Theropithecus gelada (gelada): 112634545 Help Entry 112634545         CDS       T08041                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism tge  Theropithecus gelada (gelada) Pathway tge00220   Arginine biosynthesis tge00330   Arginine and proline metabolism tge01100   Metabolic pathways tge04020   Calcium signaling pathway tge04081   Hormone signaling tge04145   Phagosome tge04371   Apelin signaling pathway tge04713   Circadian entrainment tge04730   Long-term depression tge04926   Relaxin signaling pathway tge04970   Salivary secretion tge05010   Alzheimer disease tge05014   Amyotrophic lateral sclerosis tge05022   Pathways of neurodegeneration - multiple diseases tge05410   Hypertrophic cardiomyopathy tge05412   Arrhythmogenic right ventricular cardiomyopathy tge05414   Dilated cardiomyopathy tge05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:tge00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     112634545 (NOS1)    00330 Arginine and proline metabolism     112634545 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     112634545 (NOS1)    04020 Calcium signaling pathway     112634545 (NOS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     112634545 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     112634545 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     112634545 (NOS1)   09154 Digestive system    04970 Salivary secretion     112634545 (NOS1)   09156 Nervous system    04730 Long-term depression     112634545 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     112634545 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     112634545 (NOS1)    05014 Amyotrophic lateral sclerosis     112634545 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     112634545 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     112634545 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     112634545 (NOS1)    05414 Dilated cardiomyopathy     112634545 (NOS1)    05416 Viral myocarditis     112634545 (NOS1) Enzymes [BR:tge01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      112634545 (NOS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  112634545 NCBI-ProteinID:  XP_025257905 Ensembl:  ENSTGEG00000021794 UniProt:  A0A8D2FY96 LinkDB All DBs Position 11:complement(76310432..76456230) Genome browser AA seq 1468 aa AA seqDB search MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTQPLGPPTKAVDLSHQPLAGKEQPPAVDGASGPGNGPQHAQDDGQEAGSLPHANGLAP RPPGQDPAKKAARVGLQGRGENNELLKEIEPVLNLLTSGSRGVKGGTPAKAEMKDMGIQV DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPASGKQSPTKNGSPS KCPRFLKVKNWETDVVLTDTLHLNSTLETGCTEYICMGSIMLPSQHIRRPEDVRTKEQLF PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ EERKCPEPLRFFPRKGPPLPHGDTEVHGLAAARDSQHRSYKVRFNSVSSYCDSQKSSGDG PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELT QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNHE DLVNALIERLEDAPPVNQTVKVELLEERNTALGVISNWTDEHRLPPCTIFQAFKYYLDIT TPPTPLQLQQFASLATNEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD EVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVF GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKE QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRT YEVTNRLRSESIAFIEESKKDTDEVFSS NT seq 4407 nt NT seq  +upstreamnt  +downstreamnt atggaggatcacatgttcggtgttcagcaaatccagcccaatgtcatttctgttcgtctt ttcaagcgcaaagttgggggcctgggattcctggtgaaggagcgggtcagtaagccacct gtgatcatctccgacctgattcgtgggggcgccgcggagcagagtggcctcatccaggcc ggagacatcattcttgcagtcaacggccggcccttggtggacctgagctatgacagcgcc ctggaggtactcagaggcattgcctccgagacccacgtggtcctcattctgaggggccct gaaggcttcaccacgcacctggagaccacctttacaggtgatgggacccccaaaaccatc cgggtgacacagcccctgggtccccccaccaaagctgtggatctgtcccaccagccattg gccggcaaagaacaacccccggcagtggatggggcctcgggtcctgggaatgggcctcag catgcccaagacgatgggcaggaggctggctcgctcccccatgccaacggcctggccccc aggcccccaggccaggaccctgcaaagaaagcagccagagtcggcctccaaggcagaggg