KEGG   Theropithecus gelada (gelada): 112619416
Entry
112619416         CDS       T08041                                 
Symbol
NRAS
Name
(RefSeq) GTPase NRas isoform X1
  KO
K07828  GTPase NRas
Organism
tge  Theropithecus gelada (gelada)
Pathway
tge01521  EGFR tyrosine kinase inhibitor resistance
tge01522  Endocrine resistance
tge04010  MAPK signaling pathway
tge04012  ErbB signaling pathway
tge04014  Ras signaling pathway
tge04015  Rap1 signaling pathway
tge04062  Chemokine signaling pathway
tge04068  FoxO signaling pathway
tge04071  Sphingolipid signaling pathway
tge04072  Phospholipase D signaling pathway
tge04137  Mitophagy - animal
tge04140  Autophagy - animal
tge04150  mTOR signaling pathway
tge04151  PI3K-Akt signaling pathway
tge04210  Apoptosis
tge04211  Longevity regulating pathway
tge04213  Longevity regulating pathway - multiple species
tge04218  Cellular senescence
tge04360  Axon guidance
tge04370  VEGF signaling pathway
tge04371  Apelin signaling pathway
tge04540  Gap junction
tge04550  Signaling pathways regulating pluripotency of stem cells
tge04625  C-type lectin receptor signaling pathway
tge04650  Natural killer cell mediated cytotoxicity
tge04660  T cell receptor signaling pathway
tge04662  B cell receptor signaling pathway
tge04664  Fc epsilon RI signaling pathway
tge04714  Thermogenesis
tge04720  Long-term potentiation
tge04722  Neurotrophin signaling pathway
tge04725  Cholinergic synapse
tge04726  Serotonergic synapse
tge04730  Long-term depression
tge04810  Regulation of actin cytoskeleton
tge04910  Insulin signaling pathway
tge04912  GnRH signaling pathway
tge04915  Estrogen signaling pathway
tge04916  Melanogenesis
tge04917  Prolactin signaling pathway
tge04919  Thyroid hormone signaling pathway
tge04921  Oxytocin signaling pathway
tge04926  Relaxin signaling pathway
tge04929  GnRH secretion
tge04933  AGE-RAGE signaling pathway in diabetic complications
tge04935  Growth hormone synthesis, secretion and action
tge05010  Alzheimer disease
tge05022  Pathways of neurodegeneration - multiple diseases
tge05034  Alcoholism
tge05160  Hepatitis C
tge05161  Hepatitis B
tge05163  Human cytomegalovirus infection
tge05165  Human papillomavirus infection
tge05166  Human T-cell leukemia virus 1 infection
tge05167  Kaposi sarcoma-associated herpesvirus infection
tge05170  Human immunodeficiency virus 1 infection
tge05200  Pathways in cancer
tge05203  Viral carcinogenesis
tge05205  Proteoglycans in cancer
tge05206  MicroRNAs in cancer
tge05207  Chemical carcinogenesis - receptor activation
tge05208  Chemical carcinogenesis - reactive oxygen species
tge05210  Colorectal cancer
tge05211  Renal cell carcinoma
tge05213  Endometrial cancer
tge05214  Glioma
tge05215  Prostate cancer
tge05216  Thyroid cancer
tge05218  Melanoma
tge05219  Bladder cancer
tge05220  Chronic myeloid leukemia
tge05221  Acute myeloid leukemia
tge05223  Non-small cell lung cancer
tge05224  Breast cancer
tge05225  Hepatocellular carcinoma
tge05226  Gastric cancer
tge05230  Central carbon metabolism in cancer
tge05231  Choline metabolism in cancer
tge05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tge05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112619416 (NRAS)
   04012 ErbB signaling pathway
    112619416 (NRAS)
   04014 Ras signaling pathway
    112619416 (NRAS)
   04015 Rap1 signaling pathway
    112619416 (NRAS)
   04370 VEGF signaling pathway
    112619416 (NRAS)
   04371 Apelin signaling pathway
    112619416 (NRAS)
   04068 FoxO signaling pathway
    112619416 (NRAS)
   04072 Phospholipase D signaling pathway
    112619416 (NRAS)
   04071 Sphingolipid signaling pathway
    112619416 (NRAS)
   04151 PI3K-Akt signaling pathway
    112619416 (NRAS)
   04150 mTOR signaling pathway
    112619416 (NRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112619416 (NRAS)
   04137 Mitophagy - animal
    112619416 (NRAS)
  09143 Cell growth and death
   04210 Apoptosis
    112619416 (NRAS)
   04218 Cellular senescence
    112619416 (NRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    112619416 (NRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    112619416 (NRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112619416 (NRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    112619416 (NRAS)
   04650 Natural killer cell mediated cytotoxicity
    112619416 (NRAS)
   04660 T cell receptor signaling pathway
    112619416 (NRAS)
   04662 B cell receptor signaling pathway
    112619416 (NRAS)
   04664 Fc epsilon RI signaling pathway
    112619416 (NRAS)
   04062 Chemokine signaling pathway
    112619416 (NRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112619416 (NRAS)
   04929 GnRH secretion
    112619416 (NRAS)
   04912 GnRH signaling pathway
    112619416 (NRAS)
   04915 Estrogen signaling pathway
    112619416 (NRAS)
   04917 Prolactin signaling pathway
    112619416 (NRAS)
   04921 Oxytocin signaling pathway
    112619416 (NRAS)
   04926 Relaxin signaling pathway
