Theropithecus gelada (gelada): 112623839 Help Entry 112623839         CDS       T08041                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism tge  Theropithecus gelada (gelada) Pathway tge04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:tge00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     112623839 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:tge03036]     112623839 (SYNE1) Chromosome and associated proteins [BR:tge03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     112623839 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 CH SYNE1 KASH Spectrin_SYNE1_2 SYNE3 Motif Other DBs NCBI-GeneID:  112623839 NCBI-ProteinID:  XP_025240303 Ensembl:  ENSTGEG00000026471 UniProt:  A0A8D2GDF9 LinkDB All DBs Position 4:113546278..114075094 Genome browser AA seq 8797 aa AA seqDB search MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPS IVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNA KKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLEKVKGRSNRENLE DAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNAGTDGQEDDEILP GFPSFANSIQNFKREDRLILKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEM KRKQIEHLVQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYR AEVALREEITIQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPD QLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLL QNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVE VRSVRSMLEEVISNWDRYGSTVASLQAWLEDAEKMLNQSEIAKKDFFRNLPHWIQQHTAM NDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTL SAFATEAHKKLCEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQE EGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITV LEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQ IADVHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELL RRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLL HLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQL IEELCVKLPVRDPVRDTPGTCHATLKELRAAIDSTYRKLMEDPDKWKDYTNRFSEFSSWI STNETQLKGIKGEAIDTANHGGVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENQA QKQGDELAKLSSSFKALVTLLSEVEKMVSNFGDCVQYKEIVKNSLEELISGSKEVQEQAE KILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQVQQGEGGLPDRGREELRKLEST LDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELE QTKEFSKRTENIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKDQVKKLEDTLEEDIKT MEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSI VGLEEEAQSFAQFVTTGESARIKAKLTQIRRYWEELREHAQCLEGTILGHLSQQQKFEEN LRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSLITTFSASARKVV NRDSCIQEAAALQHQYEDTLRKAKERQTALENLLAHWQRLEKELSSFLTWLERGEAIASS PEMDISADRVKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSIASKDDVKMVKLHLE QLDERWRDLPQIIDKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSEISIMDHQ VALTRHKDHAAEVESKKVELQSLQGHLARLGSLGRAEDLHLLQGKAEDCFQLFEEASQVV ERRQLALSHLAEFLQSHASLSGILHQLRQTVEATNSMNKNESDLIEKDLNDALQDAKALE SAAVSLDGILSKAQYHLKSGSSEQRTSCRATADQLCGEVERIQNLLGTKQSEADALAVLK KAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKD KAKQIAQKDVAFAPEVDREINRLAVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSK VLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGKYLLSELKKIH SSDFSLVKTDMESTVDKWLDVAEKLEENMDRLRVSLSIWDDVLSSRDEIEGWSNNSVPQM AKNISNLDNRLRAEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEAD LRQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWLAKVEESLMNCAQTDTCEGLK KVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELENLGCAMTGLIKKHEAVSQLCSKTQ ASLQESLEKHFSESMQEFQEWFLAAKASAKESSDRTGDSKVLEAKLHDLQNILDSVSDGQ SKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSF EDQHRKLNLWIHEMEERFNTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQR GQLLSEEGHGAGQEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWSWV KAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQ RVIQTQLETLKEVWADIMSSSIHAQSTLESVISQWNDYLERKNQLEQWMESVDQKVEHPL QPQPGLKEKFALLDRLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQEELKTQ FNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKL SKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQT QSCLENLVSQMALSEQEFSGQAAQLEQALQEFSALLKTWAQQLTLLEGKNTDEEIVECWH KGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQN KEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQHK LNVMLSKGELLSTLLTKEKAKGIQAKVSGAKEDWKNFHSNLHQKESALENLKIQMKDFEV SAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQL WEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAI HMLDSYCHPTSDKSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGECVLQNTSPEGIPTIQ QQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDDVRQFSGWMDSMEANLNESERQHA ELRDKISMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERYRAIQERA KEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQV HCAEGQALLNSVLHTREDVIPSGIPQAEDRALESLRQDWQVYQHKLSETRTQFNNVVNKL RLMEQKFQQVDEWLKTAEEKISPRTIRQSNRATKEIQLHQMKKWHEEVTAYRDEVEEVGA RAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDW YGSTHKNFKNVATKIDKVDTTMMGKKLRTLEVLLKDMEKGHSLLKSAREKGERAVKYLEE GEAERLRKEIHDHVEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILR VPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQLQ SDYQDLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLLETSSLETIT QQLAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAI CSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLSTVQPDLEPSPQPPLSRAEAVKQVKHFR ALQEQARTYLDLLCSMCDLSNASVKTTAKDIQLTEQMIEQRLVQAQNLTQGWEEIKHLKA ELWIYLQDADQQLQNMKRRHSELELSIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLT KKEESPEHKEINHLNDQWLDLCHQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEKFTTEW DNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLSLDDKELVKEQTSH LEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMDWAEEQQPNIAEALKQSPPPDMA QNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDL VGQRRKYLNKALSEKSQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQVKTCKSAQ ASLKTYQNEVTGLWAQGRELMKGVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKN LVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQHILEQSPEYENLLL MLQRTGQTILPSLNEVDHSYLSEKLNTLPQQFNVIVALAKDKFYKVQEAILARKEYASLI ELTTQSLSELEAQFSRMSKVPTDLAVEEAVALQDGCRAILDEVVGLGEAVDELNQKKEGF RSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEE QSKVNEETLPAEEKLKMYHSLGGSLQDSAILLKRVTIHLEDLAPHLDPLAYEKARHQIQS WQEELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVSLDLNLQDI QEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSELDGDIQEA LRTRQATLTEMYSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESAEENLKNHMEFFS TEDQFHSNLEELRGLVATLDPLIKPTGKEDLEQKMASLELRSQRMSQDSCAQADLLQRCT AQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIV ALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWTGFNNKV KKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQALSMLQ DGAAPTPGGEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQ ETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKDKYLGLYTILPAELSLQL AEVALDLKIRDQIQDKIKEVEQSKAMSQELSRQIQKIAKDLTTILTKLKAKTDNLVQAKT DQKVLGEELDGCNSKLMELDAAVQEFSEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLS KLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIH SDLEVMTEKLQYLTSVYCTEKMSQQVAELGRETEELQQMIKIRLQNLQDAAKDMKKFEAE LKKLQTALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPE DVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQLIEGAHRE IEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTE VEGLAEGTEDLDGELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACR SPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQELYEPGLEPSATAKLGDL QRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQM AEHQALMDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMK ASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLSTKATLDTALGTPKEPMDME AQLVDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQ RALHDKQLNMQGTAQEKEESDVDLTATQSPGVQEWLAQARTTWTHQRQSSLQQQKELEQE LAEQKSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEKSSAEDQMRMKWE SLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPIQDKSAVTSLLDGLNQ AFEEVSSQSGGTKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQE ILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMK ERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKELDAGI IELKRRGDKLQIEQPSMQELSKLQDMYDELMMTIGSRRSGLNQNLTLKSQYERALQDLAD LLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVQKET QFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVENSIPSVGLVEE NEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGERWLSNT NKVSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLN AFLEFSKEVDAKSSLKSSVLSTGNQLLRLKKVDTATLRSELSHIDSQWTDLLTNIPAVQE KLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSVGYKAINEYLQKYKGFKIDI NCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGL LESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEK IEQNGLALIQNKKEDVSGIVVSTLQELGQTWANLDHMVGQLKILLKSVLDQWSNHKVAFD KINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKE CHPPVTETLTNTLKEVNMRWNNLLEEIAEQLHSSKALLQLWQRYKDYSKQCASSVQQQED RTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFVLRELGEQLKQQVDASAAS AIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQGQDP SHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLI SSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELF QAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDS QIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGS YILTVEAGKQLLLSADSGAEAALQAELTEIQEKWKSASVRLEEQKKKLAFLLKDWEKCEK GIADSLEKLRTFKKKLSQCLPDHHEELHAEQMRCKELENAVGSWTDDLTQLTLLKDTLSA YISADDISILNERIELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQME SKVSQNGDILIEEMIEKLKKDYQEEIAVAQENKIQLQQMGERLAKASHESKASEIEYKLG KVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSE EIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRW RNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKTSERTAAFPSSSGVIYTVAKEELK KFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSIL RRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNH NKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEH DLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNPSLSLAQPLRSERSGRDTPASVDS IPLEWDHDYDLSRDLESAVSRALPSEDEESQDDKDFYLRGAVGLSGDHSALESQIRQLGK ALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSGSIDSVKRLEHKLKEEEES LPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTE EELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDL QDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPID SNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGN RLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPR GKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPDRSSRAFLFRVLRAALPLQLLLLLLIG LACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL NT seq 26394 nt NT seq  +upstreamnt  +downstreamnt atggcaacctccagaggggcctcccggtgtcctcgggatatcgccaatgtgatgcagagg ctgcaagatgagcaagagatagtacaaaaacgaactttcacaaaatggatcaactctcat ctggccaagcggaaacctccaatggtggtggatgatctttttgaagacatgaaagatggt gttaaactgcttgcccttctggaggtcctgtctgggcagaagctgccttgtgaacaagga cgccggatgaagcgaatccatgctgtggctaacattggcacggcactcaagttcctcgaa ggaagaaagattaaattagtcaacattaactccaccgatatagctgacggccgaccctca atagttcttggattgatgtggaccattattctatatttccagatcgaagagttgaccagc aacctgccccagctccagtctttgtccagcagcgcatcctccgtggacagcatagttagc tctgagactcccagcccaccaagtaaacggaaggtgaccaccaagatccaaggaaatgct aagaaggctttattaaagtgggttcagtacacggctggcaagcagactggaatagaagta aaagattttgggaagagttggagaagcggggttgcctttcattcagttattcatgccatt cgacccgaactggtggacttggagaaagtgaaaggcagatccaaccgagaaaatctggag gatgctttcactatcgccgaaacggaactggggatcccaagactgctagatcctgaagat gttgatgtggataaaccagatgagaagtctattatgacctatgtagcccagtttctgaaa cattatcctgacatccacaatgcaggcactgatgggcaagaggatgatgaaatacttcca ggtttcccatcttttgcaaattctatacaaaattttaagagagaagacaggctaattttg aaggaaatgaaagtttggatagaacaatttgagagagatttgacaagagcacagatggtg gaatcaaatttacaggataaatatcagtcatttaagcacttcagagttcaatacgaaatg aagaggaaacagattgaacatttagtacaaccattacatagagatggtaaattgtcactt gaccaagcattggtaaaacaatcttgggatagagtgacttccaggctctttgactggcat atacagcttgataaatctcttcctgcacctctgggcaccataggtgcctggctgtacaga gcggaggtggccctgagagaggaaataaccattcagcaggtccacgaggaaacagcaaac acgatacaacggaaacttgagcaacataaggatctgcttcaaaacacagatgcccacaaa agagcattccatgaaatctaccggaccaggtctgttaacgggattccagtgccacctgat caattagaggacatggccgagaggtttcattttgtttcctccacatcggagctacactta atgaaaatggaatttttagaattaaagtaccgtctgctttcactgctggttcttgcagag tcaaagctgaagtcttggatcattaagtacgggaggagagagtcagtggagcagcttcta caaaactacgtgtcttttatagaaaatagcaagttctttgaacaatatgaagtgacatac cagatcttgaaacagacagctgagatgtatgtcaaagcagatggttcagtggaagaagcg gagaatgtgatgaaattcatgaatgaaaccactgctcagtggaggaatctctcagtagaa gttaggagtgtgaggagcatgctggaggaagtgatctctaactgggatcgctatggcagt