Taeniopygia guttata (zebra finch): 100227700 Help Entry 100227700         CDS       T01082                                  Symbol SYNE2 Name (RefSeq) nesprin-2 isoform X1   KO K19346   nesprin-2 Organism tgu  Taeniopygia guttata (zebra finch) Pathway tgu04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:tgu00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     100227700 (SYNE2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:tgu03036]     100227700 (SYNE2) Chromosome and associated proteins [BR:tgu03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     100227700 (SYNE2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin_SYNE1 CH KASH Spectrin SYNE1 ATG17_like Motif Other DBs NCBI-GeneID:  100227700 NCBI-ProteinID:  XP_030131007 LinkDB All DBs Position 5:complement(55024965..55200972) Genome browser AA seq 6998 aa AA seqDB search MASEQSSASTEEQASSEIDDLHLTLQVQREFTQKKTFTSWINSILAKHTPPYVVSDLYTD IQQGHLLLDLLEVLSGQHLPREKGFNTFQCRSNIENALTFLKSRSLKLINIHVADIIEGK PSIVLGLIWTIIFHFHIEELARTLACTYNQPSPDYPSAVDSSPKANRSAKKSAKIKERWK MSATKALLLWAKEQCSLHGSVSVTDFKSSWRSGLAFLAIIQTLRPGLVDLEKAKARSNKE NLREAFRIAELELNIPRLLEPEDVDTVNPDEKSIMTYVAQFLQYSKNLPESEEDMQEKVR EAVGWLAEQEKKLAKLLVETEDETYCQKYKEMMSFMETFNQEKIPFLPVLSSKRGEAELS GGQQQMREEWDKVISQMNEWKVKLDQMLPSPLGSIEAWLQEVERLQAEDLPDLQDPFKAM SVFREIIVIFKGLMECFDSHLDTLQSFKNEDEKNMPLVLPEKLEEMKRRFGNIRSTNPST FLEYHYGLCSAIANEVKLKLNIWDVKYGAKESVESLLENWNNFIEEKKLETQLDIATHIC EDLKNISGPGLAGDPQEISKLLKTVESKISTCKEYISNVNTTLQKVLSSWRNYTENIHLL KTWLEENRNEDPKEIPAEILAKRNLIHGSLNEAGNHLIEVSKEQVGSNIAKELKKLNRRW AKFMKRTHFLGEESTNAAEKTTEFPGSLEKVEELLGGVDSWAAEMGRVLSKISHEEPVEP EMEEHLQSWAARGSSCLDQVVAAEKILHSLRQNVSSQVFQQHSHTTELEARIKEARDKVE AVMGDLNNILSKSEKRPSEKEALLNFEESQKELEASISKAVQLVSQKLSPEGCISRYEEA FNALDNKVLDKFLKAAELLKNISSDHEKLVVEDDVRRRWEAARQEIVSYVQLIVEREKKK FNATLKKINKQLGKEKKLLSMDKTKGLIKEHEAFFSHEGSMKELNKSLEDLKTLARLSEE TVPGIQTLTADCEKRLEKVQQMVADTYTALLARLGKGQSPQKGSSIMASENGEESGSSQE VDSLMVQETSRPAADAVLEPDVNHHNGESCADKLEEDGDSAVPALLESFNTQRSNLEELL RLCRDKVASDFTDEIKGTSCLNFKVTELEAMLDLEISSGWKQLENISSTLENLVSEVQQA ALSEARNKLQSEWKEIQDIISIRVNSLRAAMEIVCETESKSIFVCRLVDEWLKKKYIHQF SLMDNDLPDSELKMLQRSILKQIEECKQLEHLDSSAGDEVNPLDLQAARKVLINCQNQLE EMGHKMQMREAVLKDLEAFMASLRKIQSSISCLPNPPDQPEMQGKALREAAQEVSHMAEE AKCLDEHLKGVNVCLEDADSGRKTWCEQLVQTLSKKLNAIYDTPSEQVPTEEKDLYRTFS KKSSELLKNVQDLRDRINKLGLKDPTIPAIQKRIKSLTELEKELDRAAAEMKSMHEIANK LPQINEEKAEEANEQCRVTERLWEDTKLLLAECQEQCARALELLKQYQSCKTSLTSIIQK QEVVLSQQTSYMGKENLNRLIAKIEEAKEEFNDHSEDVDRINQICKNLQFQLNKMRSFEE PPFENEANIIVDRWLDINEKTENYCDNLGRAQALWDKLLNLSGTIEAWANAELKNAEDHC LTEEDLTQLKACLRVQEQKLQKFDSTVAEIEELLNSNEPPLELQVIRSSVVQKMELIKEL LSAKRGTSELTVNAAELKGDLDLAKTQIGMTESLLKALSPSDTLEIFTKLEEIHQKILQQ EHLVALLQEETDCPDVDELNKQLKCVTDLFNSKKHVLQDHFMGVLDRQCKNFNDWFSSTQ LSLKDCFEPSETKSILEERLQRLKRFLTSEGRDRDTQEVKALLNKVKPYLPKASIKHLSS RVRDQEAELQRLISKCQKREKELGASLQQLSSLEESSMALEEWLSAQEGKVKGINKDDTE LEDVYKTLLMQRKPFDSLAQLSNSLGEAGLTEYETLSEASNLISRYHALITRVSEMAGNT ERLPVEGQHFEDLAQDVSCWIKKLEEALNQMRSQGSELPSDERINQIKAITSLRDDGEAK IKSMLALGDAVLRNEKNKKPEVQQAISELQKKWESVCQLATEYSSPEEQLQCNREQYEQS KEDLKQALMELEKQQQEIFALQPGLEEKQAQLANYADLLQKTEALTSQFSKLKSQKEHLQ GHTVDPCFTEAEWSELKHQHENLLGQLQTMMQTLESPVQEHQQVQDITTGLSTELKTLSE KLAECDGPAMEEPSAEQNQLKSQEQQGPLSRCEDAVKKSLVLAETVKQNTSSPEQEFIKD EMETLQSEHKERLEERLENVKQKKENIFSEALELKDEFGNAIQKEDKADAMLKRETQITS DTPISAEETPTAVELKEPLEMSDGQDVNGNMSEEERQNAPVLEESSVPSDSPLQDIHHSR DRLGKAVQGETDKESPDMDRPDRFQEDVLDSAVLGGEADLERHQDGVVIEGDESREKTHP AQEEPSDVENQSYREDGGQVQQKLCQKGQILESAAADEKDGLGSNPPVPAHEDTGAEVVV