Theropithecus gelada (gelada): 112628758
Help
Entry
112628758 CDS
T08041
Symbol
SOS2
Name
(RefSeq) LOW QUALITY PROTEIN: son of sevenless homolog 2
KO
K03099
son of sevenless
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge01521
EGFR tyrosine kinase inhibitor resistance
tge01522
Endocrine resistance
tge04010
MAPK signaling pathway
tge04012
ErbB signaling pathway
tge04014
Ras signaling pathway
tge04062
Chemokine signaling pathway
tge04068
FoxO signaling pathway
tge04072
Phospholipase D signaling pathway
tge04150
mTOR signaling pathway
tge04151
PI3K-Akt signaling pathway
tge04510
Focal adhesion
tge04540
Gap junction
tge04630
JAK-STAT signaling pathway
tge04650
Natural killer cell mediated cytotoxicity
tge04660
T cell receptor signaling pathway
tge04662
B cell receptor signaling pathway
tge04664
Fc epsilon RI signaling pathway
tge04714
Thermogenesis
tge04722
Neurotrophin signaling pathway
tge04810
Regulation of actin cytoskeleton
tge04910
Insulin signaling pathway
tge04912
GnRH signaling pathway
tge04915
Estrogen signaling pathway
tge04917
Prolactin signaling pathway
tge04926
Relaxin signaling pathway
tge04935
Growth hormone synthesis, secretion and action
tge05034
Alcoholism
tge05160
Hepatitis C
tge05161
Hepatitis B
tge05163
Human cytomegalovirus infection
tge05165
Human papillomavirus infection
tge05200
Pathways in cancer
tge05205
Proteoglycans in cancer
tge05206
MicroRNAs in cancer
tge05207
Chemical carcinogenesis - receptor activation
tge05208
Chemical carcinogenesis - reactive oxygen species
tge05210
Colorectal cancer
tge05211
Renal cell carcinoma
tge05213
Endometrial cancer
tge05214
Glioma
tge05215
Prostate cancer
tge05220
Chronic myeloid leukemia
tge05221
Acute myeloid leukemia
tge05223
Non-small cell lung cancer
tge05224
Breast cancer
tge05225
Hepatocellular carcinoma
tge05226
Gastric cancer
tge05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112628758 (SOS2)
04012 ErbB signaling pathway
112628758 (SOS2)
04014 Ras signaling pathway
112628758 (SOS2)
04630 JAK-STAT signaling pathway
112628758 (SOS2)
04068 FoxO signaling pathway
112628758 (SOS2)
04072 Phospholipase D signaling pathway
112628758 (SOS2)
04151 PI3K-Akt signaling pathway
112628758 (SOS2)
04150 mTOR signaling pathway
112628758 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
112628758 (SOS2)
04540 Gap junction
112628758 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
112628758 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
112628758 (SOS2)
04660 T cell receptor signaling pathway
112628758 (SOS2)
04662 B cell receptor signaling pathway
112628758 (SOS2)
04664 Fc epsilon RI signaling pathway
112628758 (SOS2)
04062 Chemokine signaling pathway
112628758 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
112628758 (SOS2)
04912 GnRH signaling pathway
112628758 (SOS2)
04915 Estrogen signaling pathway
112628758 (SOS2)
04917 Prolactin signaling pathway
112628758 (SOS2)
04926 Relaxin signaling pathway
112628758 (SOS2)
04935 Growth hormone synthesis, secretion and action
112628758 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
112628758 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
112628758 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112628758 (SOS2)
05206 MicroRNAs in cancer
112628758 (SOS2)
05205 Proteoglycans in cancer
112628758 (SOS2)
05207 Chemical carcinogenesis - receptor activation
112628758 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
112628758 (SOS2)
05231 Choline metabolism in cancer
112628758 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
112628758 (SOS2)
05225 Hepatocellular carcinoma
112628758 (SOS2)
05226 Gastric cancer
112628758 (SOS2)
05214 Glioma
112628758 (SOS2)
05221 Acute myeloid leukemia
112628758 (SOS2)
05220 Chronic myeloid leukemia
112628758 (SOS2)
05211 Renal cell carcinoma
112628758 (SOS2)
05215 Prostate cancer
112628758 (SOS2)
05213 Endometrial cancer
112628758 (SOS2)
05224 Breast cancer
112628758 (SOS2)
05223 Non-small cell lung cancer
112628758 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
112628758 (SOS2)
05160 Hepatitis C
112628758 (SOS2)
05163 Human cytomegalovirus infection
112628758 (SOS2)
05165 Human papillomavirus infection
112628758 (SOS2)
09165 Substance dependence
05034 Alcoholism
112628758 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112628758 (SOS2)
