Theropithecus gelada (gelada): 112635915
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Entry
112635915 CDS
T08041
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00020
Citrate cycle (TCA cycle)
tge00480
Glutathione metabolism
tge01100
Metabolic pathways
tge01200
Carbon metabolism
tge01210
2-Oxocarboxylic acid metabolism
tge01230
Biosynthesis of amino acids
tge04146
Peroxisome
tge05230
Central carbon metabolism in cancer
Module
tge_M00009
Citrate cycle (TCA cycle, Krebs cycle)
tge_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
112635915 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
112635915 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
112635915 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
112635915 (IDH1)
Enzymes [BR:
tge01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
112635915 (IDH1)
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
XRN1_D2_D3
Motif
Other DBs
NCBI-GeneID:
112635915
NCBI-ProteinID:
XP_025259788
Ensembl:
ENSTGEG00000004747
UniProt:
A0A8D2EGQ0
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Position
12:complement(85021194..85040786)
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AA seq
414 aa
AA seq
DB search
MSKKIGGGSVVELQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaaaaaatcggtggcggttctgtggtagagctgcaaggagatgaaatgacacga
atcatttgggaattgattaaagagaaactcatttttccctatgtggaattggatctacat
agctatgatttaggcatagagaatcgtgatgccaccaacgaccaggtcaccaaggatgct
gcagaagctataaagaagtataatgttggcgtcaaatgtgccactatcactcctgatgag
aagagggttgaggagttcaagttgaaacaaatgtggaaatcaccaaatggcaccatacga
aatattctgggtggcacggtcttcagagaagccattatctgcaaaaatatcccccggctt
gtgagtggatgggtaaaacctatcatcataggtcgtcatgcttatggggatcaatacaga
gcaactgattttgttgttcctgggcctggaaaagtagagataacctacacaccaagtgat
ggaacccaaaaggtgacatacctggtacataactttgaagagggtggtggtgttgccatg
gggatgtataatcaagataagtcaattgaagattttgcacacagttccttccaaatggct
ctgtctaagggttggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat
gggcgttttaaagacatctttcaggagatatatgacaagcagtacaagtcccaatttgaa
gcccaaaagatctggtatgagcataggcttatcgatgacatggtggcccaagctatgaaa
tcagagggaggcttcatctgggcctgtaaaaactatgatggtgacgtgcagtcggactct
gtggcccaagggtatggctctctcggcatgatgaccagtgtgctggtttgtccagatggc
aagacagtagaagcagaggctgcccacgggactgtaacccgtcactaccgcatgtaccag
aaaggacaggagacgtccaccaatcccattgcttccatttttgcctggaccagagggtta
gcccacagagcaaagcttgataacaataaagaacttgccttctttgcaaatgctttggaa
gaagtctgtattgagacaattgaggctggcttcatgaccaaggacttggccgcttgcatt
aaaggtttacccaatgtgcaacgttctgactacttgaatacatttgagttcatggacaaa
cttggagaaaacttgaagatcaaactagctcaggccaaactttaa
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