Theropithecus gelada (gelada): 112629482 Help Entry 112629482         CDS       T08041                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism tge  Theropithecus gelada (gelada) Pathway tge00230   Purine metabolism tge01100   Metabolic pathways tge01522   Endocrine resistance tge04015   Rap1 signaling pathway tge04020   Calcium signaling pathway tge04022   cGMP-PKG signaling pathway tge04024   cAMP signaling pathway tge04062   Chemokine signaling pathway tge04072   Phospholipase D signaling pathway tge04081   Hormone signaling tge04082   Neuroactive ligand signaling tge04114   Oocyte meiosis tge04211   Longevity regulating pathway tge04213   Longevity regulating pathway - multiple species tge04261   Adrenergic signaling in cardiomyocytes tge04270   Vascular smooth muscle contraction tge04371   Apelin signaling pathway tge04540   Gap junction tge04611   Platelet activation tge04713   Circadian entrainment tge04714   Thermogenesis tge04723   Retrograde endocannabinoid signaling tge04724   Glutamatergic synapse tge04725   Cholinergic synapse tge04727   GABAergic synapse tge04742   Taste transduction tge04750   Inflammatory mediator regulation of TRP channels tge04911   Insulin secretion tge04912   GnRH signaling pathway tge04913   Ovarian steroidogenesis tge04914   Progesterone-mediated oocyte maturation tge04915   Estrogen signaling pathway tge04916   Melanogenesis tge04918   Thyroid hormone synthesis tge04921   Oxytocin signaling pathway tge04923   Regulation of lipolysis in adipocytes tge04925   Aldosterone synthesis and secretion tge04926   Relaxin signaling pathway tge04927   Cortisol synthesis and secretion tge04928   Parathyroid hormone synthesis, secretion and action tge04934   Cushing syndrome tge04935   Growth hormone synthesis, secretion and action tge04970   Salivary secretion tge04971   Gastric acid secretion tge04972   Pancreatic secretion tge04976   Bile secretion tge05032   Morphine addiction tge05163   Human cytomegalovirus infection tge05166   Human T-cell leukemia virus 1 infection tge05200   Pathways in cancer tge05207   Chemical carcinogenesis - receptor activation tge05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:tge00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     112629482 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     112629482 (ADCY4)    04371 Apelin signaling pathway     112629482 (ADCY4)    04020 Calcium signaling pathway     112629482 (ADCY4)    04072 Phospholipase D signaling pathway     112629482 (ADCY4)    04024 cAMP signaling pathway     112629482 (ADCY4)    04022 cGMP-PKG signaling pathway     112629482 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     112629482 (ADCY4)    04081 Hormone signaling     112629482 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     112629482 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     112629482 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112629482 (ADCY4)    04062 Chemokine signaling pathway     112629482 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     112629482 (ADCY4)    04923 Regulation of lipolysis in adipocytes     112629482 (ADCY4)    04912 GnRH signaling pathway     112629482 (ADCY4)    04913 Ovarian steroidogenesis     112629482 (ADCY4)    04915 Estrogen signaling pathway     112629482 (ADCY4)    04914 Progesterone-mediated oocyte maturation     112629482 (ADCY4)    04921 Oxytocin signaling pathway     112629482 (ADCY4)    04926 Relaxin signaling pathway     112629482 (ADCY4)    04935 Growth hormone synthesis, secretion and action     112629482 (ADCY4)    04918 Thyroid hormone synthesis     112629482 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     112629482 (ADCY4)    04916 Melanogenesis     112629482 (ADCY4)    04925 Aldosterone synthesis and secretion     112629482 (ADCY4)    04927 Cortisol synthesis and secretion     112629482 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     112629482 (ADCY4)    04270 Vascular smooth muscle contraction     112629482 (ADCY4)   09154 Digestive system    04970 Salivary secretion     112629482 (ADCY4)    04971 Gastric acid secretion     112629482 (ADCY4)    04972 Pancreatic secretion     112629482 (ADCY4)    04976 Bile secretion     112629482 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     112629482 (ADCY4)    04727 GABAergic synapse     112629482 (ADCY4)    04725 Cholinergic synapse     112629482 (ADCY4)    04723 Retrograde endocannabinoid signaling     112629482 (ADCY4)   09157 Sensory system    04742 Taste transduction     112629482 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     112629482 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     112629482 (ADCY4)    04213 Longevity regulating pathway - multiple species     112629482 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     112629482 (ADCY4)    04714 Thermogenesis     112629482 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112629482 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     