QKELFPRVQVNNEYFEEEQKVNELKNEVAELDMVLINEQLKELENLKTELETWKAKSVCH GEETIPNGTGSNGAELQTTEPCWDRLLQELEAVKAVKQQQCCLINEYQKNLSAAQSSMKN LSTEKDNIKMGPMNNTVLLEKIKACIESLRKERDVLNQLQSQQEVLSQHLTCMDKVLTES QMRQLEHWWQHMEQAVQKKHDQVVAEIDEFNLLMNKARDIQRLIQEQYLQAELHSSAAGK AKDPLIWTTELQDIKHGLSLLKRKIELQMKRIWSDQEKVALENSIQDLQGKLEELSAQQT SQEDIQTTGPALMKHEMMKRLKENISWVKDSLSHLDQKAALFPSDVKSQIRNCQLMNTDI LNREPVIVSLDYGLQHILPSLEPEEVSDMTFLLQTLKNSYKALVLKSAQRLQHLELQLEE RQRLTAEIDKVHSQLRKAELMARPDPNQTSTCSELVSQQAILKEMLKDIQEIEGLISSHC KESQVTAGQLSLSEQLFLIDQLRSLKNRARKTQRQIQSKLHEVEQKTAVSREFAEGIASL QQDLDDLQDGEMNLKDDELVGAKQGLKDKCKALKEKVLAFQSGLSQVMKYKEIFECVGLK WDSLQLDELQTKFSKIKNKIKEKIIHLENIVREWDKIQGLLDEIQTVTSTVRKEANILND SSSSSPAENVISAQILLQAVQQILYLTQEAANQINKNEVFDTSFKESKREEIKSLEKNVE ELKQFLQNLVSGLQSVNKEVDEVENIFHIIRHIQLELQQPLVIDINTMQDEKLRWEAIQN MMEGKFSALKCLMGKEREKQEEKSPVAAIEIETLQGCEAQLKADIAARVSALEEACRAGE LYTVALQRAARFLEECEAPAQAAAAELCASVEICQTPHWKEEEFNSAKADLENLHSKLKN LVKPEDKVCLENAVRELVDKSLAVRKKAQRKEGDEQRYFEKHKSYTETKDKVCDNLNKLE KMLRQSLSKIPMSYKEALEHLEESKVLVSCIDSAEEDLVKLRQISGEVMRLCRGSDRALG RIVTVLWENWLGLLEAAKGLEITCEELKQEWKFINEELERETIILDKLQEEQPESLKEKE KATREELVELLDFVNSFEENINQQQLLLLLLLHRIRNILNTPENAEGEAALPALCEIKAM QERCKKLYKKAQDHKDSVKAEIQERNKVTEEISAVTNALQNAASVLLQDADGKAEQLEEL QSVIGRESQALEDIMEKLRIKYSEMYTIVPAEIETQLEDCKKVLHDLEEKVSSEILQNSP QYVLKRKAETINNGLQAIEKMLQQKSENIAKAKEVQKQIWDMLDLWHYKLNELDAEVQDI VEQNSCHAQELMDILVAPLQQYQQVSQRAERRTAILNKATNKMEEYEEHLKNVKDWIEST NSLLRADAQHDSAKSLHKHTDELQMALEDSEQKQNLLHGIFMELEELSPIFETASVTQQL NEMDVQVAALQHEIAEILPQILHVADELDAIESHVKVFEKDVAEMKTILSSEDLLEFSPK DQLKHGQVILEHVGPMQKTIVHIQSYEDGLQLPGLKMQPFSVFQRARQLLRELKKLEKIT REQNELLEETVKKTEECEQEIEKLKQLLKNNLGEISHEDQPEAQKTPCPEGEMEAVKEEI IKLCQRKEDFLTRMKNSMSELHQCLQQDVPEAAAEPPASVLAQSDLIGTDVPAQQLKKRG VISLLPSLDEESEDCSLHSKGSTTTEKDASFWPSERDDERLKEDSATSWSSGTLSDGIVQ DEDVITESHSKHDEESSLQTLEAAEGPGTGDGSLAVSHQPPPAPSAALGSQTALDGGRPE PESILLLCQAQVAELEQWLAKTKMSLGSAPQSPRRQQMVEPQLADCQVRLSEIEQKVLSL LEDCGDSADYQRKTEALSLKLKEVKSNLENVQMMLQDKHNEEQVPSRERIDPEPLEILHS DGFSTSQLPLAQQPWHKGLQQPQDLKLKAAEQKSLIDFIESCVEKMQPQLEDNVSPKSES SNGESDSKSKQADATLAPKDQMGNKWQYLQQELSSKMKSPLCQLVEPQITTKMNVLPRGT FSGAGTPTVEELKTYTVQLGDLSQEANVVHAQDNVAEEVSSNLDRKLFELLLAISRCLNN MEEMLNTSVLSAEEAAVQQALYETLSVELQKLHADLSDKKDDLLKSISCAGGSTDVFCEC FNNLQARLEQTQAATASRSSSMKAGLDHNSNYLNQTRLLYDQLTEKKAALQQCLNELHGH NVSEQLQKIGDCAVELQNFESQVAKLRGHGERLQLPITLIQEAYKLEDVLDDMWGILKAK YVELNSPAISENQYEDLLRGFAELVAIGKEKVAQDPKHLTKSRAALQSHLKNHKDFFHNL MTRMAYMEAFSKRVSPSVLQKREEFWRELVNEVKLLEQKACQYGIHLESLLKDWMVFDEE CLVFNKELEALASALPSVSLVEETEERLMERIALLETIKSSVDEKHSRLYQMVKEGKKLL TAVNCPEIRSQIGKLEEQWLSLTKKVGHELHRLQTLLKLLVSYNRDSEELMKWLDSAQQR MNFWKEQSLNVSQDLATIRDNISSLFTFSKEVDEKSSLKSSVVSTASQLLHVKQADTAAL RSSLAMFEQKWGELITQLPAIQEKLHQLQMEKLSSREAIAELMAWLDHVEQQQEREEPIN SQRGAAQVKTLLQKYKEYMMEMNFKQWMVDFVNQSLLQMSTCDVESKRYERTEFAECLGE MNLRWHRLQAALNRKIQDLEHLLEDITENESKAQTLHNWLEAQSDRLRSLQTPASLISAQ NTLDDCKELENQLTEKSKTLDKLKESLASNGSAEQTPESQSLRIAELCEMKDSIVNQVAQ LKASMKSILEQWRAYDEIYAEVSLMTTRYLYCIDQCKPSEEEASLEALKKQVKTLQALQD ESENSEESWAKLQAASSNLKKNCSPSFAEIIDQKCTEAHTRWNSVNEEITDQLRAAQAAL QLWEPFDALCTETAAKFQQYSQQCAQLLDAHVPEENTIETLEQRIQEIKNLQHGLQNLAG CRTQIYLQADRIKQQAGTAAEAILMEKLQPFQRATYLEKMLQRKLDELQFNLLQLEDFNN CLETLEGRVKNCTDTFDSLCLEEGDNSELLMNQTLELAALSPSIESLNEASIKLPLSDFT LKKMQSLTRQWSQKTAAALECCSMLEGTQNDEKKFFQKCEKWMKFLEKMKEALKTDIPGR FEELQEQQRVYEMLQTEISINQQTFNSIIEKVLLSLESGEAEKRTEFISKLTLLKEQWQN VIRMVQQRKKDIDGLVSQWQLFRSSLQSLSRFLDDTNSFLAAVKSQDCYSLYQLRNVIHD