gagaacaatgaactgctcaaggagatagagcctgtgctgaaccttctcaccagtgggagc agaggggtcaagggagggacacctgccaaggcagagatgaaagatatgggaatccaggtg gacagagatttggacggcaaatcacacaaacctctgcccctcggtgtggagaacgaccga gtcttcaatgacctatgggggaagggcaatgtgcctgtcgtcctcaacaacccatattca gagaaggagcagccccctgcctcaggaaaacagtcccccacaaagaatggcagcccctcc aagtgtccacgcttcctcaaagtcaagaactgggagactgacgtggttctcactgacacc ctccaccttaacagcacattggaaacgggatgcactgagtacatctgcatgggctccatc atgcttccttctcagcatatacggaggcctgaagatgtccgcacaaaagaacagctcttc cctctcgccaaagagtttattgatcaatactattcatcaattaaaagatttggctccaaa gcccacatggaaaggctggaagaggtgaacaaagagatcgaaaccactagcacctaccag ctcaaggatacagagctcatctacggggccaagcatgcctggcggaatgcctcgcgctgt gtgggcaggatccagtggtccaagctgcaggtatttgatgctcgcgactgcaccacagcc catgggatgttcaactacatctgcaaccacgtcaagtatgccaccaacaaagggaacctc aggtctgccatcaccatattcccccagaggacagacggcaagcacgacttccgagtctgg aactcccagctcatccgctacgctggctacaagcagcccgacggctccaccctgggggac ccggccaacgtgcagttcacagagatttgcatacagcagggctggaaacccccgagaggc cgctttgatgtcctgccgctcctgcttcaggccaacggcaatgaccctgagctcttccag attcctccagagctggtgttggaagttcccatcaggcaccccaagtttgagtggttcaag gacctggggctgaagtggtacggcctccctgccgtgtccaacatgctcctggagattggc ggcctggagttcagcgcctgtcccttcagtggctggtacatgggcacagagattggtgtc cgcgactactgtgacaactcccgctacaatatcctggaggaagtggccaagaagatgaac ttagacatgaggaagacgtcctcgctgtggaaggaccaggcgctggtggagatcaatatc gcggttctctatagcttccagagtgacaaagtgaccattgttgaccatcactccgccacc gagtccttcattaagcacatggagaacgagtaccgctgccggggaggctgccctgccgac tgggtgtggattgtgccccccatgtctggaagcatcacccctgtgttccaccaggagatg ctcaactaccggctcaccccctccttcgaataccagcctgatccctggaacacccacgtc tggaaaggcaccaacgggacccccacaaagcggcgagccatcggcttcaagaaactggca gaagctgtcaagttctcagccaagctgatggggcaggctatggccaagagggtcaaagca accatcctgtatgccacggagacaggcaaatcgcaagcttatgccaagaccttgtgtgag atcttcaaacacgcctttgatgccaaggtgatgtccatggaagaatatgacatcgtgcac ctggaacatgaaactctggtcctcgtggttaccagcacctttggcaacggagatccccct gagaatggggagaaatttggctgtgcgttgatggaaatgaggcaccccaactctgtgcag gaagaaaggaagtgcccggaacccttgcgtttctttccccgtaaagggcctcccctcccc catggtgacacagaagtccacggtctggctgcagcccgtgacagccagcacaggagctac aaggtccgattcaatagcgtctcctcctactgtgactcccaaaaatcatcaggcgatggg cccgacctcagagacaactttgagagtgctggacccctggccaatgtgaggttctcagtg tttggtcttggctcacgagcgtaccctcacttttgcgccttcggacatgctgtggacacc ctcctggaagaactgggaggggagaggatcctgaagatgagggaaggggatgagctctgt gggcaggaagaggctttcaggacctgggccaagaaggtcttcaaggcagcctgtgatgtc ttctgtgtgggagatgatgtcaacattgaaaaggcgaacaattccctcatcagcaatgac cgcagctggaagagaaacaagttccgcctcacctatgtggccgaagctccagaactcacg caaggtctatccaatgtccacaaaaagcgagtctcagctgcccgactccttagccgtcaa aacctccagagccctaaatccagtcggtcaactatcttcgtgcgtctccacaccaacggg aatcaggagctgcagtaccagcctggggaccacctgggcgtcttccctggcaaccacgag gacctcgtgaatgccctgatcgagcggctggaagacgcaccccctgtcaaccagacggtg aaagtggaactgctggaggagcggaacacggctttaggcgtcatcagtaactggacagac gagcaccgcctcccaccctgcaccatcttccaggccttcaagtactacctggacatcacc acgccaccaacgcccctgcagctgcagcagtttgcctccctagccaccaatgagaaggag aagcagcgtctgctggtcctcagcaagggtttgcaggagtatgaggaatggaaatggggc aagaaccccaccatcgtggaggtgctggaggagttcccatccatccagatgccggccacc ctgctcctgacccagctgtccctgctgcagccccgctactattccatcagctcctcccca gacatgtaccctgatgaagtgcacctcactgtggccatcgtttcctaccgcactcgagat ggagaaggaccaattcaccacggcgtgtgctcctcctggctcaaccggatacaggctgac gaagtggtcccctgtttcgtgagaggagcacccagcttccacctgccccggaacccccaa gtcccctgcatcctcgttggaccgggcaccggcattgcacctttccgaagcttctggcaa cagcggcaatttgatatccaacacaaaggaatgaacccctgccccatggtcctggtcttc gggtgccggcaatccaagatagatcatatctacagggaagagaccctgcaggccaagaac aagggggtcttcagagagctgtacacggcttactcccgggagccagacaaaccaaagaag tacgtgcaggacatcctgcaggagcagctggcggagtctgtgtaccgagccctgaaggag caagggggccacatttacgtctgtggggacgtcaccatggccgctgatgtcctcaaagcc atccagcgcatcatgacccagcaggggaagctctcggcagaggacgccggcgtgttcatc agtcggatgagggatgacaaccggtaccacgaggatattttcggagtcaccctgcgaacg tatgaagtgaccaaccgccttagatctgagtccattgccttcattgaagagagcaaaaaa gacaccgatgaggttttcagctcctaa

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