acagtggctagtctgcaagcctggctagaggatgctgaaaaaatgctcaatcaatcagaa attgccaaaaaggatttttttcgaaatttacctcattggattcagcagcatactgccatg aatgatgctggcaattttctaattgaaacctgtgatgagatggtttcccgtgacctgaag cagcaattactgttgctaaatgggcggtggagggagttgtttatggaagtcaagcaatat gctcaagctgatgagatggacagaatgaagaaggaatacacagactgtgttgttaccctg tctgcttttgcaacggaagcccataagaaactttgtgaacccttagaagtctcttttatg aatgtcaagttattaattcaagacttggaggatattgagcagagggtgcctgtgatggat gcccaatacaagataattacaaagacagcacacctcattaccaaagaaagcccccaagaa gaaggaaaagaaatgtttgcaacaatgtcaaagctcaaagagcagctaaccaaggtcaaa gaatgttactccccactcctttatgagtctcagcagctgttgattccgttggaggaatta gaaaagcagatgacgtccttttatgactcacttgggaaaatcaatgaaattatcacagtt cttgagcgtgaggcacaatcgagtgctctttttaaacaaaaacatcaggaactgttagct tgtcaagaaaactgtaagaaaaccttgacacttattgagaaaggcagtcaaagtgttcaa aagtttgtgaccttgagcaacgtgttaaagcattttgatcagacgaggctacaaagacag attgcagatgttcatgttgcttttcagagtatggtaaagaaaactggagattggaagaag catgtggaaaccaacagtcgcttgatgaagaagtttgaggagtctcgagcagagttggag aaggtgctgcggattgctcaggagggcttggaggaaaagggggatccggaggagctcctg cggagacacactgagtttttcagtcagctggatcagagggtgctcaatgcgttcctgaaa gcttgtgatgaactcacggacatccttccagagcaggagcagcaggggcttcaggaagct gttcgaaagctccacaaacaatggaaggatcttcaaggagaagccccttatcatttgctt catctgaagattgacgtggagaagaataggttcttagcctctgtagaagaatgcagaact gagctggatcgagagaccaagctgatgccccaggaaggcagtgaaaagataattaaagag cacagggttttcttcagtgacaaaggtcctcatcatctctgtgagaaaaggttacagctc atcgaggaactctgtgtgaaactcccagtccgggatccagtaagggacacacctggaacc tgtcacgcgactctcaaagagctccgagctgccattgacagcacttacaggaagctcatg gaagacccagacaagtggaaggactacactaacagattctctgagttctcatcttggata tctacaaatgagacacaattaaaggggatcaagggtgaggccatcgatactgccaaccac ggaggggttaaacgtgccgttgaagagatcagaaatggtgttaccaaaaggggcgagacc ctcagctggctaaaatccaggctaaaagttttgacagaagtttcttctgagaaccaagcc caaaagcagggagatgaactggcaaaattatccagctctttcaaggctctggtgacgctg ctgtcagaggttgaaaagatggtaagcaattttggggactgtgtacagtacaaagaaata gtcaaaaattctcttgaagaattaatttctggctctaaagaagtccaggaacaagctgag aagatcttggatactgaaaatctgtttgaagcacagcagttacttcttcatcaccagcaa aagacaaagcggatctcagcaaagaagagagatgtgcagcagcagatcgcgcaggtgcag cagggagaaggagggttgcctgaccgaggccgtgaggagctgcggaagctggagagcacc ctggacggcctggagcgaagccgggagaggcaggagcgccgcatccaggtcacattaaga aaatgggagagatttgaaacaaacaaagaaacagtagtaagatacctttttcaaacaggt tccagtcatgaacgcttcttaagttttagcagtttggaaagtttatcttcagaattggaa caaacaaaggagttctctaaacggacagaaaatattgcagtccaggctgagaaccttgta aaggaagcttcagagataccacttgggccccaaaataagcagctgcttcaacagcaggcc aagtcaatcaaagaccaagtcaaaaaattagaagacacgcttgaagaagatattaaaacc atggaaatggtgaaaaccaagtgggatcattttggcagtaattttgagactctgtccgtc tggataactgagaaagaaaaagagctcaatgccttggaaacttcgtcatctgccatggac atgcaaatcagccaaattaaggtcacaattcaggaaatagaaagtaagcttagcagcatt 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ggacgtctcagtctcaaggagcagctctctcatcggcagcatctgttgtctgagatggag tcactgaagccgaaggtgcaagcagtgcagctctgccagagtgccctccggatccccgag gatgtggtcgccagcttacctctctgtcatgctgctctgcggctacaggaagaggccagt cggctgcagcacactgccatccagcagtgcaacatcatgcaggaggctgtggtgcagtat gaacaatatgagcaagaaatgaaacatctccagcaactgatagaaggagcccacagagag attgaggataaacctgttgccaccagtaacatacaggagctgcaggctcagatttctcgg