112629482 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112629482 (ADCY4)    05163 Human cytomegalovirus infection     112629482 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     112629482 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     112629482 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     112629482 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     112629482 (ADCY4) Enzymes [BR:tge01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      112629482 (ADCY4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 DUF3180 Motif Other DBs NCBI-GeneID:  112629482 NCBI-ProteinID:  XP_025248890 Ensembl:  ENSTGEG00000022619 UniProt:  A0A8D2K6K3 LinkDB All DBs Position 7b:complement(25665036..25680865) Genome browser AA seq 1077 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLGIVLCALAALLVVAWASGRELTSDPS FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWVALLALGHAFLFTGGVVSAWDQV SYFLFVIFTVYAMLPLGMRDAAVAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL FLCGNVAGVYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVEDAGMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR YLESWGAAKPFAHLSHVDSPVSTSTPLQEKTLASFSPQWSLDRSRTLRGLDDELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSAIPAFKYYEACTFLVFLSNFI IQMLVTNRPPALAIMYSITFLLFLLLLFVCFSEDLMRCVLKGPKMLHWLPALSGLVATRP GLRIALGTATILLVFAMAITSLFFFPASSDCPFQAPNVSSMISNLSWELPGSLPLISVPY SMHCCTLGFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSDCLIVRLYLGPLDS RPGVLKEPKFMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETAWALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRSGPSSVTLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagcccccggccaccccccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccgctgctgctgctgctgctggggatcgtgctctgtgcg ctcgcggcgctgctcgtggttgcctgggccagcggcagggagctgacctcagacccgagc ttcctgaccactgtgctgtgcgcgctgggcggcttctcgctgctgctgggcctcgcttcc cgtgagcagcgactgcagcgctggacgcgtcctctgtctggcttggtatgggtcgcgctg ctagcgctaggccacgccttcctgttcaccgggggcgtggtgagcgcctgggaccaggtg tcctattttctcttcgtcatcttcacggtgtatgccatgctgcccttgggcatgcgggac gccgccgtcgcgggcctcgcctcctcactctcgcatctactggtcctggggctgtatctt ggaccacagccggactcacggcctgcactgctgccgcagttggcagcaaatgcggtgctg ttcctgtgcgggaacgtggcaggagtgtaccacaaggcgctgatggagcgcgccctgcgg gccacgttccgggaggcactcagctccttgcactcgcgccggcggctggacaccgaaaag aagcaccaggaacaccttctcttgtccatccttcctgcctacctggcccgagagatgaaa gcagagatcatggcacggctgcaggcaggacaggggtcacggccagagagcaccaacaat ttccacagcctctatgtcaagaggcaccagggagtcagtgtgctgtatgctgacattgtg ggcttcacgcggctggccagcgagtgttcccctaaggagctggtgctcatgctcaatgag ctctttggcaagttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg ggggactgttactactgtgtctccggactgccactctcactgccagaccatgccatcaac tgcgtgcgcatggggctggacatgtgccgggccatcaggaaactgcgggcagccactggc gtggacatcaacatgcgtgtgggcgtgcactcaggcagtgtactctgtggagtcatcggg ctgcagaagtggcagtatgacgtttggtcccatgatgtcacactggctaaccacatggag gcaggcggtgtaccagggcgagtgcacatcacaggggctaccctggccctgctggcaggg gcttatgctgtggaggacgcaggcatggagcatcgggatccctaccttcgggagctaggg gagcccacctatctggtcatcgatccacgggcagaggaggaggatgagaagggcactgca ggaggcttgctctcctcgcttgagggccccaagatgcgtccatcactgctgatgacccgt tacctggagtcctggggtgcagccaagccttttgcccacctgagccacgtagacagccct gtgtccacctccacccctctccaggagaagaccctggcttccttcagcccccagtggagc ctagatcggagccgtaccctccgtggactagatgatgaactggacaccggggatgccaag ttcttccaggtcattgagcagctcaactcacagaaacagtggaagcagtcgaaggacttc aacccactgacactgtacttcagagagaaggagatggagaaagagtaccgactctctgca atccccgccttcaaatactatgaagcctgcaccttcctggtttttctctccaacttcatc atccagatgctagtgacaaacaggcccccagctctggccatcatgtatagcatcaccttc ctcctcttcctcctcctcctttttgtctgcttctcagaggacctgatgaggtgtgtcctg aaaggccccaagatgctgcactggctgcctgcactgtctggcctggtggccacacgacca ggactgagaatagccttgggcaccgccaccatcctccttgtctttgccatggccattacc agcctgttcttcttcccagcatcatcagactgccctttccaagctcccaatgtgtcctcc atgatttccaacctctcctgggagctccctgggtctctgcctctcatcagtgtcccatac tccatgcactgctgcacgctgggcttcctctcctgctccctctttctgcacatgagcttc gaactgaagctgctgctgctcctgctgtggctggcagcatcctgctccctcttcctgcac tcccacgcctggctgtccgactgcctcatcgtccgcctctatctgggccccttggactcc aggcccggagtgctgaaggagcccaaattcatgggtgctatctccttcttcatcttcttc ttcaccctccttgtcctggctcgccagaatgagtactactgccgcctggacttcctgtgg aagaagaagctgaggcaggagcgggaggagacagagacgatggagaacctgactcggctg ctcttggagaacgtgctccctgcacacgtggccccccagttcattggccagaaccggcgc aacgaggatctctaccaccagtcctacgaatgcgtttgtgtcctcttcgcttcagtccca gacttcaaggagttctactctgaatccaacatcaatcatgagggcctagagtgtctgagg ctgctcaatgaaataattgctgattttgatgagctgctctccaagcccaagttcagtggg gtggagaagatcaagaccattggcagcacctacatggcagccacaggattaaatgccacc tctggacaggatgcacaacaggatgctgaacggagctgcagccaccttggcactatggtg gaatttgccgttgccctggggtctaagctggatgtcatcaacaagcattcattcaacaac ttccgcctgcgtgtggggttgaaccatggaccagtagtagctggagttattggggcccag aagccacaatatgacatttggggcaacacagtgaacgtggccagccgcatggagagtaca ggggtccttggcaaaatccaagtgactgaggagacagcctgggccctacagtccctgggc tacacctgctacagccggggggtcatcaaggtgaaaggtaaagggcagctctgcacctac ttcctgaacacagacttgacacgaagtggaccttcttcagttaccctaggctga

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