FKSKAVILQRWQAMYTLVIDVGEKLRAVSDPDTSAALQEELSQLQQCWGKTQALLEKKKM QFSGTLQTCDRFEKQTKELESRLQELKEKVKDPLPVEHEELHKAKEHIKELEQSLADWAH DMKELQAMKAELAHLILTEDMMVLKEQVEHLHRQWEELCLRVSLRKQEIEDRLNAWILFN EKNKELCSWLVQMESKVLQTADVSIEDMIDKLQKDCMEEINLFSENKLHLKQMGDQLIKA SNKSRVAEIDDKLNKINDRWQHLFDVIGARVKKLKETFSFIQLLDKNMSNLRTWLARIES ELSKPVVYDICDDQEIQKRLAEQQDLQRDIEQHTAGVESVFNICDVLLHDSDACANETEC DSIQQTTRSLDRRWRNICAMSMERRMKIEETWRLWQRFLDDYSRFEDWLKASENLAARPN SSEVLYTHAKEELKKFEAFQRQIHERLTQLELINKQYRRLARENRTDSASKLKQMVHEGN QRWDNLQKRVASILRRLKHFTNRRDEFEGTRESILVWLTEMDLQLTNVEHFSKSNFDDKM RQLNGFQQEITLNTNKIDQLIVFGEQLIQKSEPLDAILIEDELEELHRYCQEVFGRVARF HQRLTSRDPGVDDEKDNSENETDQEDSREIQNDPWHKKAITEGPSSAQSLCHLMPPTQGH ERSGCETPVSVDSIPLEWDHTGDVGGSSSHEDDEEATYYSALSDVEITENPEAYLKMTTK TLKASSGKSVSEAHPWHSPGSPVCRKHRYNQAEMVGNVLSGPETSTPYKPEYVKQLSSAS SSSSKEKIPAASMSDEEPQDDQELVNIAGAEKQSGIIDRWELIQAQDLRNKLRMKQKLQQ WQQLDSDLSDISAWLDKTEQELEELQKVKLPTSMQALEQKVKKLKDLLKAFDSYKAVLLS ANLSSKEFQKADSTEFKELQNRLRKVNLHWEKATRALDNWRKGLQQALLQCQDFHDQSQK LILWLASAESRRNEAQITDPNADPNTILECQKELMQLEKELLEQQLNVNSLQDLTAYLLL KSDGDYIEEEEKVHVIGTKLKQLIEQVSHDLKTIQGNLDTKTFLLVPDDLDSGVYNPEEE KSSPAVKKMALRRTADGRNGSSTRSESHSQAVQANPRSPSFFYRVLRAALPLQLFFLLLL LLACMIPSSEEDYSCTQANNFARSFYPMLRYTNGPPPT NT seq 20997 nt NT seq  +upstreamnt  +downstreamnt atggcatcagagcagtcatctgcatcaacagaggagcaggcttcctctgaaatagatgat ctccatctaacgctgcaagtccagcgagagtttacacagaagaaaaccttcactagttgg ataaattcaatattggcaaagcatacccctccttatgttgtctcagacctgtacacagac atccagcaaggacatttgcttctggatctgttggaagtgctttcaggtcaacatctgcca cgggaaaaaggatttaataccttccaatgtagaagtaatatagaaaatgctttgacattt ttaaagagcagatcactgaagctcataaatattcatgtagctgacattattgaaggaaaa ccttccattgtgcttggcctaatctggaccattatatttcattttcatattgaagaactg gccaggacacttgcctgtacctacaatcagccttcacctgattatccaagtgctgttgac tcctctccaaaggcaaacagatcagctaaaaaaagtgctaaaattaaggagcggtggaag atgtctgctacaaaggctcttttgttgtgggcaaaagaacagtgttctctacatggctct gtcagtgtcactgatttcaagtccagctggagaagtggactggcttttttagccatcatc caaaccttgaggccaggtctggttgatctggagaaggcaaaagccagaagcaataaagaa aacctgagagaggctttcagaattgcagaactggagctgaatatcccacggcttctggag cctgaagatgttgacactgtgaatccagatgaaaaatcaatcatgacttacgtggctcag tttttgcaatactccaagaatttgcctgagtctgaagaagacatgcaggagaaagtaaga gaggccgtgggctggttggctgaacaggagaagaagttagcaaagctgctggtggaaaca gaggatgaaacatactgccagaagtacaaagaaatgatgtcatttatggaaacatttaac caagagaagatcccctttctgcctgtgttgtcatcaaaaaggggtgaagctgagctgagt ggaggccagcagcagatgagggaggagtgggataaagtgatctctcagatgaatgagtgg aaagtgaagctggaccagatgttgccctcccctctgggcagcattgaggcttggctccag gaggtggaacgtcttcaggcagaagatttgcctgatttgcaagacccgttcaaagcaatg tctgtcttcagagaaataattgtaatatttaagggcttgatggagtgttttgattctcac ttggacacccttcagtcatttaagaatgaagatgagaagaatatgccactagtcttgcct gaaaaattagaggaaatgaaaagaagatttggcaatattcgttctacaaaccccagcact tttcttgaatatcactatggactgtgctcagccattgccaatgaggtgaagttaaagctg aatatctgggacgtgaaatatggggcaaaagagtctgtggaatcactgctggaaaattgg aataacttcattgaagaaaagaaacttgaaacacaactagacattgctactcacatctgt gaagacttgaaaaacataagtggtcctggcttggctggagatcctcaagaaatcagcaag cttttgaagacagtggagtcaaagatttctacatgtaaagagtatatttccaatgtaaac accaccctacagaaagtcctgtcctcctggaggaattacacagaaaacatccacttgcta aaaacgtggctggaagaaaacagaaatgaggatccgaaagagatccctgctgagatcctg gcaaagaggaatttgattcatggttccttaaatgaagctggaaaccatctcattgaagtc agcaaagagcaagttggatcaaatattgccaaagagctgaagaaactgaacaggagatgg gcaaagttcatgaagaggacacactttcttggagaggagagcacaaatgctgctgagaag accacagagtttccaggaagcctggagaaagttgaagagctccttggaggggtggacagc tgggcagcagagatgggacgtgtgcttagcaagatcagtcacgaggagcctgtggaacct