| Entry |
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| Symbol |
ARHGEF12
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| Name |
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
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| KO |
| K07532 | Rho guanine nucleotide exchange factor 12 |
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| Organism |
tgu Taeniopygia guttata (zebra finch)
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| Pathway |
| tgu04270 | Vascular smooth muscle contraction |
| tgu04625 | C-type lectin receptor signaling pathway |
| tgu04810 | Regulation of actin cytoskeleton |
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| Brite |
KEGG Orthology (KO) [BR:tgu00001]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
100222469 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
100222469 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100222469 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:tgu04131]
100222469 (ARHGEF12)
Membrane trafficking [BR:tgu04131]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
100222469 (ARHGEF12)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
24:complement(4953606..5035725)
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| AA seq |
1539 aa
MSGTQSTITDRFPLKKPSRHGSILSRESPADKKQKVERCSSTHDFDPTDSSSKKTKSSSE
ESRSETYGLVQRCVVIQRDENGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNG
TLVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSDVDLAAFGHMSPIMASPHSP
GTSGNAERITSPVLMGEENNIVHSQKVEILRKMLQKEQERLQILQEEYSRAPSTRLLKEI
QEAKKHIPQLQEQLSKATGCTQDGVLSSRSVSESLQISEGEAESGDSGSKLDFSGDSPSR
PNSDIADSPRSGLKERIYPDESPEKAELQDTDSQSSVGSPLSRVGTQIIGAEDDDFDTEQ
EQINGQCSCFQNIELLKSRPAHLAVLLHHVVSQFDPAALLCYLYTDLYKQTNSKETRRVF
LEFYQFFLDRAANLKVPVPEEISLELDRRRPELLPEELHRQFIQTMQDKVCPEVQRNLED
FRQKRSMGLTLAEGELTRLDAERLRDRNAVEKERSCAEQILAKIEEVLMTSQPLEEDKSS
TMQYVILTYMKHLGVKVKEPRNLEQKRGRIGFLPKIKQSIKKEKEGEEKGKRRGFPNILG
PPRRPSRHDSSAIGRAMEMQKPRHPKHSPTASSVSPEPPESSKMRQSGSSSDGTDAPYPP
ANPMSPLATGPFASPEGSKDSDTGVKQPGEAPPASDSMDGTPRTPNNTFEFPSPLENLQE
EEGESERMVDMGTPKPFRKMDSVGFADVQSEDELYDFDMDMDPPNWQQLVSREVLMGLKP
YEIKRQEVINELFYTERAHVRTLKVLHNVFYQRVTREGILSSSDKRKIFSNLEDILGLHV
ALNDQMKSVRKRNETSVIGQIGEDLLSWFSGAAEEKLKLATATFCSNQPFALEVIKSRQK
KDSRFQTFVQDAESNPLCRRLQLKDIIPTEMQRLTKYPLLLDNIAKYTELPEEKEKVKKA
ADHCRQILNHVNQAVKESENKQHLEDYQRRLDLSYLKQSEDPMMDEFRNLDLTKRKMLHE
GPLTWKVNRDKTIDLYTLLLEDILVLLQKQDDKLVLKCHSKILASTADSKHTFSPIIKLN
TVLVRQVATDNKAFFVISMSATGAHIYELVAQTVSEKNVWQDLIAQMAGTVKMGSSRRVI
PLPQSGPGEEEREEEEQQKLKEQHGIPASSLQSPDKDLGLESPLILNPQSSSPIMSEKAK
VEGLLGAEAQFEKVQQAELALKDSSACYEHPASSSASVPEGQWARDALRNLGLLRQLLVQ
