Theropithecus gelada (gelada): 112632129
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Entry
112632129 CDS
T08041
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00760
Nicotinate and nicotinamide metabolism
tge01100
Metabolic pathways
tge04068
FoxO signaling pathway
tge04148
Efferocytosis
tge04152
AMPK signaling pathway
tge04211
Longevity regulating pathway
tge04213
Longevity regulating pathway - multiple species
tge04218
Cellular senescence
tge04310
Wnt signaling pathway
tge04922
Glucagon signaling pathway
tge04936
Alcoholic liver disease
tge05031
Amphetamine addiction
tge05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
112632129 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
112632129 (SIRT1)
04068 FoxO signaling pathway
112632129 (SIRT1)
04152 AMPK signaling pathway
112632129 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
112632129 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
112632129 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
112632129 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
112632129 (SIRT1)
04213 Longevity regulating pathway - multiple species
112632129 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
112632129 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
112632129 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
112632129 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
tge03036
]
112632129 (SIRT1)
03029 Mitochondrial biogenesis [BR:
tge03029
]
112632129 (SIRT1)
Enzymes [BR:
tge01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
112632129 (SIRT1)
Chromosome and associated proteins [BR:
tge03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
112632129 (SIRT1)
Mitochondrial biogenesis [BR:
tge03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
112632129 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
DUF7108_C
Motif
Other DBs
NCBI-GeneID:
112632129
NCBI-ProteinID:
XP_025253653
Ensembl:
ENSTGEG00000029240
UniProt:
A0A8D2GKB5
LinkDB
All DBs
Position
9:complement(66213390..66248984)
Genome browser
AA seq
743 aa
AA seq
DB search
MADEAALALQPGGSPSAAGAEREAGSPPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREV
PAAGGCPVAAAALWREAEAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADSFYDED
DDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRPRIGP
YTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIE
DAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRK
DPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHG
SFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHR
AMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDV
IINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSDLPPTPLHISEDSSSPERT
SPPDSSVIVTLLDQAAKSNDDLDVSESKGRMEEKPQEVQTSRNVESIAEHMGNPDLKNVG
SSTGEKNERTSVAGTVRKCWPSRVAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDD
VLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDIPETAGGAGFGTDGDDQ
EAINEAISMKQEVTDMNYPSNKS
NT seq
2232 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggctgccctcgcccttcagcccggcggctccccctcggcggcgggggcc
gagagggaggccgggtcgccccccgccggggagccgctccgcaagaggccgcggagagat
ggtcctggcctcgagcggagcccgggcgagcccggtggggcagccccagagcgtgaggtg
ccggcggccgggggctgcccggttgcggcggcggcgctgtggcgggaggcagaggcggcg
gcggcgggcggggagcaagaggcccaagcgactgcggcggctggggaaggagacaatggg
ccgggcctgcagggcccatctcgggagccaccgctggccgacagcttctacgacgaagac
gacgacgacgagggcgaggaggaggaagaggcggcggcggcggcgattgggtaccgagat
aaccttctgttcggtgatgaaattatcactaatggttttcattcttgtgaaagtgatgag
gaggatagagcctcacatgcaagctctagtgactggactccaaggccacggataggtcca
tatacttttgttcagcaacatcttatgattggcacagatcctcgaacaattcttaaagat
ttattgccggaaacaattcctccacctgagttggatgatatgacactgtggcagattgtt
attaatatcctttcagaaccaccaaaaaggaaaaaacgaaaagatattaatacaattgaa
gatgctgtgaaattactgcaagagtgcaaaaaaattatagttctaactggagctggggtg
tctgtttcatgtggaatacctgacttcaggtcaagggatggtatttatgctcgccttgct
gtagacttcccagatcttccagatcctcaagcgatgtttgatattgaatatttcagaaaa
gatccaagaccattcttcaagtttgcaaaggaaatatatcctggacaattccaaccatct
ctctgtcacaaattcatagccttgtcagataaggaaggaaaactacttcgcaactatacc
cagaacatagacacgctggaacaggttgcaggaatccagaggataattcagtgtcatggt
tcctttgcaacagcatcttgcctgatttgtaaatacaaagttgactgtgaagctgtacga
ggagatatttttaatcaggtagttcctcgatgtcctaggtgcccagctgatgaaccgctt
gctatcatgaaaccagagattgtgttttttggtgaaaatttaccagaacagtttcataga
gccatgaagtatgacaaagatgaagttgacctcctcattgttattgggtcttccctcaaa
gtaagaccggtagcactaattccaagttccataccccatgaagtgcctcagatattaatt
aatagagaacctttgcctcatctgcattttgatgtagagcttcttggagactgtgatgtc
ataattaatgaattgtgtcataggttaggtggtgaatatgccaaactttgctgtaaccct
gtaaagctttcagaaattactgaaaaacccccacgaacacaaaaagaattggcttatttg
tcagacttgccacccacacctcttcatatttcagaagactcaagttcaccagaaagaact
tcaccaccagattcttcagtgattgtcacacttttagaccaagcagctaagagtaatgat
gatttagatgtgtctgaatcaaaaggtcgtatggaagaaaaaccacaggaagtacagact
tctaggaatgttgaaagtattgctgaacacatgggaaatccggatttgaagaatgttggt
tccagtactggggagaaaaatgaaagaacctcagtggctggaacagtgagaaaatgctgg
cctagtagagtggcaaaggagcagattagtaagcggcttgatggtaatcagtatctgttt
ttgccaccaaatcgttacattttccatggcgctgaggtatattcagactctgaagatgac
gtcttatcctctagttcttgtggcagtaacagtgatagtgggacatgccagagtccaagt
ttagaagaacccatggaggatgaaagtgaaattgaagaattctacaatggcttagaagat
gagcctgatattccagagacagctggaggagctggatttgggactgatggagatgatcaa
gaggcaattaatgaagctatatctatgaaacaggaagtaacagacatgaactatccatca
aacaaatcatag
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