catgaggagctggcgcagaaaattaagggctaccaggagcagatcgcttctttgaattcc aagtgcaagatgctgacgatgaaagccaagcacgccaccatgctgctgacggtgaccgag gtcgaggggctggcggaagggacggaggacctggacggggagctcctccccacgccttcg gcccacccctctgtggtcatgatgactgcaggtcgctgtcacactttgctgtcaccggtc actgaggagtctggggaggagggaaccaacagtgagatttcctctccgcctgcctgtcgc tccccttcacctgtggctaatacagatgcttctgttaaccaggacattgcatattaccaa gccttgtctgctgagaggttgcagacagatgccgcaaagattcaccccagcacatcagcg tcccaggagttgtatgaaccaggattggagccatccgctactgccaaactgggtgatctg cagcgttcttgggaaaccttaaagaatgtgatcagtgagaagcagcgcacactctatgaa gctttggaacgccagcagaagtaccaggactccctccagtccatctctacgaagatggag gccattgagctgaaactcagtgagagcccagagcccggcaggagtccagaaagccagatg gctgaacatcaggcattgatggatgagattctcatgctccaggatgaaatcaatgagctc cagtcctctctcgcagaggagctggtatccgagtcttgtgaggccgaccccgcggagcag ctggccttgcagtccacgctcactgtcttagccgagcgaatgtccaccatcaggatgaaa gcctcagggaaacggcagcttttggaggagaagttgaatgatcagctggaggaacaaagg caggaacaggccctgcagaggtatcgctgtgaagccgatgagctggacagctggctcttg agtaccaaggccactctggatactgcgctgggtacacccaaggagcccatggacatggag gcccagcttgtggactgccagaacatgctggtggaaatagagcagaaggtggtggcttta tcagagctgtcagtccacaatgagaacctgctgctggagggcaaagctcacaccaaggac gaggccgagcagctggctggaaagctgagaaggctcaaggggagcctgctggagctgcag agagccctgcacgataagcagctcaacatgcagggaacagcacaggagaaggaggagagc gatgttgacctaacagccacgcagagccccggcgtccaggaatggctggcccaagctcgc accacatggacccaccagcggcagagcagtctccagcaacaaaaagagttagaacaggaa ttagctgagcagaagagtctccttcgctcagtagccagtcgtggagaggagattctaatt caacattcggcagcagagacctctggtgacgctggcgaaaaacctgatgtgttatcccag gagttggggatggaaggggagaaatcatccgctgaagaccagatgagaatgaaatgggaa agcttacatcaagaatttagtaccaagcagaaactactacagaatgttctggaacaggaa caagagcaagtgctttatagcaggccaaatcgactcttgtctggtgtgccactgtacaaa ggggacgtgccgatccaagataaatctgcagttacgtctttgctggatggactgaaccag gccttcgaggaggtttcatcccagagtggagggacaaagaggcagagtatacacttggag cagaagttgtatgatggggtctcagccacctctacttggttggatgatgttgaagaacgt ttatttgttgccacagcacttttaccagaagaaacagaaacttgtctcttcaaccaagag attcttgccaaagacattaaggaaatgtctgaagaaatggataagaacaaaaacttgttt tcgcaagcttttccagagaatggtgataatcgagatgttattgaagatactttgggttgt cttttgggcaggttatccttgctagactcagtagtgaatcaacgatgtcatcagatgaaa gaaagacttcagcaaatactaaatttccagaatgatctgaaagtgctgtttacatcactg gctgacaacaaatacatcattctgcagaaactggcaaatgtatttgaacaacccgtagca gaacaaatagaggcaatacaacaggctgaagatggacttaaagaattggatgcaggaatc attgaattaaagagacgtggtgacaagttacagattgagcagccgtccatgcaagaactc tccaaactccaggacatgtatgatgagctcatgatgaccattggctctcggaggagtggc ctgaaccagaaccttacactcaagagtcagtatgagagggccctacaagatctggctgac ctgctagaaactggtcaggagaagatggcaggagaccagaaaatcatcgtgtcttccaaa gaggaaatccagcaactacttgacaaacataaggaatactttcaaggcctggaatctcat atgatcttgactgaaacactcttcagaaagataatcagctttgcagtccagaaggaaacc cagttccatacagagctgatggctcaggcttctgctgtactgaaacgggctcacaagagg ggtgtggagctggagtacattctagagacatggtcgcatctggatgaggaccagcaggag cttagcagacagctggaggtggtggaaaacagcatcccaagcgtgggtctggtggaggag aacgaggacaggcttattgaccgcataacactctaccagcatttaaaatctagccttaat gaataccagcccaaattatatcaagtattagatgatggcaaacgacttctgatatccatc agctgctcagatctagaaagtcaactaaatcaacttggagagcgctggctaagtaacacc aacaaagtgtctaaggaacttcacagactggaaacaatattgaaacactggaccagatac