Theropithecus gelada (gelada): 112628312
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Entry
112628312 CDS
T08041
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial isoform X1
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00020
Citrate cycle (TCA cycle)
tge00480
Glutathione metabolism
tge01100
Metabolic pathways
tge01200
Carbon metabolism
tge01210
2-Oxocarboxylic acid metabolism
tge01230
Biosynthesis of amino acids
tge04146
Peroxisome
tge05230
Central carbon metabolism in cancer
Module
tge_M00009
Citrate cycle (TCA cycle, Krebs cycle)
tge_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
112628312 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
112628312 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
112628312 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
112628312 (IDH2)
Enzymes [BR:
tge01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
112628312 (IDH2)
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
112628312
NCBI-ProteinID:
XP_025246835
Ensembl:
ENSTGEG00000006801
LinkDB
All DBs
Position
7b:5055973..5073315
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AA seq
475 aa
AA seq
DB search
MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQTRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE
ARVEVGGSGREALKIHLQTPQACPCPAEFKLKKMWKSPNGTIRNILGGTVFREPIICKNI
PRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGV
GMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTD
FEKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP
DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQT
LEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atggccggctacctgcgggtcgtgcgctcgctctgcagagcctcaggctcgcggccggcc
tgggcgccggcggccctgacagcccccacctcgcaagagcagacgaggcgccactatgct
gacaaaaggatcaaggtggcaaagcctgtggtggagatggatggtgatgagatgacccgt
attatctggcagttcatcaaggagaagctcatcctgccccacgtggacatccagctaaag
tattttgacctcgggctcccaaaccgtgaccagaccgatgaccaggtcaccattgactct
gcattggccacccagaagtacagtgtggctgtcaagtgtgccaccatcacccctgatgag
gcccgtgtggaagtcggagggagcgggcgggaagcactcaagatacatctgcaaactccc
caggcctgcccctgtcctgcagagttcaagctgaagaagatgtggaaaagtcccaatgga
actatccggaacatcctgggggggactgtcttccgggagcccatcatctgcaaaaacatc
ccacgcctcgtccctggctggaccaagcccatcaccattggcaggcacgcccatggcgac
cagtacaaggccacagactttgtggcagaccgggctggcacgttcaaaatggtcttcacc
ccgaaagatggcagcggtgtcaaggagtgggaagtgtacaacttccccgcaggcggtgtg
ggcatgggcatgtacaacaccgatgagtccatctcgggtttcgcgcacagctgcttccag
tatgccatccagaagaaatggccgctgtacatgagcaccaagaacaccatactgaaagcc
tacgatgggcgtttcaaggacatcttccaggagatctttgacaagcactataagaccgac
ttcgagaagaataagatctggtatgagcaccggctcattgatgacatggtggctcaggtc
ctcaagtcttcgggcggctttgtgtgggcctgcaagaactatgacggagatgtgcagtca
gacatcctggcccagggctttggctctcttggcctgatgacatctgtcctggtctgccct
gatgggaagacgattgaggctgaggctgctcatgggaccgtcacccgccactatcgggag
caccagaagggccggcccaccagcaccaaccccatcgccagcatctttgcctggacacgt
ggcctggagcaccgagggaaactggatgggaaccaggacctcatcaggtttgcccagacg
ctggagaaggtgtgcgtggagacggtggagagcggagccatgaccaaggacctggcgggc
tgcattcatggcctcagcaatgtgaagctgaacgagcacttcctgaacaccacggacttc
ctcgacaccatcaagagcaacctggacagagccctgggcaggcagtag
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