gagatggaggaacatttgcagagttgggctgcaagaggatcctcgtgcctagaccaagtt gtggcagcagaaaagatattgcactccctgaggcagaatgtttcaagtcaggtgtttcag cagcattctcacaccactgagctggaggcacgaattaaagaagccagagacaaagtagag gctgtcatgggtgacctgaacaacatcttgtccaaatctgagaaaagaccctcagagaag gaggctttgctcaattttgaagaatcgcagaaagaacttgaggcctccatttcgaaggct gtgcaacttgtcagtcaaaaattaagtcctgaaggatgtatttcaagatatgaggaagct tttaatgctctggacaataaagttcttgacaagtttttgaaagcagctgaactgctgaaa aatatttcatctgatcatgagaagttggtggtggaagatgatgttcgtaggagatgggag gcagctcgtcaggaaatcgtatcctatgtccagctcatagtagaaagggaaaaaaagaaa tttaatgcaactttaaaaaagattaataagcagttaggcaaagagaagaaactcctaagt atggataaaaccaaagggctcatcaaggagcatgaggcctttttttcacatgagggcagc atgaaggaacttaacaagtctttggaagaccttaaaacattggcaagactctcagaagaa actgtcccagggatacagacactcactgcagactgtgaaaaaaggctggagaaggttcag caaatggtggcagacacttacacagcactgctggctcgtcttgggaaaggacagtcccct cagaaagggagctccattatggcttctgagaatggagaagagtctggttcttctcaagaa gtggacagccttatggtacaggagacctcaagacctgctgcagatgcagttttggagcca gatgtgaatcatcacaatggagaaagctgtgcagacaagttggaggaagatggtgattca gcagtaccagctttgttagagagctttaacacacaaagaagtaacctggaggaacttcta cgactctgcagagataaagtagcatctgactttactgatgaaataaaaggcacttcatgc cttaactttaaggtgactgaactagaggcaatgctagaccttgaaatcagttctggttgg aaacagttggaaaacatctcatctaccttagaaaatcttgtgtctgaagtgcaacaggct gctctctctgaggcaagaaacaagctacaaagcgagtggaaagaaattcaggatattata agtatcagagtgaactctttaagggctgctatggaaattgtttgtgaaacagaaagcaaa tccatctttgtctgtcgattagtagatgaatggctgaagaaaaagtacatccaccagttt agtctgatggacaatgaccttcctgacagtgaactgaagatgctgcagagatccatatta aaacagattgaagagtgcaaacaattggaacacctcgacagttcagcaggggatgaagtt aatccactagacctgcaagctgcaagaaaagttctgattaactgtcaaaaccagcttgaa gaaatgggccataaaatgcagatgcgtgaggcagtccttaaagatctggaagcttttatg gcctccctgaggaagatccagtcttccatcagttgtctcccaaatcccccagatcaacct gaaatgcagggaaaagctttgagggaggctgcacaagaagtttctcatatggcagaagag gctaaatgtttggatgaacacctgaagggtgttaatgtctgtttggaggatgctgactct gggagaaagacttggtgtgaacaacttgttcagactttatctaaaaagctaaatgccatt tatgataccccaagtgagcaggtgcctacagaagaaaaagatttatacaggactttttcc aaaaaaagcagtgaactccttaaaaatgttcaggatctacgtgacagaattaacaaacta ggcttgaaggatccaacaattccagctattcaaaaaaggataaaatcattaacagaattg gaaaaggaattggatcgtgctgctgctgaaatgaaatctatgcatgaaattgctaataag ctcccacagatcaatgaggagaaagcagaggaagcaaatgagcagtgcagagttacagag aggttatgggaggatacaaagctcttgcttgctgaatgccaggagcagtgtgcaagggct ctggagctcctgaagcagtatcaaagctgcaaaacgagtctgaccagcatcatccagaaa caggaggttgtgctttcccagcaaacttcttacatggggaaggagaatttgaacagacta atagcaaagattgaagaagcaaaagaggaatttaatgatcactctgaagatgtagacaga ataaatcagatctgcaaaaacctgcaattccagctgaataaaatgagaagctttgaggag cctccgttcgagaatgaggctaacattattgtggacagatggctggatatcaatgaaaag accgaaaactactgtgataatttgggaagagctcaggctttgtgggacaaactcctgaac ttatctggcacaattgaagcttgggcaaacgcagagctcaagaatgcagaagatcattgc ctgactgaggaggacctcactcagctgaaggcatgcttacgggtccaagagcagaaactc caaaaattcgacagcacggtggctgagatagaagaacttctgaatagtaatgaacctcca ttggagctacaggtcatcagatcatctgttgtgcagaaaatggagctaataaaagagctc ttgtcagccaagcgagggaccagtgaactcactgtgaatgcagcagagctgaaaggagac cttgatctggccaagacacagattggaatgactgaatcacttctcaaagctttatctcct tcagacaccttagagatctttactaaactagaggagatacaccagaaaattctgcaacaa gagcaccttgtggcattactccaggaagagacagattgtcctgatgtggatgaattaaat aagcagcttaaatgtgtcactgatttattcaatagcaagaaacatgttcttcaagatcac tttatgggtgttttggatcgtcagtgcaagaattttaatgactggttcagcagcactcag ctgtctctgaaggactgctttgagccctcagaaacaaaatccatactggaagaaagacta cagaggctaaagcgcttcctgacatctgaaggcagagatagagacacccaagaggtcaaa