caaagtgaatctgcagatctaattcactggttacagtctgcaaaagacaggctagaattt tggactcagcaatctgtgacagtcccacaagagctggaaatggtccgggatcatctaaat gctttcctggagttttctaaagaagtggatgccaaatcttccctgaaatcatctgttctg agtactggaaatcagctccttcgactgaaaaaggtggacacagccacgctgcgctctgag ctgtcgcacattgatagccagtggactgacctgctaaccaatatcccagccgtccaggag aagctccaccagctccagatggataaactgccttcccgccatgccatttctgaagtcatg agttggatttctctaatggaaaatgttattcagaaggatgaagataatattaaaaattcc gtaggttacaaggcaattaatgaataccttcagaaatataagggttttaagatagacatt aactgtaaacagctgacggtggattttgtgaaccagtccgtgctacaaatcagcagtcag gatgtggaaagtaaacgtagtgataagactgattttgctgagcaacttggagcaatgaat aaaagttggcaaattctgcaaggtctagtaactgagaagatccagctgttggaagggtta ttggaatcttggtcagaatatgaaaataatgtacaatgtctgaaaacatggtttgaaact caggaaaagagactaaaacaacagcatcgaattggagatcaggcttctgttcaaaatgcg ctgaaagactgtcaggatctggaagatttgattaaagcaaaagaaaaagaagtagagaaa attgagcagaatggacttgctttgattcagaacaagaaagaagacgtctctggcattgtc gtgagcacactgcaagagctcggccaaacctgggcgaatttagatcacatggttggacaa ttaaagatactgttgaaatcagtgcttgaccaatggagtaatcacaaagtggcctttgac aagataaacagttacctcatggaggccagatactctctttcccgattccgtctgctgact ggctccttagaagctgtgcaagttcaggtggacaatcttcagaatctccaagatgatcta gaaaaacaggaaaggagcttacagaaatttggctctatcaccaaccaattattaaaagag tgccacccgcctgtgacagaaactcttaccaatacactgaaagaagtcaacatgagatgg aataacttgctggaagagattgctgagcagctacactccagcaaggccctacttcagctt tggcaaagatacaaggactactcgaaacagtgtgcttcgtcggttcagcagcaggaggat cgaaccaatgagctgttgaaggcagccacaaacaaggacatcgccgatgatgaggttgct acatggattcaagattgcaacgacctcctcaaaggactgggtacagttaaagactccctc tttgttctccgtgagctgggagagcaactgaagcaacaagtggatgcttcggcagcatca gctattcaatcggatcaactctctttgagtcaacacttgtgtgccctagagcaggctctc tgcaaacagcagacttcgttacaggctggagttcttgattatgaaacctttgccaagagt ttagaagctctggaggcctggatagtggaagctgaagaaatactacaagggcaggaccct agccattcatctgacctctccacaatccaggaaaggatggaagaacttaagggacagatg ttaaaattcagcagcatggctccagatttagaccgtctaaatgagcttggatatagatta cccttgaatgataaggaaatcaaaaggatgcagaatctgaaccgccattggtctctgatc tcctctcagactacagaaagattcagcaagttgcagtcatttttgctacaacatcagact ttcttggaaaaatgtgaaacatggatggagttcctagttcagacagaacaaaagttagca gtagagatttcaggaaattatcagcatcttttggaacagcagagagcacatgagttgttt caagccgagatgttcagtcgtcagcagattttgcactcaatcattattgatgggcaacgt cttctagaacaaggtcaagttgatgacagggatgaattcaacctgaaattgacactcctc agtaatcagtggcagggagtgattcgcagggcccagcagaggcgggggatcattgacagc cagattcgccagtggcaacgctatagggagatggcagaaaagcttcgtaaatggttggtt gaagtgtcctacctccccatgagtggtctcggaagtgttcctataccactgcaacaagca aggaccctctttgatgaagtgcagttcaaagaaaaggtgttcctgcggcaacaaggcagc tacatcctgactgtggaggctggcaagcaactccttctgtctgcggatagtggcgctgag gccgccttgcaggccgaactcactgaaatccaagagaaatggaaatcagccagcgtgcgg ctggaagaacagaagaaaaaactagccttcttgttgaaagactgggaaaaatgtgagaaa ggaatagcagattccctggagaaactacgaactttcaaaaagaagctttcccagtgtcta ccggatcaccacgaagagctccatgcagaacaaatgcgttgcaaggaattagaaaatgca gttgggagctggacagatgacttgacccagttgacgctgctgaaggacaccctctctgcc tacatcagtgctgatgatatctccattcttaatgaacgcatagagcttctgcaaaggcag tgggaagagctatgccaccagctctccttaaggcggcagcaaataggtgaaagattgaac gaatgggcagtcttcagtgaaaagaacaaggaactctgtgagtggttgactcaaatggaa