QLGLAEKGPLEDRQRSPRFRTVSQEAQTESGTELQPPESKFQQPGEDGSLGRTGAAAGGH
GARTAAECPGTEPAARGALPMDSTNLEGSSSELEGLGAEESGERFFDAREAHSDENPGES
ESELLGRKEEEEEEEEEEEEEVQIRISGNYLILDGYGAVQESSTDEEVSALVLQCTSHQQ
PPLDCAQQQQQQPLSPRDARSDGGSSPFPEELRWPGLEEPCPFLGSPQLPLQIRVQLMQY
IHNIEDALEKLKEVEEDYSVLRRQGLAGSASTGEHSDKS |
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| NT seq |
4620 nt +upstreamnt +downstreamnt
atgagtggcacacagtccacaatcacggacaggtttcctctcaaaaaaccttcgagacac
ggcagcattctgagcagagagtctccagcagacaagaagcagaaggtcgaacgctgcagc
agcacccacgacttcgatcccacagatagctcctccaagaagacaaagtctagttctgag
gagagtagatccgagacgtatggcctggtgcagaggtgtgtggtgatccagcgggatgag
aacggcttcgggctgacggtcagcggggacaaccccgtcttcgtgcagtccgtcaaggaa
gatggagcagccatgcgggctggagtgcagacaggtgatagaattatcaaggtgaatggg
actctggtaacacactcgaaccatttggaggtggtcaagctgatcaagtcgggttcctat
gtagctctcactgtccaggggcgccctccagggtcgccccagattcccttggcggattcc
gacgtggatctggcagcttttgggcatatgtctcccatcatggcatccccccactcgcct
ggcacgtcagggaatgcagaaaggatcaccagccccgtgctcatgggggaggagaataac
attgtccacagccagaaggtggagattctgaggaagatgctccagaaggagcaggagagg
ctgcagatcctgcaggaggagtacagccgagccccctccacccgcctgctcaaggagatc
caggaggcaaagaaacacattcctcagctgcaggagcagctgtccaaggccacgggctgc
actcaggatggagtcctgtcctccaggtctgtgtcagagtcactgcagatcagcgagggc
gaggcagagagtggggacagtggcagcaaactggatttcagtggtgacagcccctccaga
cccaacagtgacattgctgatagccctcgcagtggcctgaaggagaggatttatccagat
gagagcccagaaaaggctgagcttcaagacactgactcccagtccagtgttggcagtccc
ctgtcccgagtggggactcagatcattggagcagaggatgatgattttgacacggagcag
gagcagattaatgggcagtgcagctgcttccagaacatcgagctcctgaaatcccgtcct
gctcacctggctgtcctcctgcaccacgtggtgtcccagtttgatcctgcagcactgctg
tgctacctttacacagacctgtacaaacagaccaactccaaagagacccggcgtgttttc
ctggagttttaccagtttttcctggacagagctgcaaacctgaaagtcccagttccagag
gaaatctccttggaattagacaggagaaggccagagctcctccctgaagagctgcaccgc
cagttcatccaaaccatgcaggataaagtctgtccagaggttcagaggaacctggaagat
ttcaggcagaagaggagcatggggctgaccctggccgagggggagctgaccaggctggac
gcggagcggctccgcgaccgcaacgccgtggagaaggagaggagctgtgcagagcagatc
ctggccaaaatcgaggaggtcctgatgacatctcagcctctggaagaagacaagagctcc
acgatgcaatatgtgatcctcacctacatgaaacacctgggagtgaaagtcaaagagcct
cggaacctggagcagaagcggggccggattggtttcctgccaaaaatcaagcaaagcatc
aagaaagagaaagaaggagaggagaaagggaagaggagaggcttccccaacatcctgggg
cccccaaggagaccaagccgacatgacagcagtgcaattggcagggccatggagatgcag
aagcccaggcaccccaagcactcgcccacagcctcctctgtgagcccagagccccccgag
tccagcaagatgcgccagagcggctcctccagcgatggcactgatgccccttacccccct
gccaaccccatgtcccccctggccacggggcctttcgcctctccagagggcagcaaggac
agtgacacaggtgtgaagcagcctggggaagccccacctgccagtgactccatggatggc
accccccgcacacccaacaacacctttgagttcccatctcctctggaaaacctgcaggag
