KEGG   Theropithecus gelada (gelada): 112624557
Entry
112624557         CDS       T08041                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
tge  Theropithecus gelada (gelada)
Pathway
tge04010  MAPK signaling pathway
tge04020  Calcium signaling pathway
tge04022  cGMP-PKG signaling pathway
tge04114  Oocyte meiosis
tge04218  Cellular senescence
tge04310  Wnt signaling pathway
tge04360  Axon guidance
tge04370  VEGF signaling pathway
tge04380  Osteoclast differentiation
tge04625  C-type lectin receptor signaling pathway
tge04650  Natural killer cell mediated cytotoxicity
tge04658  Th1 and Th2 cell differentiation
tge04659  Th17 cell differentiation
tge04660  T cell receptor signaling pathway
tge04662  B cell receptor signaling pathway
tge04720  Long-term potentiation
tge04724  Glutamatergic synapse
tge04728  Dopaminergic synapse
tge04921  Oxytocin signaling pathway
tge04922  Glucagon signaling pathway
tge04924  Renin secretion
tge05010  Alzheimer disease
tge05014  Amyotrophic lateral sclerosis
tge05020  Prion disease
tge05022  Pathways of neurodegeneration - multiple diseases
tge05031  Amphetamine addiction
tge05152  Tuberculosis
tge05163  Human cytomegalovirus infection
tge05166  Human T-cell leukemia virus 1 infection
tge05167  Kaposi sarcoma-associated herpesvirus infection
tge05170  Human immunodeficiency virus 1 infection
tge05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tge05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112624557 (PPP3CA)
   04310 Wnt signaling pathway
    112624557 (PPP3CA)
   04370 VEGF signaling pathway
    112624557 (PPP3CA)
   04020 Calcium signaling pathway
    112624557 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    112624557 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    112624557 (PPP3CA)
   04218 Cellular senescence
    112624557 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    112624557 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    112624557 (PPP3CA)
   04660 T cell receptor signaling pathway
    112624557 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    112624557 (PPP3CA)
   04659 Th17 cell differentiation
    112624557 (PPP3CA)
   04662 B cell receptor signaling pathway
    112624557 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    112624557 (PPP3CA)
   04921 Oxytocin signaling pathway
    112624557 (PPP3CA)
   04924 Renin secretion
    112624557 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    112624557 (PPP3CA)
   04728 Dopaminergic synapse
    112624557 (PPP3CA)
   04720 Long-term potentiation
    112624557 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    112624557 (PPP3CA)
   04380 Osteoclast differentiation
    112624557 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112624557 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112624557 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    112624557 (PPP3CA)
   05163 Human cytomegalovirus infection
    112624557 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112624557 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    112624557 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112624557 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    112624557 (PPP3CA)
   05020 Prion disease
    112624557 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    112624557 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    112624557 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112624557 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:tge01009]
    112624557 (PPP3CA)
Enzymes [BR:tge01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     112624557 (PPP3CA)
Protein phosphatases and associated proteins [BR:tge01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     112624557 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 112624557
NCBI-ProteinID: XP_025241058
Ensembl: ENSTGEG00000026414
UniProt: A0A8D2G894
LinkDB
Position
5:complement(98538610..98876856)
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcctaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gttccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataatgatggaaaa
cctcgtgtggatatcttaaaggcacatcttatgaaggagggaagactggaagagagtgtt
gcattgagaataataacagagggtgcatcaattcttcgacaggaaaaaaacttgctggat
attgatgcgccagtcacagtttgtggggacattcatggacaattctttgacttgatgaag
ctctttgaagtcgggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgtatggat
gcctttgactgccttcccttggctgccctgatgaaccaacagttcctgtgtgtacatggt
ggcttgtctccagagattaacaccttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcatatggacctatgtgtgatatcctgtggtcagaccccctggaagattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcgtacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatacttcgagcc
catgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacagggttccct
tctctaattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgttatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgtttttacttggtccctgccttttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctctgatgatgaactagggtcagaa
gaagatggatttgatggtgcaacagctgcagcccggaaggaggtgataaggaacaagatc
cgagcaataggcaaaatggccagagtgttctcagtgctcagagaagagagtgagagtgtg
ctgacgctgaaaggcttgaccccgactggcatgctccccagcggagtactttctggaggg
aagcaaaccctacaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaagccaagggcttagaccgaattaat
gagaggatgccgcctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctctcacctcagagactaacggcacggacagcaatggcagtaatagcagcaatatt
cagtga

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