01522 Endocrine resistance
112628758 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
IQ_SEC7_PH
Motif
Other DBs
NCBI-GeneID:
112628758
NCBI-ProteinID:
XP_025247755
Ensembl:
ENSTGEG00000007730
LinkDB
All DBs
Position
7b:complement(51458740..51575655)
Genome browser
AA seq
1227 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPEFNEHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCPFYSHQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHGQTRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSVVFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLA
IEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPAIEWHISKPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRVIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPVPTGAFMGLC
IVHLHHHQEILFLIPLHRFPFGLQNTL
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccttacgagttcttcagtgaggagaatagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggaacaagtgcatcccactctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccagccaaggactgttcaagatgtagaggagcgagttcagaagacctttcctcac
ccaattgataaatgggccattgctgatgcacaatctgctatagaaaaacgaaaaagaaga
aatcctcttttactgcctgtggacaaaatccatccttcgttgaaggaagtgttagggtac
aaagtggactaccatgtgtccctatatattgtggctgtactagaatatatctcagctgat
attttaaaattggctggtaattatgtttttaatatccggcattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcggataaggttttgatggacatgtttgatcaggatgat
ataggcttggtttctctctgtgaagatgaacctagttcttccggtgaattaaactactat
gatcttgtcagaactgaaattgcagaagaaagacagtatctacgggaattaaatatgatc
ataaaagtgtttcgagaagcctttctttctgatagaaagctgtttaaaccttctgatatt
gaaaagatttttagtaacatttcagatatacatgaattgactgtgaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttcaccagagtttaatgaacatttcaataaattgatggccagacctgcagttgctcta
cactttcagtctattgctgatggctttaaagaggcagttcgttatgtccttccacgtctt
atgctggtgccagtgtatcactgttggcactattttgagttactaaagcaattgaaagca
tgtagtgaagaacaagaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagcatggaccgaatttacaagcagcattcacctagacgccgacctggagat
cctgtttgccctttttatagtcaccaattaagaagcaaacacctggctatcaaaaaaatg
aatgaaattcagaaaaatatcgatggatgggaaggcaaagatattggacagtgttgtaat
gaattcattatggagggaccattgacaagaatcggtgccaaacatgaacggcatattttt
ctgtttgatggcttaatgatcagttgtaaacctaatcatggccagactcggcttccaggt
tacagtagtgcagaatacaggttaaaagaaaaatttgtcatgaggaaaatacaaatttgt
gataaagaagatacttgtgagtgcaagcatgcttttgaattagtatccaaagatgagaac
agcgtagtatttgctgctaagtctgctgaagaaaaaaacaactggatggcagcccttatt
tctcttcattatcgtagtactctagatcgaatgttagattcagtattactgaaagaagaa
aatgagcaaccactgagattaccaagtcctgaagtatatcgttttgtagtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggcatccccattattaaa
ggaggaactgtagtgaagttaattgaaaggttaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttaccacatatcgttcattttgtaaaccacaggaattgctgagc
ttactgattgaacggtttgaaatcccagagccagaacctactgacgcagacaaattggca
atagagaaaggcgagcagccaatcagtgcagaccttaaaagatttcgcaaggaatatgtc
caaccagtacaacttaggatcttaaatgtatttcggcattgggttgaacatcatttttat
gactttgaaagagatttggaattgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaatcgctaagatcatcaagaggaagaagcaa
gctcaggcaaacggaataagccataatattacctttgaaagtccacctccagcaattgaa
tggcatatcagcaaaccaggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggagtctgatctctacaggaaagttcaaccatct
gaacttgtaggaagtgtgtggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacaaatctcaccctctggtttgaaaaatgcattgtggaagca
gaaaattttgaagaacgggttgcagtactaagtagagttatagaaattctgcaagttttt
caagatttgaataatttcaatggcgtattggagatagtcagtgcagtaaattcagtgtca
gtatacagactagaccatacctttgaggcactgcaggaaagaaaaaggaaaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcagaatcagccttactgtttacgg
atagaaccagatatgaggagattctttgaaaaccttaaccccatgggaaatgcgtctgaa
aaagagtttacagattatttgttcaacaagtcactagaaattgaacctcgaaactgcaaa
cagccacctcgatttcctagaaaatcaactttctccttgaaatctcctggaataaggcct
aacacaggccgacatggctctacctcaggtactttacgaggtcacccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaactgagctggaatcaacagtg
tcagcaccaacttctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtatttttagatgtggatctcaacagctcctgtggcagcaatagcatctttgctcca
gtgcttttgccacattcaaagtctttctttagttcatgtggtagtttacataaactaagt
gaagagcccctgattcctcctcctcttcctcctcgaaaaaagtttgatcatgatgcttca
aattctaagggaaatatgaaatctgatgatgatcctcctgctattccaccgagacagcct
cctcctcccaaggtaaaacccagagttcctgttcctactggtgcatttatgggcctctgc
atagtccacctccaccaccaccaagagatcctcttcctgatacccctccaccggttcccc
ttcggcctccagaacactttataa
DBGET
integrated database retrieval system