Theropithecus gelada (gelada): 112612156
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Entry
112612156 CDS
T08041
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00280
Valine, leucine and isoleucine degradation
tge00640
Propanoate metabolism
tge00785
Lipoic acid metabolism
tge01100
Metabolic pathways
tge01210
2-Oxocarboxylic acid metabolism
Module
tge_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
112612156 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
112612156 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
112612156 (BCKDHA)
Enzymes [BR:
tge01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
112612156 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
112612156
NCBI-ProteinID:
XP_025222086
Ensembl:
ENSTGEG00000022636
UniProt:
A0A8D2K6K7
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All DBs
Position
19:complement(38606452..38636939)
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AA seq
445 aa
AA seq
DB search
MAVAIAAARVWRPNRGLSQAALLLLWRPGARGLARSHPRRQQQQFSSLDDKPQFPGASAE
FIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILY
ESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYG
NISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGA
ASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDG
NDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHP
ISRLRHYLLSQGWWDEEQEKAWRKQSRKKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQL
RKQQESLARHLQTYGEHYPLEHFDK
NT seq
1338 nt
NT seq
+upstream
nt +downstream
nt
atggcggtagcgatcgctgcagcgagggtctggcggccaaaccgaggcctgagccaggct
gccctcttgctgctgtggcggcctggggctcggggactggctagatctcacccgcgcagg
cagcagcagcagttctcatctctggatgacaagccccagttcccaggggcctcggctgag
tttatagacaagttggaattcatccagcccaatgttatctctggaatccccatctaccgt
gtcatggaccggcaaggccagatcatcaaccccagcgaggacccccatctgccaaaggag
aaggtgctgaagctctacaagagcatgacactgcttaacaccatggaccgcatcctctat
gagtctcagcggcagggccggatctccttctacatgaccaactatggcgaggagggcacg
cacgtggggagtgccgccgccctggacaacacagacctggtgtttggccagtaccgggag
gcaggtgtgctgatgtatcgcgactaccccctggaactattcatggcccagtgctatggc
aacatcagtgacttgggcaaggggcgccagatgcctgtccactacggctgcaaggaacgc
cacttcgtcactatctcctctccactggccacacagatccctcaggcggtgggggcagcc
tacgcagccaagcgggccaatgccaacagggtcgtcatctgttacttcggtgagggggca
gccagcgagggggatgcccacgccggcttcaacttcgcggccacacttgagtgccccatc
atcttcttctgccggaacaatggctacgccatctccacgcccacctccgagcagtatcgc
ggcgatggcatcgcggcacgaggccccgggtatggcatcatgtcaatccgtgtggatggt
aatgatgtgtttgctgtgtacaatgccacaaaggaggcccgacggcgcgctgtggcagag
aaccagcccttcctcatcgaggccatgacctacaggatcgggcaccacagcaccagtgac
gacagttcggcgtaccgctcggtggacgaagtcaattactgggacaagcaggaccacccc
atctcccggctgcggcactacctgctgagccaaggctggtgggatgaggagcaggagaag
gcctggaggaagcagtcccgcaagaaggtgatggaggcctttgagcaggcagagcggaag
cccaaacccaaccccaacctgctcttctcagatgtgtatcaggagatgcccgcccagctc
cgcaagcagcaggagtccctggcccgccacctgcagacctacggggagcactacccactg
gagcactttgataagtga
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