Theropithecus gelada (gelada): 112626238
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Entry
112626238 CDS
T08041
Symbol
PDE4B
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00230
Purine metabolism
tge01100
Metabolic pathways
tge04024
cAMP signaling pathway
tge04928
Parathyroid hormone synthesis, secretion and action
tge05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112626238 (PDE4B)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
112626238 (PDE4B)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
112626238 (PDE4B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
112626238 (PDE4B)
Enzymes [BR:
tge01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
112626238 (PDE4B)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
112626238
NCBI-ProteinID:
XP_025243921
Ensembl:
ENSTGEG00000012964
UniProt:
A0A8D2F811
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All DBs
Position
1:93634299..94220310
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AA seq
736 aa
AA seq
DB search
MKKSRSVMTVTADDNVKDYFECSLSKSYSSSSTTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSSGLVL
HTTFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKK
KQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSH
NRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHV
LLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS
SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI
SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSP
SPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
NT seq
2211 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaagcaggagtgtgatgacagtgacggccgatgataatgttaaagattatttt
gaatgtagcttgagtaaatcatacagttcttccagtaccacacttgggatcgacctctgg
agagggagaaggtgttgctcaggaaacttacagttaccaccgctgtctcaaagacagagt
gaaagggcaaggactcctgagggagatggtatttccaggccgaccacactacctttgaca
acgcttccaagcattgctattacaactgtaagccaggagtgctttgatgtggaaaatggc
ccttccccaggtcggagtccactggatccccaggccagctcttcctctgggctggtactt
cacaccacctttcctgggcacagccagcgcagagagtcatttctctacagatcagacagc
gactatgacttgtcaccaaaggcgatgtcgagaaactcttcgcttccaagcgagcaacat
ggcgatgacttgattgtaactccttttgcccaggtccttgccagcttgcgaagtgtgaga
aacaacttcactatactgacaaaccttcatggtacatctaacaagcggtctccagctgct
agtcagcctcctgtctccagagtcaacccgcaagaagaatcttatcaaaaattagcaatg
gaaacgctggaggaattagactggtgtttagaccagctagagaccatacagacctaccgc
tctgtcagtgagatggcttctaacaagttcaaaagaatgctgaaccgggagctgacacac
ctctcagagatgagccggtcagggaaccaggtgtctgaatacatttcaaatactttctta
gacaagcagaatgatgtggagatcccatctcccacccagaaagacagggagaaaaagaaa
aagcagcagctcatgacccagataagtggagtgaagaaattaatgcatagttcaagctta
aacaatacaagcatctcacgctttggagtcaacactgaaaatgaagatcacctggccaag
gaactggaagacctgaacaaatggggtcttaacatctttaatgtggctggatattcccac
aataggcccctaacatgcatcatgtatgctatattccaggaaagagacctcctgaagaca
ttcagaatctcatctgatacatttataacctacatgatgactttagaagaccattaccat
tccgacgtggcatatcacaacagcctgcacgctgctgatgtagctcagtcaacccacgtt
ctcctttctacaccagcattagacgctgtcttcacagatttggaaatcctggcagccatt
tttgcagctgccatccatgacgttgatcatcctggagtctccaatcagtttctcatcaac
acaaattcagaacttgctttgatgtataatgatgaatctgtgttggaaaatcatcacctt
gctgtgggtttcaaactgctgcaagaagaacactgtgacatcttcatgaatctcacgaag
aagcagcgtcagacactcaggaagatggttattgacatggtgttagcaactgatatgtct
aaacatatgagcctgctggcagacctgaagacaatggtagaaacgaagaaagttacaagt
tcaggcgttcttctcctagacaactatactgatcgcattcaggtccttcgcaacatggtg
cactgtgcagacctgagcaaccccaccaagtccttggaattgtatcggcaatggacagac
cgcatcatggaggaatttttccagcagggagacaaagagcgggagaggggaatggaaatt
agcccaatgtgtgataaacacacagcttctgtggaaaaatcccaggttggtttcatcgac
tacattgtccatccattgtgggagacctgggcagatttggtacagcctgatgctcaggac
attctcgataccttagaagataacaggaactggtatcagagcatgatacctcaaagtccc
tcaccaccactggacgagcagaacagggactgccagggtctgatggagaagtttcagttt
gaactgactctcgatgaggaagattctgaaggacctgagaaggagggagagggacacagc
tatttcagcagcacaaagacgctttgcgtgattgatccagaaaacagagattccctggga
gagactgacatagacattgcaacagaagacaagtccccagttgatacataa
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