Theropithecus gelada (gelada): 112628505
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Entry
112628505 CDS
T08041
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge01521
EGFR tyrosine kinase inhibitor resistance
tge01522
Endocrine resistance
tge04010
MAPK signaling pathway
tge04014
Ras signaling pathway
tge04015
Rap1 signaling pathway
tge04066
HIF-1 signaling pathway
tge04068
FoxO signaling pathway
tge04081
Hormone signaling
tge04114
Oocyte meiosis
tge04140
Autophagy - animal
tge04144
Endocytosis
tge04150
mTOR signaling pathway
tge04151
PI3K-Akt signaling pathway
tge04152
AMPK signaling pathway
tge04211
Longevity regulating pathway
tge04213
Longevity regulating pathway - multiple species
tge04510
Focal adhesion
tge04520
Adherens junction
tge04550
Signaling pathways regulating pluripotency of stem cells
tge04730
Long-term depression
tge04913
Ovarian steroidogenesis
tge04914
Progesterone-mediated oocyte maturation
tge05200
Pathways in cancer
tge05202
Transcriptional misregulation in cancer
tge05205
Proteoglycans in cancer
tge05214
Glioma
tge05215
Prostate cancer
tge05218
Melanoma
tge05224
Breast cancer
tge05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112628505 (IGF1R)
04014 Ras signaling pathway
112628505 (IGF1R)
04015 Rap1 signaling pathway
112628505 (IGF1R)
04066 HIF-1 signaling pathway
112628505 (IGF1R)
04068 FoxO signaling pathway
112628505 (IGF1R)
04151 PI3K-Akt signaling pathway
112628505 (IGF1R)
04152 AMPK signaling pathway
112628505 (IGF1R)
04150 mTOR signaling pathway
112628505 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
112628505 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
112628505 (IGF1R)
04140 Autophagy - animal
112628505 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
112628505 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
112628505 (IGF1R)
04520 Adherens junction
112628505 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
112628505 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
112628505 (IGF1R)
04914 Progesterone-mediated oocyte maturation
112628505 (IGF1R)
09156 Nervous system
04730 Long-term depression
112628505 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
112628505 (IGF1R)
04213 Longevity regulating pathway - multiple species
112628505 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112628505 (IGF1R)
05202 Transcriptional misregulation in cancer
112628505 (IGF1R)
05205 Proteoglycans in cancer
112628505 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112628505 (IGF1R)
05214 Glioma
112628505 (IGF1R)
05218 Melanoma
112628505 (IGF1R)
05215 Prostate cancer
112628505 (IGF1R)
05224 Breast cancer
112628505 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112628505 (IGF1R)
01522 Endocrine resistance
112628505 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tge01001
]
112628505 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tge04090
]
112628505 (IGF1R)
Enzymes [BR:
tge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
112628505 (IGF1R)
Protein kinases [BR:
tge01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
112628505 (IGF1R)
CD molecules [BR:
tge04090
]
Proteins
112628505 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
112628505
NCBI-ProteinID:
XP_025247159
Ensembl:
ENSTGEG00000011082
UniProt:
A0A8D2EY03
LinkDB
All DBs
Position
7b:17277252..17595114
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSGSGEGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDLEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctctggagaagggtccccgacctcgctgtgggggctcctgtttctctcc
gccgcgctctcgctctggccgacgagcggagaaatctgtgggccgggcatcgacatccgc
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacttgctgttgttccgagtggctggcctagagagcctcggagacctgttc
cccaacctcacggtaatccgcggctggaaactcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttacaacctgaggaacattactcggggggcc
atcaggattgagaaaaatgctgacctctgttacctctccactgtggactggtccctgatc
ctggatgcagtgtccaataattacattgtggggaataagcccccaaaggaatgcggggat
ctgtgtccggggaccatggaggagaagccgatgtgcgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgcccgagtgcctgtggg
aagagggcatgcaccgagaacaatgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcctgacaacgacacggcctgtgtagcttgccgccactactactacgccggcgtctgc
gtgcctgcctgcccgcccaacacctacaggtttgagggctggcgctgtgtggaccgtgac
ttctgcgccaacatcctcagcgccgagagcagcgactccgagggttttgtgatccacgac
ggcgagtgcatgcaggagtgcccctcaggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacttctgctcagatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaacatccgacgggggaataatattgcttcagaactggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccgccattcccatgccttggtctccttgtcc
ttcctaaaaaaccttcgcctcatcttaggagaggagcagctagaagggaattactccttc
tacgtcctcgacaaccagaacttgcagcaactatgggactgggaccaccgcaacctgacc
atcaaagcagggaaaatgtactttgctttcaatcccaaattgtgtgtttcggaaatttac
cgcatggaggaggtgacggggactaaagggcgccaaagcaaaggggacataaacaccagg
aacaacggggagagagcctcctgtgaaagtgacgtcctgcatttcacctccaccaccacg
tggaagaatcgcatcatcataacctggcaccggtaccggccccctgactacagggatctc
atcagcttcaccgtttactacaaggaagcaccttttaagaatgtcacggagtatgatggg
caggatgcctgcggctccaacagctggaacatggtggacgtggacctcccgcccaacaag
gacgtggagcccggcatcttactgcatgggctgaagccctggactcagtacgccgtttac
gtcaaggctgtgaccctcaccatggtggagaacgaccatatccgtggggccaagagtgag
atcttgtacattcgcaccaatgcttcagttccttccattcccttggacgttctttcagca
tcgaactcctcttctcagttaatcgtgaagtggaaccctccctctctgcccaacggcaac
ctgagttactacattgtgcgctggcagcggcagcctcaggacggctacctttaccggcac
aattactgctccaaagacaaaatccccatcaggaagtatgccgacggcaccattgacatt
gaggaggtcacagagaacccgaagactgaggtgtgtggtggagagaaagggccttgctgc
gcctgccccaaaactgaagctgagaagcaggccgagaaggaggaggctgagtaccgcaaa
gtctttgagaatttcctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gatgtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacggcggca
gacacctacaacatcacagatctggaagagctagagacagagtaccctttctttgagagc
agagtggataataaggagagaactgtcatttctaaccttcggcctttcacattgtaccgc
attgatatccacagctgcaaccacgaagctgagaaactgggctgcagcgcctccaacttt
gtctttgcaaggactatgcctgcagaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatacggatcacaagttgaggatcagcgagaatgtgtg
tccagacaggaatacaggaagtatggaggggccaagctaaaccggctaaacccagggaac
tacacagcccggattcaggctacatctctctctgggaatgggtcgtggacagatcctgtg
ttcttctatgtccaggccaaaacaggatatgaaaacttcatccatctgatcatcgctctg
cccgtcgctgtcctgttgatcgtgggagggttggtgatcatgctgtacgtcttccataga
aagagaaataacagcaggctggggaatggagtgctgtacgcatctgtgaacccggagtac
ttcagcgctgcggatgtgtacgttcctgatgagtgggaggtggctcgggagaagatcacc
atgagccgggaacttgggcaggggtcgtttgggatggtctatgaaggagttgccaagggt
gtggtgaaagacgaacctgaaaccagagtggccattaaaacagtgaacgaggccgcgagc
atgcgtgaaaggatcgagtttctcaacgaggcttctgtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggtgtggtgtcccagggccagccaacgctggtcatcatggaa
ctgatgacgcggggtgatctcaaaagttatctccggtctctgaggccagaaatggagaat
aatccagtcctagcacctccaagcctaagcaagatgattcagatggctggagagattgca
gacggcatggcatacctcaacgccaacaagttcgtccacagagaccttgctgcccggaat
tgcatggtagccgaggatttcacagtcaaaattggagattttgggatgacgcgagatatc
tatgagacagactattaccggaaaggagggaaagggctgttgcccgtgcgctggatgtct
cccgagtccctcaaggatggagtcttcaccacttactcggacgtctggtccttcggggtt
gtcctctgggagatcgccacactggccgagcagccctaccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggcggccttctggacaagccagacaactgccccgacatg
ctgtttgaattgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaagacgagatggagcctggcttccgggaggtctccttctac
tacagtgaggagaacaagctgcccgagccggaggagctggacctggagccagagaacatg
gagagcgtccccctggacccctcggcctcctcgtcctccctgccactgcccgacagacac
tcaggacacaaggccgagaacggccccggccctggagtgctggtgctccgtgccagcttc
gatgagagacagccttacgcacacatgaacggtggccgcaagaacgagcgggccttgccg
ctgccccagtcttcgacctgctga
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integrated database retrieval system