agcaaggtttctcagaatggagacattctcattgaagaaatgatagagaagctcaagaag gattatcaagaggaaattgctgttgctcaagagaacaaaatacagctccaacaaatggga gaacgacttgctaaagccagccacgaaagcaaagcatctgagattgaatacaaactggga aaggttaatgaccggtggcagcatctcctggacctcattgcagccagggtgaagaagctg aaggagaccctggtggccgtgcagcagctcgataagaacatgagcagcctgaggacctgg ctcgctcacattgagtcagagctggccaagccaatagtctacgattcctgtaactcggaa gaaatacagagaaagcttaatgagcagcaggagcttcagagagacatagagaagcacagt acaggtgttgcatctgtcctcaacctgtgtgaagtcctgctgcacgactgtgatgcctgt gccactgatgccgagtgtgactctatccagcaggctacaagaaacctggaccggcggtgg agaaacatttgtgctatgtccatggaaaggagactcaaaatcgaagagacgtggcgattg tggcagaaatttctggatgactattcacgttttgaagattggctgaagacttcagaaagg acagctgcatttcccagctcttctggggtgatctatacagttgccaaggaagaactaaag aaatttgaggctttccagcgacaggtccacgagtgcctgacgcagctggaactgatcaac aagcagtaccgccgcctggccagagagaaccgcactgattcagcctgtagcctcaaacag atggttcacgaaggcaaccagagatgggacaacctgcaaaagcgcgtcacctccatcttg cgcagactcaagcattttattggccagcgtgaggagtttgagactgcgcgggacagcatt ctggtctggctcacagagatggatctgcagctcactaatattgaacatttttctgagtgt gatgttcaagctaaaataaagcaactcaaggccttccagcaggaaatttccctgaaccac aataagattgagcagataattgcccaaggagaacagctgatagaaaagagtgagcccttg gatgcggcgatcatcgaggaggaactagacgagctccgacggtactgccaggaggtcttc gggcgtgtggaaagataccataagaaactgatccgcctgcctctcccagatgatgagcat gacctctcggacagagagctggagctggaagactctgcggctctgtcggacctgcactgg catgaccgctctgcagacagcctcctttctccacagccttcctccaacccctccctgtcg ctcgctcagcccctccggagcgaacggtcgggacgagacaccccggctagtgtggactcc atccccctggagtgggatcatgactatgacctcagtcgggacctggagtctgcagtgtcc agagctctgccctctgaggatgaagagagtcaggatgacaaagatttctacctccgggga gctgttggcttatcaggggaccacagcgccctagagtcacagatccgacaactgggcaaa gccctggatgatagccgctttcagatacagcaaaccgaaaatatcattcgcagcaaaact cccacggggccagagctagacaccagctacaaaggctacatgaaactgctgggcgaatgc agtggcagtatagactccgtgaagagactggagcacaaactgaaggaggaagaggagagc cttcctggctttgttaacctgcatagtaccgaaacccaaacggctggtgtgattgaccga tgggagcttctccaggcccaggcgttgagcaaggagctgaggatgaagcagaacctccag aagtggcagcagtttaactcggacttgaacagcatctgggcctggctgggggacacggag gaggagctggaacagctccagcgtctggaactcagcactgacatccagacaatcgagctc cagatcaaaaagctcaaggagctccagaaagccgtggaccaccgcaaagccatcatcctc tccatcaatctctgcagccctgagttcacccaggctgacagcaaggagagtcgggacctg caggatcgcttgtcacagatgaatgggcgctgggaccgagtgtgttctctgctggaggag tggcggggcctactgcaagatgccctgatgcagtgccagggtttccatgaaatgagccat ggtttgcttcttatgctggagaacattgacagaaggaaaaatgaaattgtccctattgat tctaaccttgatgcagagatacttcaggaccatcacaaacagcttatgcaaataaagcat gagctgttggaatcccaactcagagtagcctctttgcaagacatgtcttgccaactactg gtgaatgctgaaggaacagactgtttagaagccaaagaaaaagtccatgttattggaaat cggctgaaacttctcttgaaggaggtcagtcgtcatatcaaggaactggagaagttatta gacgtgtcaagtagtcagcaggatttgtcttcctggtcttctgctgatgaactggacacc tcagggtctgtgagtcccacatcaggaaggagcaccccaaacagacagaaaacgccacga ggcaaatgtagtctctcacagcctggaccctctgtcagcagtccacatagcaggtccaca aaaggtggctccgattcctccctttctgagcctgggccagatcggtccagccgcgccttc ctgttcagagtcctccgagcagctcttccccttcagcttctcctgctgctcctcatcggg ctcgcctgccttgtaccaatgtcagaggaagactacagctgtgccctctccaacaacttt gcccggtcattccaccccatgctcagatacacgaatggccctcctccactctga

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