Thermobifida halotolerans: NI17_002945
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Entry
NI17_002945 CDS
T08032
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thao
Thermobifida halotolerans
Pathway
thao00300
Lysine biosynthesis
thao00550
Peptidoglycan biosynthesis
thao01100
Metabolic pathways
thao01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thao00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NI17_002945
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NI17_002945
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NI17_002945
Enzymes [BR:
thao01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NI17_002945
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Paralog
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UOE20220
UniProt:
A0A399G7K6
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All DBs
Position
655874..657283
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AA seq
469 aa
AA seq
DB search
MIALTLDRIAEITRSRIRGSAQPTDIVNGPVVIDSRQAVPGSLFVALGGERVDGHDFADA
AVSAGATAVLGSRPVDAPQLLVDGGDDEVVAALARLARAVVDELPDADVIGVTGSSGKTT
TKDLLAQVLSRIGPTIAPPGSFNNELGHPLTVLRADETTRFIALEVAARGLGHIAHLCRV
APPRIGVVLNVGSAHMGEFGDRATIARAKGELVEALPDADRGGVAVLNADDDAVIGMAAR
TSARVVSYGLADTADVRAEQVDLDDTGRARFTLAIGGATARVQLRLIGIHQVHNALAVAA
VLHELGTGVADIATALGEAGSVSRWRMEVTERADGVTVVNDAYNANPESMGAALRTLATL
ASERRAFAVLGHMAELGPSHRAEHERIGRLVTESGVDVLVVVGEQAAGIADGAAAVADWP
GETLRVADVAEAVAVLRERLRPKDIVMLKGSRVAGLEKVAEQLTVEAAE
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
ttgatcgcgctgacgctcgatcggatcgccgagatcacccgatcccgaatacgcggatcg
gcgcagcccacggacatcgtcaacggtccggtggtcatcgactcacgccaggcggtcccc
ggttcgctgttcgtcgccctcggcggcgaacgggtcgacggccacgacttcgccgacgcc
gcggtcagtgccggggcgacggccgtgctgggctcccggccggtggacgcgccccagctg
ctggtcgacggcggcgacgacgaggtcgtggcggccctggcgcggctggcccgcgcggtc
gtggacgaactgcccgacgccgacgtcatcggggtcaccggctcgtccgggaagaccacc
accaaggacctgctggcccaggtgctgtcccggatcggccccacgatcgccccgcccgga
tcgttcaacaacgaactcggccatccgctgaccgtcctgcgcgcggacgagaccacccgc
ttcatcgcgctggaggtcgccgcccgcggtctgggacacatcgcgcacctgtgccgggtg
gcgccgccgcgcatcggcgtcgtgctcaacgtcggcagcgcccacatgggcgagttcggc
gaccgcgcgaccatcgcccgggccaagggcgaactcgtcgaggcgctgcccgacgccgac
cggggcggcgtggcggtcctcaacgccgacgacgacgcggtgatcggcatggccgcgcgc
acctcggcccgggtggtcagctacggcctggccgacaccgccgacgtgcgggccgagcag
gtcgacctggacgacacgggacgtgcccgcttcaccctcgccatcggcggcgccacggcc
cgggtgcaactgcggctgatcggtatccaccaggtgcacaacgccctggccgtcgccgcg
gtgctgcacgaactgggaacgggcgtcgccgacatcgccacggccctgggcgaggcgggc
tccgtgagccgctggcgcatggaggtcaccgaacgggcggacggggtgaccgtcgtcaac
gacgcctacaacgccaaccccgaatccatgggcgcggcactgcgtacgctggccacgctg
gcctccgagcgccgcgccttcgcggtgctgggccacatggccgagctcggcccgtcccac
cgggccgagcacgagcgcatcggacgactcgtgaccgagagcggggtggacgtcctcgtt
gtcgtcggcgagcaggcggcgggcatcgcggacggagccgcggccgtcgccgactggccg
ggcgagaccctgagggtcgccgatgtcgcggaagcggtcgcggtgctcagggagcgcctg
agacccaaggacatcgtcatgttgaagggatcacgagtggccgggctggagaaggtagcc
gagcagctgaccgtggaggccgccgaatga
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