KEGG   Theropithecus gelada (gelada): 112624632
Entry
112624632         CDS       T08041                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
tge  Theropithecus gelada (gelada)
Pathway
tge01522  Endocrine resistance
tge04010  MAPK signaling pathway
tge04012  ErbB signaling pathway
tge04014  Ras signaling pathway
tge04024  cAMP signaling pathway
tge04068  FoxO signaling pathway
tge04071  Sphingolipid signaling pathway
tge04137  Mitophagy - animal
tge04140  Autophagy - animal
tge04141  Protein processing in endoplasmic reticulum
tge04210  Apoptosis
tge04215  Apoptosis - multiple species
tge04217  Necroptosis
tge04310  Wnt signaling pathway
tge04380  Osteoclast differentiation
tge04510  Focal adhesion
tge04530  Tight junction
tge04620  Toll-like receptor signaling pathway
tge04621  NOD-like receptor signaling pathway
tge04622  RIG-I-like receptor signaling pathway
tge04625  C-type lectin receptor signaling pathway
tge04657  IL-17 signaling pathway
tge04658  Th1 and Th2 cell differentiation
tge04659  Th17 cell differentiation
tge04660  T cell receptor signaling pathway
tge04664  Fc epsilon RI signaling pathway
tge04668  TNF signaling pathway
tge04722  Neurotrophin signaling pathway
tge04723  Retrograde endocannabinoid signaling
tge04728  Dopaminergic synapse
tge04750  Inflammatory mediator regulation of TRP channels
tge04910  Insulin signaling pathway
tge04912  GnRH signaling pathway
tge04914  Progesterone-mediated oocyte maturation
tge04917  Prolactin signaling pathway
tge04920  Adipocytokine signaling pathway
tge04926  Relaxin signaling pathway
tge04930  Type II diabetes mellitus
tge04931  Insulin resistance
tge04932  Non-alcoholic fatty liver disease
tge04933  AGE-RAGE signaling pathway in diabetic complications
tge04935  Growth hormone synthesis, secretion and action
tge04936  Alcoholic liver disease
tge05010  Alzheimer disease
tge05012  Parkinson disease
tge05016  Huntington disease
tge05017  Spinocerebellar ataxia
tge05020  Prion disease
tge05022  Pathways of neurodegeneration - multiple diseases
tge05132  Salmonella infection
tge05133  Pertussis
tge05135  Yersinia infection
tge05142  Chagas disease
tge05145  Toxoplasmosis
tge05152  Tuberculosis
tge05161  Hepatitis B
tge05162  Measles
tge05166  Human T-cell leukemia virus 1 infection
tge05167  Kaposi sarcoma-associated herpesvirus infection
tge05169  Epstein-Barr virus infection
tge05170  Human immunodeficiency virus 1 infection
tge05171  Coronavirus disease - COVID-19
tge05200  Pathways in cancer
tge05208  Chemical carcinogenesis - reactive oxygen species
tge05210  Colorectal cancer
tge05212  Pancreatic cancer
tge05231  Choline metabolism in cancer
tge05415  Diabetic cardiomyopathy
tge05417  Lipid and atherosclerosis
tge05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tge00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    112624632 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112624632 (MAPK10)
   04012 ErbB signaling pathway
    112624632 (MAPK10)
   04014 Ras signaling pathway
    112624632 (MAPK10)
   04310 Wnt signaling pathway
    112624632 (MAPK10)
   04668 TNF signaling pathway
    112624632 (MAPK10)
   04068 FoxO signaling pathway
    112624632 (MAPK10)
   04071 Sphingolipid signaling pathway
    112624632 (MAPK10)
   04024 cAMP signaling pathway
    112624632 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112624632 (MAPK10)
   04137 Mitophagy - animal
    112624632 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    112624632 (MAPK10)
   04215 Apoptosis - multiple species
    112624632 (MAPK10)
   04217 Necroptosis
    112624632 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112624632 (MAPK10)
   04530 Tight junction
    112624632 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    112624632 (MAPK10)
   04621 NOD-like receptor signaling pathway
    112624632 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    112624632 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    112624632 (MAPK10)
   04660 T cell receptor signaling pathway
    112624632 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    112624632 (MAPK10)
   04659 Th17 cell differentiation
    112624632 (MAPK10)
   04657 IL-17 signaling pathway
    112624632 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    112624632 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112624632 (MAPK10)
   04920 Adipocytokine signaling pathway
    112624632 (MAPK10)
   04912 GnRH signaling pathway
    112624632 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    112624632 (MAPK10)
   04917 Prolactin signaling pathway
    112624632 (MAPK10)
   04926 Relaxin signaling pathway
