Theropithecus gelada (gelada): 112620491
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Entry
112620491 CDS
T08041
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge01521
EGFR tyrosine kinase inhibitor resistance
tge04151
PI3K-Akt signaling pathway
tge04217
Necroptosis
tge04380
Osteoclast differentiation
tge04550
Signaling pathways regulating pluripotency of stem cells
tge04620
Toll-like receptor signaling pathway
tge04621
NOD-like receptor signaling pathway
tge04630
JAK-STAT signaling pathway
tge04658
Th1 and Th2 cell differentiation
tge04659
Th17 cell differentiation
tge05140
Leishmaniasis
tge05145
Toxoplasmosis
tge05152
Tuberculosis
tge05160
Hepatitis C
tge05161
Hepatitis B
tge05162
Measles
tge05163
Human cytomegalovirus infection
tge05164
Influenza A
tge05165
Human papillomavirus infection
tge05166
Human T-cell leukemia virus 1 infection
tge05167
Kaposi sarcoma-associated herpesvirus infection
tge05168
Herpes simplex virus 1 infection
tge05169
Epstein-Barr virus infection
tge05171
Coronavirus disease - COVID-19
tge05200
Pathways in cancer
tge05203
Viral carcinogenesis
tge05212
Pancreatic cancer
tge05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
112620491 (JAK1)
04151 PI3K-Akt signaling pathway
112620491 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
112620491 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
112620491 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
112620491 (JAK1)
04621 NOD-like receptor signaling pathway
112620491 (JAK1)
04658 Th1 and Th2 cell differentiation
112620491 (JAK1)
04659 Th17 cell differentiation
112620491 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
112620491 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112620491 (JAK1)
05203 Viral carcinogenesis
112620491 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
112620491 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
112620491 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
112620491 (JAK1)
05161 Hepatitis B
112620491 (JAK1)
05160 Hepatitis C
112620491 (JAK1)
05171 Coronavirus disease - COVID-19
112620491 (JAK1)
05164 Influenza A
112620491 (JAK1)
05162 Measles
112620491 (JAK1)
05168 Herpes simplex virus 1 infection
112620491 (JAK1)
05163 Human cytomegalovirus infection
112620491 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
112620491 (JAK1)
05169 Epstein-Barr virus infection
112620491 (JAK1)
05165 Human papillomavirus infection
112620491 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
112620491 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
112620491 (JAK1)
05140 Leishmaniasis
112620491 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112620491 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tge01001
]
112620491 (JAK1)
Enzymes [BR:
tge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
112620491 (JAK1)
Protein kinases [BR:
tge01001
]
Non-receptor tyrosine kinases
JAK family [OT]
112620491 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
112620491
NCBI-ProteinID:
XP_025234941
Ensembl:
ENSTGEG00000011995
UniProt:
A0A8D2F5V3
LinkDB
All DBs
Position
1:complement(92675884..92911180)
Genome browser
AA seq
1154 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEVPEPGVEVIFYMSDREPLRLGSGEYTAEEL
CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WFHSNDSGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEQGQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRIFKKDLVQGEHLGRGTRTHIYSG
TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
SFQNLIEGFEALLK
NT seq
3465 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagactgaggtgaacctggaggtccctgagccaggggtggaagtgatcttc