gctttactgaataaagtgaagccttacttgcccaaagcaagcattaagcacctcagcagt cgtgtgagagatcaggaggcagagctgcagaggttgatctccaaatgccagaaacgggaa aaggagcttggtgcctctctccagcagctcagtagccttgaagaaagcagcatggccttg gaagaatggctctctgctcaggagggaaaagtaaaagggatcaataaagatgatacagaa cttgaagatgtctataaaacactattaatgcagaggaaaccgtttgactccctggctcag ctatcaaattccttgggggaggctgggctgacagaatatgaaaccctttcagaagccagt aaccttattagcaggtaccatgcactgataacacgtgtcagtgaaatggcagggaatact gagagacttccagtggaaggacaacattttgaagaccttgcccaggatgtttcttgctgg atcaaaaagcttgaggaggctcttaatcaaatgaggtcacaaggaagtgagttgccatca gacgaaaggattaatcagataaaggcaatcacaagtctcagagatgatggtgaggccaaa ataaagagcatgctggctctaggagacgctgtattgagaaatgagaaaaataagaagcca gaggttcagcaggctatttctgagctccagaaaaagtgggaaagcgtctgtcagctggcc actgaatacagcagccctgaagagcagcttcagtgcaacagggagcaatatgagcaaagc aaggaagatctgaaacaggctctaatggaactggagaaacaacaacaggagatttttgcc cttcagcctggtttggaggagaagcaagctcagctggcaaactatgctgacctcctgcag aaaacagaagccttgacttcccagtttagcaaattgaagagccagaaagagcatctccaa ggccacactgtggatccctgcttcacagaggcagaatggtcagaattaaagcaccaacat gaaaatctgctcggccagctccagaccatgatgcagacattggaaagccctgttcaagaa caccagcaggttcaggatataacaacaggcctgagcactgagctgaaaactctctctgag aagcttgctgagtgtgatggtccagcaatggaagagccatcagctgagcaaaatcagttg aaatcacaggaacaacagggacctcttagccgatgtgaagacgcggtaaagaaaagtttg gttttagcagaaactgttaaacaaaacacctcttcaccagaacaggagtttattaaggat gagatggaaacacttcagagtgagcacaaagaaagactggaagaaagacttgaaaatgtc aagcaaaagaaggagaacattttcagtgaagcccttgagttaaaagatgagtttggtaat gcaatccaaaaggaagataaggcagatgcaatgctgaagagagagacacagatcacttct gatactccaatctctgcagaggagacccccacagcagtggagctgaaggagcctttggaa atgagtgatggtcaagatgtaaatggaaatatgtctgaggaggagaggcagaatgctcca gttttggaggaaagcagtgtaccgtcagacagcccattacaggatatccatcacagcagg gacagattggggaaggctgttcagggagagactgataaggagagcccagatatggacaga cctgacaggttccaagaggatgttctggacagtgcagttctgggtggtgaagcagatctg gaaagacatcaggatggtgttgttattgaaggtgatgaatctagggaaaaaacccatcca gcacaggaggaacctagtgatgttgagaatcagtcatatagagaagatggggggcaggtt cagcagaagctgtgccagaaaggtcaaatcctggaatctgcagcagctgatgagaaagat ggtctgggatcgaatcccccagttcctgcacatgaggacacaggtgcagaagtggttgtc cagaaggagctatttcccagagtgcaagtaaacaatgaatattttgaagaggaacaaaag gtcaatgagctgaaaaatgaagtggctgaactggatatggtgcttataaatgagcaacta aaagagctggagaatttaaaaactgagctggaaacctggaaagcaaagtctgtgtgccat ggtgaagaaacaattcccaatggaacaggatcaaacggagcagagctgcaaaccacggag ccctgctgggacaggctgctccaggaactggaagctgttaaggcagtgaaacaacaacag tgctgtttaattaatgaataccagaaaaatctttctgctgcacagtcctccatgaaaaat ttgtcaacagaaaaagataacataaaaatgggtcctatgaacaacacagttcttctagag aaaattaaggcatgcatagagtccttacggaaagaaagagatgtcttaaaccagttgcaa agtcagcaagaagttttgtctcagcatttgacatgcatggataaagtgttgacagagagc caaatgaggcagctggagcactggtggcagcacatggaacaagcagtgcaaaagaaacat gatcaggttgtggcagaaattgatgaatttaacctgcttatgaataaagcacgggatatt cagaggctgatacaagaacagtatttgcaagcagagttacattcctcagctgcaggaaaa gccaaagaccctctcatttggaccacagagctacaggacattaaacatggtctttctcta ttaaaaagaaagattgagctgcagatgaaaagaatttggagtgatcaagagaaggttgct ttggagaactccatacaggatttgcagggcaaattggaagagttatcagcacagcaaact tctcaagaggatattcagaccactggtcctgctctcatgaaacatgaaatgatgaagagg ctgaaagaaaatatttcctgggtcaaagactcactgtcccaccttgatcagaaagcagca cttttccccagtgatgtcaaatcacagatcagaaattgtcagcttatgaacacggacatc ctgaacagagagcctgtgattgtatccctggattatgggctccagcacatccttcccagc ttggagccagaggaggtctctgatatgaccttccttttacaaacattgaagaattcatac aaggctcttgttttaaaatctgctcaaagattgcagcacttggagctgcagctggaggag