    112619416 (NRAS)
   04935 Growth hormone synthesis, secretion and action
    112619416 (NRAS)
   04919 Thyroid hormone signaling pathway
    112619416 (NRAS)
   04916 Melanogenesis
    112619416 (NRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    112619416 (NRAS)
   04726 Serotonergic synapse
    112619416 (NRAS)
   04720 Long-term potentiation
    112619416 (NRAS)
   04730 Long-term depression
    112619416 (NRAS)
   04722 Neurotrophin signaling pathway
    112619416 (NRAS)
  09158 Development and regeneration
   04360 Axon guidance
    112619416 (NRAS)
  09149 Aging
   04211 Longevity regulating pathway
    112619416 (NRAS)
   04213 Longevity regulating pathway - multiple species
    112619416 (NRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    112619416 (NRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112619416 (NRAS)
   05206 MicroRNAs in cancer
    112619416 (NRAS)
   05205 Proteoglycans in cancer
    112619416 (NRAS)
   05207 Chemical carcinogenesis - receptor activation
    112619416 (NRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    112619416 (NRAS)
   05203 Viral carcinogenesis
    112619416 (NRAS)
   05230 Central carbon metabolism in cancer
    112619416 (NRAS)
   05231 Choline metabolism in cancer
    112619416 (NRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112619416 (NRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112619416 (NRAS)
   05225 Hepatocellular carcinoma
    112619416 (NRAS)
   05226 Gastric cancer
    112619416 (NRAS)
   05214 Glioma
    112619416 (NRAS)
   05216 Thyroid cancer
    112619416 (NRAS)
   05221 Acute myeloid leukemia
    112619416 (NRAS)
   05220 Chronic myeloid leukemia
    112619416 (NRAS)
   05218 Melanoma
    112619416 (NRAS)
   05211 Renal cell carcinoma
    112619416 (NRAS)
   05219 Bladder cancer
    112619416 (NRAS)
   05215 Prostate cancer
    112619416 (NRAS)
   05213 Endometrial cancer
    112619416 (NRAS)
   05224 Breast cancer
    112619416 (NRAS)
   05223 Non-small cell lung cancer
    112619416 (NRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112619416 (NRAS)
   05170 Human immunodeficiency virus 1 infection
    112619416 (NRAS)
   05161 Hepatitis B
    112619416 (NRAS)
   05160 Hepatitis C
    112619416 (NRAS)
   05163 Human cytomegalovirus infection
    112619416 (NRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112619416 (NRAS)
   05165 Human papillomavirus infection
    112619416 (NRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112619416 (NRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    112619416 (NRAS)
  09165 Substance dependence
   05034 Alcoholism
    112619416 (NRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112619416 (NRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    112619416 (NRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112619416 (NRAS)
   01522 Endocrine resistance
    112619416 (NRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tge04131]
    112619416 (NRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tge04147]
    112619416 (NRAS)
   04031 GTP-binding proteins [BR:tge04031]
    112619416 (NRAS)
Membrane trafficking [BR:tge04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    112619416 (NRAS)
 Endocytosis
  Macropinocytosis
   Ras GTPases
    112619416 (NRAS)
Exosome [BR:tge04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   112619416 (NRAS)
  Exosomal proteins of other body fluids (saliva and urine)
   112619416 (NRAS)
  Exosomal proteins of breast cancer cells
   112619416 (NRAS)
  Exosomal proteins of colorectal cancer cells
   112619416 (NRAS)
GTP-binding proteins [BR:tge04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    112619416 (NRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Septin ATPase_2 Hpr_kinase_C Ldh_1_N
Other DBs
NCBI-GeneID: 112619416
NCBI-ProteinID: XP_025233173
Ensembl: ENSTGEG00000006042
LinkDB
Position
1:complement(6934266..6947334)
AA seq 222 aa
MAVPGSPTIFPAVVLNLSKAEAVELEVSSCWCEMTEYKLVVVGAGGVGKSALTIQLIQNH
FVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNS
KSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAK
TRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCMGLPCVVM
NT seq 669 nt   +upstreamnt  +downstreamnt
atggcggttccggggtctccaacaattttccctgctgtggtcctgaatctgtccaaagca
gaggcagtggagcttgaggtaagttcttgctggtgtgaaatgactgagtacaaactggtg
gtggttggagcaggtggtgttgggaaaagtgcactgacaatccagctaatccagaaccac
tttgtagatgaatatgatcccaccatagaggattcttacagaaaacaggtggttatagat
ggtgaaacctgtttgttggacatactggatacagctggacaagaagagtacagtgccatg
agagaccaatacatgaggacaggcgaaggcttcctctgtgtatttgccatcaataatagc
aagtcatttgcggatattaacctctacagggagcagattaagcgagtaaaagactcggat
gatgtacctatggtgctagtgggaaacaagtgtgatttgccaacaaggacagttgataca
aaacaagcccacgaactggccaagagttacgggattccattcattgaaacctcagccaag
accagacagggtgttgaagatgctttttacacactggtaagagaaatacgccagtaccga
atgaaaaaactcaacagcagtgatgatgggactcagggttgtatgggattaccatgtgtg
gtgatgtaa

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