Theropithecus gelada (gelada): 112620929
Help
Entry
112620929 CDS
T08041
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00230
Purine metabolism
tge00670
One carbon pool by folate
tge01100
Metabolic pathways
tge01523
Antifolate resistance
Module
tge_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112620929 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
112620929 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112620929 (GART)
Enzymes [BR:
tge01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
112620929 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
112620929 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
112620929 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
Dala_Dala_lig_C
ATP-grasp_4
ATP-grasp_3
Sacchrp_dh_NADP
RimK
ATP-grasp_5
GAE_BBS1
Motif
Other DBs
NCBI-GeneID:
112620929
NCBI-ProteinID:
XP_025235758
Ensembl:
ENSTGEG00000026945
UniProt:
A0A8D2GDN2
LinkDB
All DBs
Position
3:29262392..29300588
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNNAISISDHTALAQ
FCKEEKIEFVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWKAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
QVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFSEA
QALGLEVFHAGTALKNGKVVTHGGRVLAVTAIRENLVSALEEAKKGLAAIKFEGAIYRKD
IGFRAIAFLQQPRGLTYKESGVDIAAGNTLVKKIQPLAEATSRSGCKVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSFLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPKVFSWLQQEG
QLSEEEMARTFNCGVGAALVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
LIESMQINRSVLKNGSLKNHFSFEKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKNRVEFDNAIDLVLEEFSIDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSERVKLAEHKTFPAALQLVASGTVQLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttataattggcagtggaggaagggaacatacgctggcctggaaa
cttgcacagtctcatcatgtcaaacaagtgttggttgccccaggaaacgcaggcactgcc
tgctctgaaaagatttcaaataacgccatctcaatcagtgaccacactgcccttgctcaa
ttctgcaaagaggagaaaattgaattcgtagttgttggaccagaagcacctctggctgct
gggattgttgggaacctgacgtctgcaggagtgcgatgctttggcccaacagcagaagcg
gctcagttagagtccagcaaaaggtttgccaaagagtttatggacagacatggaatccca
actgcgcaatggaaggctttcaccaaacctgaagaggcctgcagcttcattatgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcggctggaaaaggggtgattgtt
gcaaagagcaaagaagaggcctgcaaagctgtacaagagatcatgcaggagaaagccttt
ggggcagccggagaaacaattgtcattgaagaacttcttgacggagaagaagtgtcttgt
ctgtgcttcactgatggcaagactgtggcccccatgccaccggcgcaggaccataagcga
ttactggagggagatggcggccctaacacagggggaatgggagcctattgtccggcccct
caggtttctaatgatctattactaaaaattaaagatactgttcttcagaggacagtggat
ggcatgcagcaagagggtactccatatacaggtattctctatgctggaataatgctgacc
aaggatggcccaaaagttctagagtttaactgccgttttggtgatccagagtgccaagta
atcctcccacttcttaaaagtgatctttatgaagtgattcagtccaccttagatggactg
ctctgcacatctctgcctgtttggctagaaaaccacacagccctaactgttgtcatggca
agtaaaggttatcctggagactacaccaagggtgtagaaataacagggttttccgaggct
caagctctaggactggaggtgttccacgcaggcactgcccttaaaaatggcaaagtagta
actcatgggggtagagttcttgcagtcacagccatccgggaaaatctcgtatcagctctc
gaggaagccaagaaaggactagcagctataaagtttgagggagcaatttataggaaagac
attggctttcgtgccatagctttcctccagcagcccaggggtttgacttacaaggaatct
ggagtagacattgcagctggaaatactctggtcaagaaaattcagcctttagcagaagcc
acttccagatcaggctgtaaagttgatcttggaggttttgctggtctttttgatttaaaa
gcagctggtttcaaagatccccttctggcctctggaacagatggcgttggaactaaacta
aagattgcccagctgtgcaacaaacatgataccattggtcaagatttggtagcaatgtgt
gttaatgatattctggcacaaggagcagagcccctcttcttccttgattacttttcctgt
ggaaaacttgacctcagtgtaactgaagctgttgttgctggaattgccaaagcttgtgga
aaagctggatgtgctcttcttggaggtgaaacagcagaaatgcctgacatgtatccccct
ggagagtatgacctagctgggtttgccgttggtgccatggagcgagatcagaaactccct
cacctggaaagaatcaccgagggtgatgttgttgttggaatagcttcatctggtcttcat
agcaatggatttagccttgtgaggaagatcgtggcaaaatctttcctccagtactcctct
ccagcacctgatggttgtggtgaccagactttaggggacttacttctcacgccaaccaga
atctacagccattcactgttacctgtcctacgttcaggacatgtcaaagcgtttgcccat
attactggtggaggattactagagaacatccccagagtcctccctgagaaacttggggta
gatttagatgcccagacctggaggatccccaaagtcttctcatggttacagcaggaagga
caactctctgaggaggagatggccagaacatttaactgtggggttggcgctgcccttgtg
gtatcaaaggagcagacagagcagattctgagggatatccagcagcataaggaagaagcc
tgggtgattggcagtgtggttgcacgagctgaaggttctccacgtgtgaaagtcaagaat
ctgattgaaagcatgcaaataaatcggtcagtgttgaagaatggctccctgaaaaatcat
ttctcttttgaaaaaaaaaaggccagagtggctgtcttaatatctggaacaggatcgaac
ctgcaagcacttatagacagtactcgggaaccaaatagctctgcacaaattgatgttgtt
atctccaacaaagccgcagtagctgggttagataaagcggaaagagctggtattcccact
agagtaattaatcataaactgtataaaaatcgtgtagaatttgacaatgcaattgaccta
gtccttgaagagttctccatagacatagtctgtcttgcaggattcatgagaattctttct
ggcccctttgtccgaaagtggaatggaaaaatgctcaatatccacccatccttgctccct
tcttttaagggttcgaatgcccatgagcaagccctggaaaccggagtcacagttactggg
tgtactgtacactttgtagctgaagatgtagatgctggacaaattattttgcaagaagct
gttcctgtgaagaggggtgatactgttgcaactctttctgaaagagtaaaattagcagaa
cataaaacatttcctgcagccctccagttggtggccagtggaactgtacagcttggagaa
aatggcaagatctgttgggttaaagaggaatga
DBGET
integrated database retrieval system