aggcaaagactcactgcagaaatagacaaagttcactctcagctccgcaaagctgagctg atggccaggcctgacccaaaccaaaccagcacatgctcagagctggtgagccaacaagcc attctaaaggagatgctaaaggacatacaggaaatagaagggcttatctcatcccactgt aaagagagtcaggtcacagctgggcagctgagcctgtctgaacaactcttcttgattgat cagttaagaagtctgaagaatagagcaaggaagacacagaggcaaattcaaagtaaactt catgaagtagaacaaaagacagctgtctccagagagtttgctgaaggaatagcttcattg cagcaggatcttgatgacctgcaggatggtgaaatgaacctgaaagatgatgaattagta ggtgccaagcagggactgaaggacaaatgcaaagcactgaaagaaaaagtgttagctttt cagtcaggtttgtcacaagtaatgaagtacaaggaaatatttgaatgtgtaggtctgaaa tgggactcactgcagctggatgaactgcaaactaaattttctaaaattaaaaataaaatt aaagagaaaataatacacttggaaaatattgttagggaatgggataagattcaaggattg ctagatgaaatccagactgtgacatccactgtaagaaaagaagctaatatcctaaatgat agctccagctcttctcctgctgagaatgtcatatctgcacagattctattgcaggcagtt caacaaatcttgtacttaacccaggaggcagcaaatcaaataaacaaaaatgaggtattt gatacatcattcaaagaatctaagagggaagaaataaagagcctggagaaaaacgttgaa gaattaaagcagtttcttcaaaacttggtctctgggctacagagtgtaaacaaggaagta gatgaagtagaaaatatattccacatcataaggcatattcaattagaactccagcagcca cttgtgatagacataaatacaatgcaggatgaaaagctgcgatgggaagcaattcagaat atgatggaaggaaagttttctgctcttaaatgtctaatgggaaaagagagggaaaaacaa gaagagaagtctcctgttgctgctatagaaatagagacactgcaaggctgtgaagcccaa ctgaaggcagacattgctgcccgtgttagtgctctggaggaggcttgtagggctggtgag ctttataccgtggcccttcagagggctgccaggttcctggaggagtgtgaagctccagcc caggctgctgcagcagagctctgtgcatcagtggagatctgtcagactccacactggaaa gaggaagagttcaactctgcaaaggctgacttagagaacctgcactccaagctgaaaaac ctagtgaagccagaggacaaagtatgtctggaaaatgctgtaagagaactggtggacaag agtttggcagtgaggaagaaggctcaaagaaaggaaggtgatgagcagaggtattttgaa aaacacaaaagctacacagaaaccaaagataaagtgtgtgataatcttaataaactggaa aagatgcttagacagtctttgtctaagattccaatgtcttacaaagaagctttggagcat ttggaagaaagcaaggttttagtctcctgcattgactctgctgaagaggatctggtgaag ctgaggcagatctctggagaggtgatgaggttgtgcagaggaagtgacagggccctgggc aggattgttacagtgctgtgggaaaactggctgggtttgcttgaggcagccaaagggctg gaaattacctgtgaagagctaaagcaggaatggaaattcatcaatgaagagctggaacga gaaacaataattctcgataagctccaggaagaacagccagaaagccttaaagagaaagaa aaggccaccagagaggagctggtggagttgctcgattttgtgaactcatttgaagaaaac atcaaccagcagcagctccttttactcttgcttcttcaccggataagaaacatcctgaat acacctgaaaatgctgagggggaagctgccctccctgccttgtgtgagataaaggcaatg caggagcgctgtaaaaagttgtacaaaaaagctcaagaccataaagattctgtgaaagct gagattcaagagaggaacaaggtcactgaagaaataagtgctgtgacaaatgcattgcag aatgctgcatctgtgttactgcaggatgctgatggaaaggcagagcagctggaggagctt cagagtgtgattggcagagagagtcaagctctggaggatatcatggagaaacttcggatc aagtattctgaaatgtacacaatagtccctgcagagatcgaaacacagctggaggactgc aagaaagtattgcacgacctagaagagaaggttagctctgaaatcttgcagaactctcct cagtatgtgctgaaaagaaaagcagaaactattaacaatggccttcaagctattgaaaag atgttacaacagaagagtgaaaacattgcgaaagccaaagaagttcagaagcaaatttgg gatatgctggacctttggcattacaagctcaatgagctggatgcagaagtgcaggatata gtggagcagaactcctgccatgcacaggagctgatggatatcctggtggcccccctgcag cagtaccagcaggtctcacagcgtgctgagcgcagaactgccattctcaacaaggctacc aacaagatggaagagtatgaggagcacttgaagaatgtgaaagattggatagaaagcacc aacagtttgctaagagctgatgctcagcacgactctgcaaaaagcttacacaagcatact gatgagctccagatggctttggaagactcagagcaaaagcaaaatcttctgcacggtatc ttcatggagctggaggagctgtcacccatctttgaaactgccagtgtaacacaacagctg aatgaaatggatgttcaagtagcagctttacagcatgagattgcagagattcttccacaa atcctgcatgtggctgatgagctggatgccattgaatctcatgtgaaagtgtttgagaaa gatgttgcagaaatgaagacaatcctgtcatcagaagatctgttagaattttctcctaaa gaccaacttaaacatggacaggttatacttgagcatgttggtcccatgcagaaaactatt gttcatatacagtcctatgaagatggtcttcagctgccagggctaaaaatgcaacctttc