    112624632 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    112624632 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    112624632 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    112624632 (MAPK10)
   04722 Neurotrophin signaling pathway
    112624632 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112624632 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112624632 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112624632 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    112624632 (MAPK10)
   05231 Choline metabolism in cancer
    112624632 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112624632 (MAPK10)
   05212 Pancreatic cancer
    112624632 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112624632 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    112624632 (MAPK10)
   05161 Hepatitis B
    112624632 (MAPK10)
   05171 Coronavirus disease - COVID-19
    112624632 (MAPK10)
   05162 Measles
    112624632 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112624632 (MAPK10)
   05169 Epstein-Barr virus infection
    112624632 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112624632 (MAPK10)
   05135 Yersinia infection
    112624632 (MAPK10)
   05133 Pertussis
    112624632 (MAPK10)
   05152 Tuberculosis
    112624632 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    112624632 (MAPK10)
   05142 Chagas disease
    112624632 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112624632 (MAPK10)
   05012 Parkinson disease
    112624632 (MAPK10)
   05016 Huntington disease
    112624632 (MAPK10)
   05017 Spinocerebellar ataxia
    112624632 (MAPK10)
   05020 Prion disease
    112624632 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    112624632 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112624632 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    112624632 (MAPK10)
   05415 Diabetic cardiomyopathy
    112624632 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    112624632 (MAPK10)
   04936 Alcoholic liver disease
    112624632 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    112624632 (MAPK10)
   04931 Insulin resistance
    112624632 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    112624632 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    112624632 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tge01001]
    112624632 (MAPK10)
Enzymes [BR:tge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     112624632 (MAPK10)
Protein kinases [BR:tge01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   112624632 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 112624632
NCBI-ProteinID: XP_025241213
Ensembl: ENSTGEG00000008019
LinkDB
Position
5:55492606..55845755
AA seq 467 aa
MVFMSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDST
FTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKC
VNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGI
KHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILG
MGYKENVDMWSVGCIMGEMIKGAVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRNY
VENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHP
YINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPS
GAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1404 nt   +upstreamnt  +downstreamnt
atggtatttatgagcctccatttcttatactactgcagtgaaccaacattggatgtgaaa
attgccttttgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattac
aacatgagcaaaagcaaagttgacaaccaattctacagcgtggaagtgggagactcaacc
ttcacagttctcaagcgctaccagaatctaaagcctattggctctggggctcagggcata
gtttgtgccgcgtatgatgctgtccttgacagaaatgtggccattaagaagctcagcaga
ccctttcagaaccaaacccatgccaagagagcgtaccgggagctggtcctcatgaagtgt
gtgaaccataaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggag
gagttccaagatgtttacttagtaatggaactgatggatgccaacttatgtcaagtgatt
cagatggaattagaccacgagcgaatgtcttacctgctgtaccaaatgctgtgtggcatt
aagcacctccactctgctggaattattcacagggatttaaaaccaagtaacattgtagtc
aagtctgattgcacattgaaaatcctggactttggactggccaggacagcaggcacaagc
ttcatgatgactccatatgtggtgacacgttattacagagccccggaggtcatcctgggg
atgggctacaaggagaacgttgacatgtggtcagtagggtgcatcatgggagaaatgata
aaaggtgcagtgctgtttcctggcactgatcatattgaccagtggaataaggtaattgaa
caactaggaacaccatgtccagaattcatgaagaaattgcaacccacagtaagaaactat
gtggagaatcggcccaagtatgcgggactcaccttccccaagctcttcccagattccctc
ttcccagcggactccgagcacaataaactcaaagccagccaagccagggacttgttgtca
aagatgctagtgattgacccagcaaaaagaatatcagtggatgacgccttacagcatccc
tacatcaacgtctggtatgacccagccgaagtggaggcgcctccacctcagatatatgac
aagcagttggatgaaagagaacacacaatcgaagaatggaaagaacttatctacaaggaa
gtaatgaactcagaagagaagactaaaaatggcgtagtaaaaggacagccttctccttca
ggtgcagcagtgaacagcagtgagagtctccctccatcctcgtctgtcaatgacatctcc
tccatgtccaccgaccagaccctggcatctgacactgacagcagcctggaagcttcggca
ggacccctgggttgttgcaggtga

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