatgac
tggagactggacattatgctcaagaggaaggcggaggagggtgtccgcgtgtccattctg
ctgtttaaggaagtggaattggccttgggcatcaacagtggctatagcaagagggcactg
atgctgctgcaccccaacataaaggtgatgcgtcacccagaccaagtgacgctgtgggcc
catcatgagaagctcctggtggtggaccaagtggtagcattcctggggggactggacctt
gcctatggccgctgggatgacctgcactaccgactgactgaccttggagactcctctgaa
tcagctgcctcccagcctcccaccctgtgcccagactcgccggccaccccagacctctct
cacaaccaattcttctggctgggcaaggactacagcaatcttatcaccaaggactgggtg
cagctcgaccggcctttcgaagatttcattgacagggagacgacccctcggatgccatgg
cgggacgttggggtggtcgtccacggcctacctgcccgggacctcgcccggcacttcatc
cagcgctggaacttcaccaagaccaccaaggccaagtacaagactcccacgtacccctac
ctgcttcccaagtctaccagcactgccaaccagctccccttcacgctcccaggggggcag
tgcaccactgtgcaggtcttgcggtcagtggaccgctggtcagcagggactctggagaac
tccatcctcaatgcctacctccacaccatcaaggagagccggcacttcctctacattgag
aatcagttcttcattagctgctcagatgggcggacggttctgaacaaggtgggcgatgag
attgtggacagaatcctgaaggcccacaaacaggggcagtgtttccgagtctacgtgctt
ttgcccttactccctggcttcgagggtgatatctccacgggtggtggcaactccattcag
gccattctgcattttacttacaggaccctgtgtcgtggggagtattcaatcctgcatcgc
ctcaaagcagccatggggacagcatggcgggactatatttccatctgcgggcttcgtaca
cacggagagctgggcgggcaccccgtctcggagctcatctacatccacagcaagatgctc
atcgcagatgaccggacagtcatcattggttctgcaaacatcaatgaccggagcttgctg
gggaagcgggacagtgagctggccgtgctgatcgaggacacagagacagaaccatccctc
atgaatggggtggagtatcaggcgggcaggtttgccttgagtctgcggaagcactgcttc
agtgtgattcttggagcaaatacccggccagacttggatctccgagaccccgtctgtgat
gacttcttccagttgtggcaagacacagctgagagcaacgctaacatctatgagcagatc
ttccgctgcctaccgaccaatgccacacgttccctgcggacactccgggagtatgtggcc
gtggagcccttggccaccgtcagtcctcccttggctcggtctgagctcacccaggtccag
ggccacctggtccacttccccctcaagttccttgaggatgagtctttgttgcccccgctg
ggtagcaaggagggcatgatccccctagaagtgtggacatag

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