Theropithecus gelada (gelada): 112615463
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Entry
112615463 CDS
T08041
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00010
Glycolysis / Gluconeogenesis
tge00020
Citrate cycle (TCA cycle)
tge00620
Pyruvate metabolism
tge00785
Lipoic acid metabolism
tge01100
Metabolic pathways
tge01200
Carbon metabolism
tge01210
2-Oxocarboxylic acid metabolism
tge04066
HIF-1 signaling pathway
tge04922
Glucagon signaling pathway
tge05230
Central carbon metabolism in cancer
tge05415
Diabetic cardiomyopathy
Module
tge_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
112615463 (PDHA1)
00020 Citrate cycle (TCA cycle)
112615463 (PDHA1)
00620 Pyruvate metabolism
112615463 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
112615463 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
112615463 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
112615463 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
112615463 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
112615463 (PDHA1)
Enzymes [BR:
tge01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
112615463 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
112615463
NCBI-ProteinID:
XP_025227935
Ensembl:
ENSTGEG00000020315
LinkDB
All DBs
Position
X:41082831..41099185
Genome browser
AA seq
433 aa
AA seq
DB search
MTLSRRAATEAWRLLGHLKETLGHPRRASWAVRSRRCRQCLYFMRKMLAAVSRVLSGASQ
KPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELK
ADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAE
LTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDG
AANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGM
DILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPI
MLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEV
RGANQWIKFKSVS
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgactctgtcacgtcgcgctgcgactgaggcgtggcgtctgctggggcacctgaaggag
actttgggacaccctcgtcgtgcctcttgggctgtgaggagtcgccgctgccgccagtgc
ctgtacttcatgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcag
aaaccggcaagcagagtgctggtagcatcccgtaattttgcaaatgatgctacatttgaa
attaagaaatgtgaccttcaccgactggaagaaggccctcctgtcacaacagtgctcacc
agggaggatgggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaa
gcagatcagctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcag
gaagcttgctgtgtgggcctggaagccggcatcaaccccacagaccatctcataacagcc
taccgggctcacggctttaccttcacccggggcctttccgtccgagaaattctcgcagag
cttacaggacgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgcc
aagaacttctacgggggcaatggcatcgtgggagcgcaggtgcccctgggcgctgggatt
gctctagcctgtaagtataatggaaaagatgaggtctgcctgactttatatggcgatggt
gctgctaaccagggccagatatttgaagcttacaacatggcagctttgtggaaattacct
tgtattttcatctgtgagaataatcgctatggaatgggaacatctgttgagagagcagca
gccagcactgattactacaagagaggcgatttcattcctgggctgagagtggatggaatg
gatatcctgtgcgtccgagaggcgacaaggtttgctgctgcctattgtagatctgggaag
gggcccatcctgatggagctgcagacttatcgttaccacggacacagtatgagtgatcct
ggagtcagttaccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctatt
atgcttctcaaggacaggatggtgaacagcaatcttgccagtgtggaagaactaaaggaa
attgatgtggaagtgaggaaggagattgaggatgctgcccagtttgccaccgccgatcct
gagccacctttggaggagctgggctaccacatctactccagcgacccacctttcgaagtt
cgtggtgccaatcagtggatcaagtttaagtcagtcagttaa
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