tcagtcttccaaagagcaagacaactcttgagagaattgaagaaattagaaaaaattact agggaacaaaatgagctactggaggaaactgtaaagaaaacagaagaatgtgagcaagaa attgaaaagttgaaacaactcctaaagaacaatttgggtgaaatatcccatgaagatcaa ccagaggctcagaagactccctgtccagagggagaaatggaagctgtaaaagaagaaatc ataaaactgtgccaaagaaaggaagatttccttaccaggatgaagaattccatgtctgag cttcaccagtgcctacagcaagatgtgcctgaagcagcagctgaacctccagcctctgtg ttagcacagagtgacctgattgggactgatgttcctgctcagcagttgaaaaaaagagga gtgatatctcttctgccttccttagatgaagaatcagaagactgttctttacacagcaag ggaagtacaaccacagagaaagatgcaagcttttggccttcagaaagagatgatgaaagg ctcaaggaagacagtgcaacctcctggtcctctggtaccttgtcagatggcattgttcag gatgaggatgttataactgaatcacacagtaaacatgatgaagaatcatctctgcaaact ttggaggctgctgaaggtcctggcacaggcgatggcagtctggctgtgagccaccagccg cctccagcgcccagcgccgccctgggctcgcagacagcgctggatggagggaggcctgag ccagaatccatcctcctgctgtgccaggcccaggtggcagagctggaacaatggctggcc aaaactaaaatgtccctgggctcagcccctcagagcccccgaaggcagcagatggtggag ccgcagcttgctgattgccaggtgaggttatcagagattgaacaaaaggtcctttcctta ctggaagattgtggagatagtgcagactaccaacgaaagacagaggctctttccttgaag ttgaaggaggtgaagagcaatttggaaaatgtccagatgatgcttcaagacaagcacaat gaagagcaggttcccagcagggagaggattgacccagagcccctggagatcctgcactct gatggtttcagcacatcccagctgccccttgcccaacagccttggcacaaggggcttcag cagccacaggacctgaaattaaaagcagctgagcagaaaagcctcattgactttattgag tcatgtgtggaaaaaatgcagccacagcttgaggacaacgtgagtccaaaatcagaatcc agcaatggagagtctgactcaaagagcaagcaggctgatgccaccttagctccaaaggat caaatgggtaataaatggcagtatttacagcaggaactctcatcaaagatgaaatctcct ctctgccagcttgtggaacctcagatcacaacgaagatgaatgtgctgcctcgaggcaca ttctcaggtgcaggaacccctactgtggaagagctgaaaacttacactgtccagttggga gacctaagccaggaggcaaatgtagtgcatgcacaggataatgtggcagaggaagtctct tccaatttggacagaaagttgtttgagctgcttctggcaatcagccggtgtttgaataac atggaggagatgctgaacacctctgtgctctccgctgaagaggcagctgtgcagcaggct ctctatgagactctgtctgtggagctgcaaaaacttcatgctgatctgagtgataaaaag gatgatcttctgaagtccatcagctgtgctggtgggagcacagatgtgttctgcgagtgc tttaacaacttgcaggcacggctggagcaaactcaagctgccactgcttcaaggagcagc tccatgaaagctgggctggatcataatagcaattacctgaatcaaaccaggctactctat gatcagttaactgagaaaaaagctgctctgcaacaatgcttgaatgaactacatggacat aatgtttctgaacagcttcagaaaattggtgactgtgctgtggagctgcaaaactttgaa agccaagtagcaaaattgagaggccatggagaaagattgcagttacctatcaccttaatc caggaagcttataaattagaggacgttctggatgacatgtgggggattctgaaagcaaag tatgtggagctgaactcccctgccatcagtgaaaaccagtatgaggatttgcttcgtggg tttgcagagctggtagctattggaaaagagaaggtggcacaagatccaaagcacctaaca aaaagcagagcagctctgcagtctcacctgaaaaatcacaaggattttttccacaacctc atgacacgtatggcttacatggaagcgttttccaagagagtgagtccttctgtcctgcaa aagagagaggaattctggagagagctggtgaatgaagtcaaattgctggagcagaaggcc tgccagtatggtatacacttagagagcctgctaaaggattggatggtatttgatgaggaa tgcctagttttcaataaggagttagaagcattagcctctgcgttgccttctgtcagtttg gttgaagaaactgaagaaagattaatggaaaggattgcacttctagagacaatcaaaagc agtgttgatgaaaagcattccaggctgtaccagatggtgaaagaagggaagaagttgctg actgctgtgaactgtccagaaataagaagccagattgggaagctggaagagcagtggttg tctttaaccaaaaaagttggccatgagctacaccgacttcaaacattactgaaactcctg gtcagctacaacagagactcagaggaattgatgaaatggttggattctgctcagcagaga atgaatttctggaaggagcagtctctcaatgtgtcacaagatcttgccaccatcagggac aacatcagcagtttgtttacattttctaaggaagttgatgaaaaatcttccctgaagtca tcagtggtgagcactgccagccagctcctccacgtgaagcaagctgatactgcagcactt aggtcatccttggcaatgtttgagcaaaaatggggagaactgattacacagctcccagcc atccaagaaaagcttcaccagcttcagatggaaaagctttcatcacgggaagctattgct gaactaatggcctggctggaccatgtggaacagcagcaggagcgtgaggagccaataaat tcacaacgtggtgctgcccaggtcaagaccctccttcagaagtacaaggaatacatgatg