Theropithecus gelada (gelada): 112612090
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Entry
112612090 CDS
T08041
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00230
Purine metabolism
tge01100
Metabolic pathways
tge04024
cAMP signaling pathway
tge04928
Parathyroid hormone synthesis, secretion and action
tge05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112612090 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
112612090 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
112612090 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
112612090 (PDE4A)
Enzymes [BR:
tge01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
112612090 (PDE4A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
112612090
NCBI-ProteinID:
XP_025221944
Ensembl:
ENSTGEG00000024959
LinkDB
All DBs
Position
19:10191512..10247240
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AA seq
886 aa
AA seq
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MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPPPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPVPTNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPHPPDKFQFELTLEEEEEEE
ISMAPIPCTAQEALTAQGLSGAEEALDTTMAREASPAQESLDVMAQDESLEAELEEVYLT
QQAQSTGSAPVAQDEFSSQEESVVAVSQSSPSALALQSPLLPAWRTLSVSEHAPGLPGLP
STAAEVEAQREHQAAKRACSACTGTSGEDTSALPAPGGGGSGGDPT
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccgaccgtcccctcggaaaggagcctgtctctgtcactgcccgggccccgg
gagggccaagccaccctgaagcctccccctcagcacctgtggcggcagcctcggaccccc
atccgtatccagcagcgcggctactccgacagcgcggagcgcgcagagccggagcggccg
cctcaccggcccatagagcgcgccgatgccatggacaccagcgaccggcccggcctgcgc
acgacccgcatgtcctggccctcgtccttccatggcactggcaccggcagcggcggcgcg
ggcggaggcagcagcaggcgcttcgaggcagagaatgggccgacaccacctcctggccgc
agccccctggactcgcaggcgagcccaggactcgtgctacatgccggggcggccaccagc
cagcgccgggagtccttcttgtaccgctcggacagcgactatgacatgtcacccaagacc
atgtcccggaactcatcggtcaccagcgaggcgcacgctgaagacctcatcgtaacaccg
tttgctcaggtgctggccagcctccggagcgtccgtagcaacttctcactcctgaccaat
gtgcccgttcccactaacaagcggtccccgctgggcggccccacccctgtctgcaaggcc
acgctgtcagaagaaacgtgtcagcagttggcccgggagacgctggaagagctggactgg
tgtctggagcagctggagaccatgcaaacttaccgctctgtcagcgagatggcctcgcac
aagttcaagaggatgttgaaccgtgaactcacacacctgtcagaaatgagcaggtcggga
aaccaggtctcagagtacatttccacaacattcctggacaaacagaatgaagtggagatc
ccgtcacccacgatgaaggaacgagaaaaacagcaagcgccgcgaccaagaccgtcccag
ccgcccccgccccctgtaccacacttacagcccatgtcccaaatcacaggggtgaaaaag
ttgatgcatagtaacagcctgaacaactctaacattccccgatttggggtgaagaccgat
caagaagagctcctggcccaagaactggagaacctgaacaagtggggcctaaacatcttt
tgcgtgtcagattacgccggaggccgctcgctcacctgcatcatgtacatgatattccag
gagcgggacctgctgaagaaattccgcatccctgtggacacgatggtgacatacatgctg
acgctggaggatcactaccacgctgacgtagcctaccataacagcctgcacgctgccgac
gtactgcagtccacccacgtactgctggccacgcctgcgctagatgcagtgttcacggac
ctggagattctcgccgccctcttcgcggctgccatacacgatgtagatcaccctggggtc
tccaaccagttcctcatcaacaccaattcggagctggcgctcatgtacaacgatgagtcg
gtgctcgagaatcaccacctggccgtgggcttcaagctgctgcaggaggacaactgcgac
atcttccagaacctcagcaagcgccagcggcagagcctacgcaagatggtcatcgacatg
gtgctggccacggacatgtccaagcacatgaccctcctggctgacctgaagaccatggtg
gagaccaagaaagtgaccagctcgggggtcctgctgctggataactactccgaccgcatc
caggtcctccggaacatggtgcattgcgcagacctcagcaaccccaccaagccgctggag
ctgtaccgccagtggacggaccgcatcatggccgagttcttccagcagggtgaccgtgag
cgcgagcgtggcatggaaatcagccccatgtgtgacaagcacactgcctccgtggagaag
tctcaggtgggttttattgactacattgtacacccattgtgggagacctgggcagacctt
gtccacccagacgcccaggagatcctggacactttggaggacaaccgggactggtactac
agcgccatccggcagagcccgtcgccgccacctgaggaggagtcaagggggccaggtcac
ccacacccacctgataagttccagtttgagctgactctggaggaggaagaagaggaagaa
atatcaatggccccgataccgtgcacagcccaagaggcattgacagcgcagggattgtca
ggagccgaggaagctctggatacaaccatggcccgggaggcatccccagcgcaggagtca
ttggatgttatggcacaggatgagtccctggaggccgagctggaggaagtatatttgaca
cagcaggcacagtccacaggcagtgcacctgtggctcaggatgagttctcgtcccaggaa
gaatccgtggttgctgtaagccagagcagcccctccgccctggctcttcaaagccccctt
ctccctgcctggaggaccctgtctgtttcagagcatgccccgggcctcccgggcctcccc
tccacggcggccgaggtggaggcccaacgagagcaccaggctgccaagagggcttgcagt
gcctgcacagggacatctggggaggacacatctgcactcccagctcctggtgggggaggg
tcaggtggagaccctacctga
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