Theropithecus gelada (gelada): 112635149 Help Entry 112635149         CDS       T08041                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase type 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism tge  Theropithecus gelada (gelada) Pathway tge00230   Purine metabolism tge01100   Metabolic pathways tge01522   Endocrine resistance tge04015   Rap1 signaling pathway tge04022   cGMP-PKG signaling pathway tge04024   cAMP signaling pathway tge04062   Chemokine signaling pathway tge04072   Phospholipase D signaling pathway tge04081   Hormone signaling tge04082   Neuroactive ligand signaling tge04114   Oocyte meiosis tge04211   Longevity regulating pathway tge04213   Longevity regulating pathway - multiple species tge04261   Adrenergic signaling in cardiomyocytes tge04270   Vascular smooth muscle contraction tge04371   Apelin signaling pathway tge04540   Gap junction tge04611   Platelet activation tge04713   Circadian entrainment tge04714   Thermogenesis tge04723   Retrograde endocannabinoid signaling tge04724   Glutamatergic synapse tge04725   Cholinergic synapse tge04727   GABAergic synapse tge04742   Taste transduction tge04750   Inflammatory mediator regulation of TRP channels tge04911   Insulin secretion tge04912   GnRH signaling pathway tge04913   Ovarian steroidogenesis tge04914   Progesterone-mediated oocyte maturation tge04915   Estrogen signaling pathway tge04916   Melanogenesis tge04918   Thyroid hormone synthesis tge04921   Oxytocin signaling pathway tge04923   Regulation of lipolysis in adipocytes tge04924   Renin secretion tge04925   Aldosterone synthesis and secretion tge04926   Relaxin signaling pathway tge04927   Cortisol synthesis and secretion tge04928   Parathyroid hormone synthesis, secretion and action tge04934   Cushing syndrome tge04935   Growth hormone synthesis, secretion and action tge04961   Endocrine and other factor-regulated calcium reabsorption tge04962   Vasopressin-regulated water reabsorption tge04970   Salivary secretion tge04971   Gastric acid secretion tge04972   Pancreatic secretion tge04976   Bile secretion tge05032   Morphine addiction tge05163   Human cytomegalovirus infection tge05166   Human T-cell leukemia virus 1 infection tge05200   Pathways in cancer tge05207   Chemical carcinogenesis - receptor activation tge05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:tge00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     112635149 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     112635149 (ADCY6)    04371 Apelin signaling pathway     112635149 (ADCY6)    04072 Phospholipase D signaling pathway     112635149 (ADCY6)    04024 cAMP signaling pathway     112635149 (ADCY6)    04022 cGMP-PKG signaling pathway     112635149 (ADCY6)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     112635149 (ADCY6)    04081 Hormone signaling     112635149 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     112635149 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     112635149 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112635149 (ADCY6)    04062 Chemokine signaling pathway     112635149 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     112635149 (ADCY6)    04923 Regulation of lipolysis in adipocytes     112635149 (ADCY6)    04912 GnRH signaling pathway     112635149 (ADCY6)    04913 Ovarian steroidogenesis     112635149 (ADCY6)    04915 Estrogen signaling pathway     112635149 (ADCY6)    04914 Progesterone-mediated oocyte maturation     112635149 (ADCY6)    04921 Oxytocin signaling pathway     112635149 (ADCY6)    04926 Relaxin signaling pathway     112635149 (ADCY6)    04935 Growth hormone synthesis, secretion and action     112635149 (ADCY6)    04918 Thyroid hormone synthesis     112635149 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     112635149 (ADCY6)    04916 Melanogenesis     112635149 (ADCY6)    04924 Renin secretion     112635149 (ADCY6)    04925 Aldosterone synthesis and secretion     112635149 (ADCY6)    04927 Cortisol synthesis and secretion     112635149 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     112635149 (ADCY6)    04270 Vascular smooth muscle contraction     112635149 (ADCY6)   09154 Digestive system    04970 Salivary secretion     112635149 (ADCY6)    04971 Gastric acid secretion     112635149 (ADCY6)    04972 Pancreatic secretion     112635149 (ADCY6)    04976 Bile secretion     112635149 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     112635149 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     112635149 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     112635149 (ADCY6)    04727 GABAergic synapse     112635149 (ADCY6)    04725 Cholinergic synapse     112635149 (ADCY6)    04723 Retrograde endocannabinoid signaling     112635149 (ADCY6)   09157 Sensory system    04742 Taste transduction     112635149 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     112635149 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     112635149 (ADCY6)    04213 Longevity regulating pathway - multiple species     112635149 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     112635149 (ADCY6)    04714 Thermogenesis     112635149 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112635149 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     112635149 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112635149 (ADCY6)    05163 Human cytomegalovirus infection     112635149 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     112635149 