KEGG   Theropithecus gelada (gelada): 112622487
Entry
112622487         CDS       T08041                                 
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
  KO
K18438  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
Organism
tge  Theropithecus gelada (gelada)
Pathway
tge00230  Purine metabolism
tge01100  Metabolic pathways
tge04024  cAMP signaling pathway
tge05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:tge00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    112622487 (PDE10A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    112622487 (PDE10A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    112622487 (PDE10A)
Enzymes [BR:tge01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     112622487 (PDE10A)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     112622487 (PDE10A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 SpoVT_C HD DUF7334
Other DBs
NCBI-GeneID: 112622487
NCBI-ProteinID: XP_025238030
Ensembl: ENSTGEG00000028872
UniProt: A0A8D2GKY5
LinkDB
Position
4:126037281..126375038
AA seq 791 aa
MEGSTPWSSEAEPQEERSQMLQRAGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLK
RKNNKSEDESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATK
ADGFALYFLGECNNSLCIFTPPGIKEGKPRLIPAGPITQGTTISAYVAKSRKTLLVEDIL
GDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLA
WASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCA
LFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYA
DPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFC
ALALHCANMYHRIRHSECIYRVTMEKLSYHSICTAEEWQGLMRFTLPVRLCKEIELFHFD
IGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMY
AILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNTYLQKFDHPLAALYSTSTMEQHHFSQ
TVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNN
QSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDK
KDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETATWISSP
SVAQKAAASED
NT seq 2376 nt   +upstreamnt  +downstreamnt
atggaagggagcacgccctggagttcagaagccgagcctcaagaggaaagaagccagatg
ctccagagagcaggtttgacagatgaaaaagtgaaggcatatctttctcttcacccccag
gtattagatgaatttgtatctgaaagtgttagtgcagagacagtagagaaatggctgaag
aggaagaacaacaaatcagaagatgaatcggctcctaaggaagtcagcaggtaccaagat
acgaatatgcagggagttgtatatgaactaaacagctatatagaacaacggttggacaca
ggaggagacaaccagctactcctctatgaactgagcagcatcatcaaaatagccacaaaa
gctgatggatttgcattgtatttccttggagagtgcaataatagcctgtgcatattcaca
ccacccgggataaaggaaggaaaaccccgcctcatccctgctgggcccatcactcagggc
accaccatctctgcttacgtggccaagtccaggaaaacattgctagtcgaagacatcctt
ggagatgagcgatttccaagaggtactggactggaatcagggactcgtatccagtctgtt
ctttgcttaccaattgtcactgcaattggtgacttgattggtattcttgagctgtatcgg
cactggggcaaagaagccttctgtcttagtcaccaggaggttgcaacagcaaatcttgcc
tgggcttcagtagcaatacatcaggtgcaggtatgcagaggccttgccaaacagactgaa
ttgaatgactttctactcgacgtatcaaaaacatattttgataacatagttgcaatagat
tctctacttgaacacataatgatatatgcaaaaaacctggtgaatgccgaccgttgtgca
cttttccaggtagaccataagaacaaggagttatattcagacctttttgatattggagag
gaaaaggaaggaaaacccgtcttcaagaagaccaaagagataagattttcaattgagaaa
ggaattgctggccaggtagcaagaacaggggaagtcctgaacattccagatgcctatgca
gacccacgctttaacagagaagtagacttgtacacaggctacaccacgcggaacatcctg
tgcatgcccatcgtcagccgaggcagcgtgataggtgtggtgcagatggtcaataaaatc
agtggcagtgccttctctaaaaccgatgaaaacaacttcaaaatgtttgccgtcttttgt
gctttagccttacactgtgctaatatgtatcatagaattcgccactcagagtgcatttac
cgggtaacaatggaaaagctgtcctaccatagcatttgtactgcagaagagtggcaaggc
ctcatgcgatttacccttcctgtgcgtctctgcaaagaaattgaattattccactttgac
attggtccttttgaaaacatgtggcctggaatttttgtctacatggttcatcggtcctgt
gggacatcctgctttgagctcgaaaagttgtgtcgttttattatgtctgtgaagaagaac
tatcggcgggttccttatcacaactggaagcatgcggtcactgtagcacactgcatgtac
gccatacttcagaacaaccacacgcttttcacagaccttgagcgcaaaggactgctgatt
gcgtgtctgtgtcatgacctagaccacagaggcttcagtaacacctacctgcagaagttc
gaccaccctctagcagctctctactccacttccaccatggagcagcaccacttctcccag
accgtgtccatcctccagctggaagggcacaatatcttctccactctgagctccagtgaa
tacgagcaggtgcttgagatcatccgcaaagccatcattgccacagaccttgctttatac
tttggaaacaggaaacagttggaagagatgtaccagaccggatcgctaaaccttaataat
caatcacatagagaccgtgtaattggtttgatgatgactgcctgtgacctttgttctgtg
acaaaactgtggcccgttacaaaattgacggcaaatgatatatatgcagaattctgggct
gagggtgatgaaatgaagaaattgggaatacagcctattcctatgatggacagagacaag
aaggatgaagtcccccaaggccagcttgggttctacaatgccgtagccattccctgctat
acaacccttacccagatcctccctcccacggagcctctccttaaagcatgcagggataat
ctcaatcagtgggagaaggtgattcgaggggaggagactgcaacctggatttcatccccg
tccgtggctcagaaggcagctgcatctgaagattga

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