gaggagggagagtctgagaggatggttgacatgggaacgccgaagcctttccgcaagatg
gacagtgttggctttgcagatgtgcagagtgaggatgagctctatgacttcgacatggac
atggaccctcccaactggcagcagcttgtgagcagggaggtgctgatggggctcaaaccc
tacgaaatcaaacgtcaagaagtgataaatgagctgttctacaccgagcgagcccacgtg
cgcacgctgaaggtcctgcacaacgtcttctaccagagggtcaccagggagggcatcctc
agctccagtgacaagcggaaaatcttctccaacctggaggacatccttgggctgcacgtt
gcactgaacgatcagatgaaatctgtccgaaaaaggaacgagacttctgtcattggccaa
attggggaagatttgctctcctggtttagtggagcagcagaggagaagctgaaacttgcc
actgccaccttctgcagcaaccagcccttcgctctcgaggtcatcaagtcccgccagaag
aaggactcgcgcttccagaccttcgtgcaggatgctgagagcaatcccctgtgccggcgg
ctgcagctgaaggatatcatccccacagagatgcagaggttgactaaatacccccttctg
ctggataacattgctaaatacacagagctgcctgaggagaaggagaaagtcaagaaagca
gcagatcactgtcgccagatcctcaaccacgtgaaccaggctgtcaaagagtcggagaac
aagcagcatttggaggattatcagcgcagactcgacctctcctacttgaagcagtcagag
gatcccatgatggatgagttcaggaacctggatctaacaaagagaaagatgctccatgaa
gggcccctgacctggaaggtgaatcgtgacaaaaccatcgatctgtacactctgctgctg
gaggacatcctggtgctgctgcagaaacaagatgacaaactggtgctgaagtgccacagc
aagatcctggcatccacagctgacagcaaacacaccttcagccccatcatcaaactcaac
actgtgctggttcgccaggtggccacagataacaaagctttcttcgtcatctccatgtcg
gcgacgggggctcacatctacgagctggtggcacagactgtctcagagaagaatgtctgg
caggaccttatagctcagatggcaggaactgtgaagatggggagcagcagaagagtgatc
ccactgcctcagtcgggccctggcgaagaggagcgtgaggaagaggagcagcagaagctc
aaagagcagcatggcattcctgccagcagcctgcagagtccagataaagatttgggcctg
gagtctccgttgatactgaaccctcagtcctcttcacccatcatgtctgaaaaggccaag
gtggaagggctgctgggggctgaggcacagtttgagaaggtgcagcaggcagagctggca
ctgaaggactcctctgcctgctatgagcacccagccagcagctcagcctcggtgccagag
gggcagtgggcacgggatgccctgaggaacttggggctgctgaggcagctcctggtgcag
cagctgggcctggccgagaagggacccctggaggacagacagcgctcgcccaggttcagg
accgtgtcccaggaagcccagacagagagtggcaccgagctgcagcctccagagagcaaa
ttccagcagcctggagaggacgggagcctcggcagaactggggcggccgcgggcgggcac
ggcgcccggactgccgccgagtgcccgggcaccgagcccgctgccaggggcgctttgccc
atggacagcacgaacctggagggctccagctcggagctggaggggctgggggctgaggag
agcggggagcggttcttcgatgcccgggaagctcacagcgacgagaaccccggcgagagt
gagagcgagctgctgggcaggaaggaggaggaggaggaggaggaagaggaggaggaggag
gaggtgcagattcggatctcaggaaattatttgatcctcgatggctacggagcagtgcag
gagagctccacggacgaggaggtgtcagccctggtcctgcagtgcacctcccaccagcag
ccccccctggactgtgcccagcagcagcagcagcagcccctgtccccccgggacgcgcgc
tcggacgggggcagctcgcccttccccgaggagctgcgctggccggggctggaggagccc
tgccccttcctgggcagccctcagctcccgctgcagatccgagtgcagctcatgcagtac
atccacaacatcgaggatgccctggagaagctgaaggaggttgaggaggattacagcgtt
ctgcggcgccaggggctggctggctcagcctccacaggagagcactcagacaaaagctag |
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