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     112635149 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     112635149 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     112635149 (ADCY6) Enzymes [BR:tge01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      112635149 (ADCY6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  112635149 NCBI-ProteinID:  XP_025258876 Ensembl:  ENSTGEG00000000457 UniProt:  A0A8D2E5E6 LinkDB All DBs Position 11:complement(7923867..7947627) Genome browser AA seq 1168 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRSRRCGTRAGGFCTPRYMSCLRDAEPPSPTPAGP PRCPWQDDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTVGGTAEVAPDAVPRSGRSCWR RLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPTRPQPAY VALLACAAALFLGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGSALAADPRSPSAGLW CPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDAFLWKQLGANVLLFLCTN VIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINT KKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHC LRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRV HCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNA YLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFR QMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEKK YSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSILMLGIYASIFLLLLVTVLTCAVYSC GSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRTCAARMLNLT PADITACHLQQLNYSLGLDAPLCEGTMPTCSFPEYFIGSVLLSLLASSVFLHISSIGKLA MVFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPV ILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHF LARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIIS EERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNN FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKG YQLECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3507 nt NT seq  +upstreamnt  +downstreamnt atgtcatggtttagtggcctcctggtccctaaagtggatgaacggaaaacagcctggggt gaacgcaatgggcagaagcgttcacggcgctgtggcactcgggcaggtggcttctgcacg ccccgctatatgagctgcctccgggatgcagagccacccagccccacccctgcgggcccc cctcggtgcccctggcaggatgacgccttcatccggaggggcggcccgggcaagggcaag gagctggggctgcgggcagtggccctgggcttcgaggacacagaggtgacaacgacagtg ggcgggacagctgaggtggcgcccgacgcggtgcccaggagtgggcgatcctgctggcgc cgtctggtgcaggtgttccagtcgaagcagttccgttcggccaagctggagcgcctgtac cagcgatacttcttccagatgaaccagagcagcctgacgctgctgatggcggtgctggtg ctgctcacggcggtgctgctggctttccatgcggcgcccacccgccctcagcctgcctat gtggccctgctggcctgcgccgccgccctgttcctggggctcatggtggtgtgtaaccgg catagcttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcg gcagtgcaggtcgggagtgccctcgcagcagacccacgaagcccctctgcgggcctctgg tgccctgtgttcttcgtctacatcgcctacacgctcctccccatccgcatgcgggctgcg gtcctcagcggcctgggcctctccaccctgcatttgatcttggcctggcaacttaaccgt ggtgatgccttcctctggaagcagctcggtgccaatgtgctgctgttcctctgcaccaac gtcattggcatctgcacacactatccagcagaggtgtctcagcgccaggcctttcaggag acccgtggttacatccaggcccggctccacctgcagcatgagaatcggcagcaggagcgg ctgctgctgtcggtgttgccccagcatgttgccatggagatgaaagaagacatcaacaca aaaaaagaagacatgatgttccacaaaatctacatacagaagcatgacaatgtcagcatc ctgtttgcagacattgagggcttcaccagcctggcatcccagtgcactgcacaggagctg gtcatgaccctgaatgagctctttgcccggtttgacaagctggctgcggagaatcactgc ctgaggatcaagatcttgggggactgttactactgtgtgtcagggctgccggaggcccgg gccgaccatgcccactgctgtgtggagatgggggtagacatgatcgaggccatctcgctg gtacgtgaggtgacaggtgtgaatgtgaacatgcgcgtgggcatccacagcgggcgcgtg cactgcggcgtccttggcttgcggaaatggcagttcgatgtgtggtccaatgatgtgacc ctggccaaccacatggaggcaggaggccgggctggccgcatccacatcactcgggcaaca ctgcagtacctgaatggggactacgaggtggagccaggccgtggtggcgagcgcaacgca tacctcaaggagcagcacattgagactttcctcatcctgggcgccagccagaaacggaaa gaggagaaggccatgctggccaagctgcagcggactcgggccaactccatggaagggctg atgccgcgctgggtgcctgatcgtgccttctcccggaccaaggactccaaggccttccgc cagatgggcattgatgattccagcaaagacaaccggggcacccaagatgccctgaaccct gaggatgaggtggatgagttcctgagccgtgccatcgatgcccgcagcattgatcagctg cggaaggaccatgtgcgccggtttctgctcaccttccagagagaggatcttgagaagaag tactcccggaaggtggatccccgcttcggagcctacgttgcctgtgccctgttggtcttc tgcttcatctgcttcatccagcttctcatcttcccacactccatcctgatgcttgggatc tatgccagcatcttcctgctgctgctggtcaccgtgctgacctgtgccgtgtactcctgt ggttctctgttccctaaggccctgcaacgtctgtcccgcagcatcgttcgctcacgggca catagcaccgcagttggcatcttttccgtcctgcttgtgtttacttctgccattgccaac atgttcacctgtaatcacacccctatacggacctgtgcagcccggatgctgaatttaaca cctgctgacatcactgcctgccacctgcagcagctcaattactctctgggcctggatgct cccctgtgtgagggcaccatgcccacctgcagcttccctgagtacttcatcgggagcgtg ctgctgagtctcttggccagctctgtcttcctgcacatcagcagcatcgggaagttggcc atggtctttgtcttggggctcatctatttggtgctgcttctgctgggtcccccagccacc atctttgacaactatgacctactgcttggcgtccatggcttggcttcttccaatgagacc tttgatgggctggactgtccagctgcagggagggtggccctcaaatatatgacccctgtg attctgctggtgtttgcgctggcgctgtatctgcatgctcagcaggtggagtcgactgcc cgcctagacttcctctggaaactacaggcaacaggggagaaggaggagatggaggagcta caggcatacaaccggaggctgctgcataacattctgcccaaggacgtggccgcccacttc ctggcccgggagcgccgcaatgatgaactctactatcagtcgtgtgagtgtgtggctgtt atgtttgcctccattgccaacttctctgagttctatgtggagctggaggcaaacaatgag ggtgtcgagtgcctgcggctgctcaacgagatcatcgctgactttgatgagatcatcagc gaggagcggttccggcagctggaaaagatcaagacaattggtagcacctacatggctgcc tcagggctgaacgccagcacctacgatcaggtgggccgctcccacatcactgccctggct gactatgccatgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaat ttccagatgaagattgggctgaatatgggcccagtcgtggcaggtgtcatcggggctcgg aagccgcagtatgacatctgggggaacacagtgaatgtctctagtcgtatggacagcacg ggggtccccgaccgaatccaggtgaccacggacctgtaccaggttctagctgccaagggc taccagctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctac ttcctcaatgggggccccagcagttag

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