gaaatgaactttaagcagtggatggtagattttgttaaccagtccctgctgcagatgagc acctgtgacgtggagagcaagcgctacgaaaggacagagtttgctgagtgcctgggtgag atgaacctgcggtggcaccggctgcaggcagccctcaacagaaagatacaagacctggag caccttttggaggatattactgagaatgagagcaaagcccagactctgcacaactggctg gaagctcagagcgatcgactgagatccttacagaccccagcaagtctgatctctgcacag aacaccttagatgattgcaaggagctagaaaatcaactcacagaaaaatccaaaactctt 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tctccaagcatagaaagtttgaatgaagcaagcataaagctgccactcagtgacttcacc ctgaagaaaatgcagagcctgactcgtcagtggagtcagaaaacagcagctgctctggaa tgttgcagtatgcttgaggggacccaaaatgatgagaagaaattctttcagaaatgtgaa aagtggatgaaattcctagaaaaaatgaaagaagctttaaaaacagatattccaggacgg tttgaagaactgcaagaacaacagagagtatatgagatgttgcagactgagatttccata aatcagcagacatttaattctatcatagaaaaagttctactctccttggaatctggagaa gcagaaaaaaggacagagtttatttccaagctcacactgctgaaagagcagtggcagaat gttatccggatggttcagcagaggaagaaagatatcgatggactcgtgagccagtggcag ctcttcaggagttccctgcagagcctcagcagattccttgatgacacaaacagcttcctc gcagctgtgaagagccaggattgttacagtctttaccagcttagaaatgtcattcatgat ttcaagagtaaggcagtgatccttcagaggtggcaggccatgtacaccttggtcatcgat gtcggggagaagttgcgcgctgtctccgatcccgacaccagtgctgctctccaggaggag ctcagccagttacagcagtgctgggggaaaacccaggccctgctggagaagaagaagatg cagttcagtggcaccctgcagacttgcgaccgctttgaaaagcaaaccaaggaactggaa agcagactgcaagagctaaaggagaaagtaaaagatccactccctgttgaacatgaagag ctccacaaagccaaggaacatattaaggagctggagcagtcgctggcagactgggcccac gacatgaaggagctgcaggccatgaaggcggagctggcacacctcatcctcaccgaggac atgatggtgctcaaggagcaagtggagcatttgcacaggcagtgggaagagctgtgcttg cgggtgtctctgcggaagcaggagatcgaggataggctcaatgcctggatcttgttcaat gagaagaataaggagctgtgctcctggctggtccaaatggaaagcaaagtgttgcagact gcagatgttagcattgaagacatgatagacaaattgcagaaggactgtatggaagaaata aacctgttcagtgaaaataagcttcatttgaaacaaatgggtgatcagctaatcaaggct agcaacaagagccgagttgcagaaatagatgataaactcaacaaaatcaatgatcgctgg cagcacctctttgatgtcattggagcacgggtgaagaaactgaaggaaacattttctttt atacaactattggacaaaaacatgagtaaccttcgcacctggctggcccggattgagtct gagctttccaagcctgttgtttatgacatctgtgatgaccaagaaatccagaagagactg gcagaacagcaggacctgcagagagacatagagcagcacacagcaggcgtggagtccgtg tttaacatctgtgacgtcctgctacacgactcagatgcgtgtgctaatgagacagagtgt gactccatccagcaaaccaccaggagcttggacagacggtggagaaatatctgtgccatg tccatggaaaggcgaatgaaaatcgaggaaacctggcgtctgtggcagaggtttttggat gactattctcgctttgaagattggctaaaagcatctgaaaatttagcagctaggcccaat tcttcagaggtcttgtacacacatgcaaaagaggagctgaagaaatttgaggcgttccag cggcagatccacgagcgcctgacgcagctggagctgatcaataagcagtaccggcgcctg gcccgagagaaccgcactgactcggccagcaagctcaagcagatggtgcatgagggcaac cagcgctgggataacctccagaaacgagtagcttccattctcaggaggctcaagcacttc accaatcggagagatgagtttgaggggacgagggaaagcatccttgtgtggctcacagaa atggacttacagctgacaaacgtggaacacttctcaaaaagtaactttgacgataaaatg cgccagttaaatggtttccaacaggaaataacgttaaacaccaataagattgatcaacta attgtttttggggagcagttgattcagaagagtgagcctttggatgccatcctgattgaa gatgaattggaagagcttcatcgatactgtcaggaggtgtttgggcgagttgcccggttc catcaaagactgacttcaagggatcctggagtggacgatgaaaaagataactctgaaaat gagacggatcaagaagactccagagaaatccagaatgatccctggcataagaaagccatc actgaggggccctcatcagcacagtccctttgccaccttatgcccccaactcagggccat gagagatcaggctgtgagacccctgtcagcgttgactccatcccacttgagtgggatcac acaggtgatgtgggaggttcttcctctcatgaagatgatgaagaagcaacatattacagt gctctgtcagatgtagaaatcactgaaaaccctgaggcatatcttaaaatgaccacaaaa actttgaaagcatcttctggaaagtctgtttcagaagctcatccttggcattctccaggt agcccagtctgcaggaaacacagatataatcaggcagagatggttggaaatgtgttgtct 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