Theropithecus gelada (gelada): 112634796
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Entry
112634796 CDS
T08041
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00260
Glycine, serine and threonine metabolism
tge00630
Glyoxylate and dicarboxylate metabolism
tge00670
One carbon pool by folate
tge01100
Metabolic pathways
tge01200
Carbon metabolism
tge01230
Biosynthesis of amino acids
tge01240
Biosynthesis of cofactors
tge01523
Antifolate resistance
tge04981
Folate transport and metabolism
Module
tge_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
112634796 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
112634796 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
112634796 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
112634796 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112634796 (SHMT2)
Enzymes [BR:
tge01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
112634796 (SHMT2)
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
112634796
NCBI-ProteinID:
XP_025258401
Ensembl:
ENSTGEG00000015795
LinkDB
All DBs
Position
11:16289009..16294626
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AA seq
513 aa
AA seq
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MSGVLGLASQAEPFRAALSPADDATEPHCLRQTGVPAAVRAGRRWNGLCRDGGSWSGWPF
GLSTARQPRLRLGKQTGAGQARRACRTVILRCGSCCRGRRTGSVVAWSSLPQRYYGGAEV
VDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGH
LTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARL
IDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIF
YRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYS
LQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNT
CPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKTAKLQDFKSF
LLKDSETSQRLADLRQRVEQFARGFPMPGFDEH
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgagtggagttctcggcctggcctcacaagctgagccttttcgggcagctctgagccct
gcagatgatgcaaccgagcctcactgcttgcgtcagacaggggtcccggcggcagtgagg
gctggaaggaggtggaacggcctctgcagagatgggggcagctggtcaggatggccattc
gggctcagcacagcaaggcagcccagactcagactggggaagcaaacaggggctggacag
gccaggagagcctgtcggacagtgatcctgagatgtgggagttgctgcagagggagaagg
acaggcagtgtcgtggcctggagctcattgcctcagagatattatgggggagcagaggtg
gtggatgaaattgagctgctgtgccagcgccgggccttggaagcctttgacctggatcct
gcacagtggggagtcaatgtccagccctactctgggtccccagccaacctggctgtctat
acagcccttctgcaacctcatgaccggatcatggggctggacctgcccgatgggggccat
ctcacccacggctacatgtctgacgtcaagcggatatcagccacgtccatcttcttcgag
tctatgccctataagctcaatcccaaaactggcctcattgactatgaccagctggcactg
actgctcgacttttccgaccgcggctcatcatagctggcaccagcgcctatgctcgcctc
attgactatgcccgcatgagagaggtgtgtgatgaagtcaaagcacacctgctggcagac
atggctcacatcagtggcctggtggctgccaaggtgattccctcgcctttcaagcacgcg
gacatcgtcaccaccactactcacaagactcttcgaggggccaggtcagggctcatcttt
taccggaaaggggtgaaggctgtggaccccaagactggccgggagatcccttacacattt
gaggaccgaatcaactttgctgtgttcccatccctgcaggggggcccccacaatcatgcc
attgctgcagtagctgtggccctaaagcaggcttgcacccccatgttccgggagtactcc
ctgcaggttctgaagaatgctcgggccatggcggatgccctgctagagcgaggctactca
ctagtatcaggtggtactgacaatcacctggtgctggtggacctgcggcccaagggcctg
gatggagctcgggctgagcgggtgctggagcttgtatccatcactgccaacaagaacacc
tgtcctggagaccgaagtgccatcacaccggggggcctgcggcttggggccccggccttg
acttctcgacagttccgtgaggatgacttccggagagttgtggactttatagatgaaggg
gtcaacattggcttagaggtgaagaccaagactgccaagctccaggatttcaaatccttc
ctgctcaaggactcagaaacaagtcagcgtctggccgacctcaggcaacgggtggagcag
tttgccaggggcttccccatgcctggttttgatgagcattga
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