tatatgtcggacagggagcccctccggctgggcagtggagagtatacagcagaggaactg
tgcatcagggctgcacaggcatgccgtatctctcctctttgtcacaacctctttgcccta
tatgatgagaacaccaagctctggtatgctccaaatcgcaccatcaccgttgatgacaag
atgtccctccgactccactaccggatgaggttctatttcaccaattggcacggaaccaac
gacaatgagcagtcagtgtggcgtcattctccaaagaagcagaaaaatggctacgagaaa
aaaaaggttccagatgcaacccctctccttgatgccagctcactggagtatctgtttgct
cagggacagtatgatttggtgaaatgcctggctcccattcgagaccccaagaccgagcag
gatgggcatgatattgaaaacgagtgtctggggatggctgtcctggccatctcacactat
gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctacaagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata
aataatgttttcaaggatttcctaaaggaatttaacaacaagaccatttgtgacagcagc
gtgtccacgcatgacctgaaggtgaaatacttggctaccttggaaactttgacaaaacat
tatggcgctgaaatatttgagacttccatgttgctgatttcatcagaaaatgagatgaat
tggtttcattcgaatgacagtggaaatgttctgtactatgaagtgatggtgactgggaat
cttggaatccagtggaggcataaaccaaatgttgtttctgttgaaaaggaaaaaaataaa
ctgaagcggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaagatccgg
gaagagtggaacaatttttcttacttccctgaaatcactcacattgtaataaaggagtct
gtggtcagcattaacaagcaggacaacaagaaaatggaactgaagctctcttcccatgag
gaggccttgtcctttgtgtcactggtagatggctacttccggctcaccgcagacgcccat
cattacctctgcaccgacgtggcccccccgttgatcgtccacaacatacagaatggctgt
catggtccaatctgtacagaatatgccatcaataaattgcggcaagaaggaagcgaggag
gggatgtacgtgctgaggtggagctgcaccgactttgacaacatcctcatgaccgtcacc
tgctttgagaagtctgagcaggggcagggtgcccagaagcagttcaagaactttcagatc
gaggtgcagaagggccgctacagcctgcatggttcggaccgcagcttccccagcttggga
gacctcatgagccacctcaagaagcagatcctgcgcacggataacatcagcttcatgttg
aaacgctgctgccagcccaagccccgagaaatctccaacctgctggtggctactaagaaa
gcccaggagtggcagcccgtctaccccatgagccagttgagttttgatcggatcttcaag
aaggatctggtgcagggcgagcaccttgggagaggcacgagaacacacatctactctggg
accctgatggattacaaggatgacgaaggaacttccgaagagaagaagataaaagtgatc
ctcaaagtcttagaccccagccacagggatatttccctggccttcttcgaggcagccagc
atgatgagacaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtccgcgac
gtggagaatatcatggtggaagagtttgtggaagggggtcctctggatctcttcatgcac
cggaaaagcgatgtccttactacaccctggaaattcaaagttgccaaacagctggccagt
gccctgagctacttggaagataaagacctggtccatggaaatgtgtgtactaaaaacctc
ctcctggcccgtgagggcatcgacagcgagtgtggtccgttcatcaagctcagtgaccct
ggcatccccattacggtgctgtctaggcaagagtgcattgaacgaatcccgtggattgct
cccgagtgtgttgaggactccaagaacctgagtgtggctgctgacaagtggagctttgga
actacgctctgggaaatctgctacaatggcgagatccccttgaaagacaagacactgatt
gagaaagagagattctatgaaagccggtgcaggccagtgacaccatcatgtaaggagctg
gctgacctcatgacccgctgcatgaactacgaccccaatcagaggcccttctttcgagcc
atcatgagagacattaataagcttgaagagcagaatccagatattgtttcagaaaaaaag
ccagcaactgaagtggaccccacgcattttgagaagcgcttcctaaagaggatccgtgac
ttgggagagggccactttgggaaggttgagctctgcaggtatgaccccgaaggggacaat
acaggggagcaggtggctgtcaaatctctgaagcctgagagtggaggtaaccacatagct
gatctgaaaaaggaaatcgagatcttaaggaacctctatcatgagaacattgtgaagtac
aaaggaatctgcacggaagacggaggaaatggtattaagctcatcatggaatttctgcct
tcgggaagccttaaggagtatcttccaaagaataagaacaaaattaacctcaaacagcag
ctaaaatatgccgttcagatttgtaaggggatggactatttgggttctcggcaatatgtt
caccgtgacttggcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattgga
gacttcggtttaaccaaagcaattgaaaccgataaggagtattacaccgtcaaggatgac
cgggacagccctgtgttttggtatgctccagaatgtttaatgcaatctaaattttatatc
gcctctgacgtctggtcttttggagtcactctgcatgagctgctgacttactgtgattca
gattctagtcccatggctttgttcctgaaaatgataggcccaacccatggccagatgaca
gtcacaagacttgtgaatacattaaaagaaggaaaacgcctgccctgcccgcctaactgt
ccagatgaggtttatcaacttatgaggaaatgctgggaattccaaccatccaatcggaca
agctttcagaaccttattgaaggatttgaagcacttttaaaataa
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integrated database retrieval system
