KEGG   Thalassobaculum sp. OXR-137: T8K17_06545
Entry
T8K17_06545       CDS       T09627                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
thar  Thalassobaculum sp. OXR-137
Pathway
thar00290  Valine, leucine and isoleucine biosynthesis
thar00620  Pyruvate metabolism
thar01100  Metabolic pathways
thar01110  Biosynthesis of secondary metabolites
thar01210  2-Oxocarboxylic acid metabolism
thar01230  Biosynthesis of amino acids
Module
thar_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:thar00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    T8K17_06545 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    T8K17_06545 (leuA)
Enzymes [BR:thar01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     T8K17_06545 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: WPZ35797
LinkDB
Position
complement(1378275..1379951)
AA seq 558 aa
MLNRMPIHKYRAYAQVDLPKRSWPDKVIDTAPIWCSVDLRDGNQALVDPMDGARKRRMWD
ALVKMGFKQIEVGFPSASDTDFNFVRQLIEENLIPDDVTIQVLTQAREHLVQRTFESVLG
AKNVIIHLYNSTSELQRRVVFQQDQEGVKKIATDGAEMVRDRLPMLKGQNVQLQYSPESF
TGTELDYALEVCEAVMDIWAPVVDNQIILNLPSTVEMSTPNIYADQIEWMHRNFSRRDRI
CLSVHPHNDRGTGVAAAELAVMAGADRVEGTLFGNGERTGNVDIVTLGLNLFTQGVDPKL
DFSDINGLMETAEYCNQLPIHPRHPYAGELVHTAFSGSHQDAINKGMKAIKAANSGVWEV
PYLPIDPHDIGRDYEAVIRVNSQSGKGGIAYVLENDHHIRLPKEWQAQFSQVIQRLTDAS
SQEISSQEIWNAFEKEYVTQPEGRFNLVNFESRRVPGSNQVVEVNAVLTDNGTEKTITGQ
GNGPVNAFSHMMRKEFGLKFKLKDYVEHTRSVGSDAEAAAYIELKVPDETGTSIFGVGID
TDITLAPIKAVVSACNRL
NT seq 1677 nt   +upstreamnt  +downstreamnt
atgttgaaccgcatgccgatccacaaataccgcgcctacgcccaggtcgatctgcccaag
cggtcctggccggacaaggtgatcgacaccgccccgatctggtgctcggtcgatctccgc
gacggcaaccaggctctggtcgacccgatggacggcgcccgcaagcggcggatgtgggat
gcgctggtcaagatgggcttcaagcagatcgaggtcgggttcccgtccgcctcggacacc
gacttcaatttcgtgcgccagctcatcgaggagaacctgatccccgatgacgtcaccatc
caggttctgacccaggcccgcgaacatctggtccagcgcaccttcgagagcgtgctgggc
gccaagaacgtcatcatccacctgtacaactcgacctcggagctgcagcgccgggtggtg
ttccagcaggaccaggagggcgtgaagaagatcgccaccgacggcgcggagatggtgcgc
gaccgtctgccgatgctgaagggccagaacgttcagctccagtattcgccggagagcttc
accggcaccgagctggactatgcgctggaggtctgcgaggcggtcatggatatctgggcg
ccggtggtcgacaaccagatcatcctgaacctgccctccaccgtcgagatgtcgacgccg
aacatctatgccgaccagatcgagtggatgcaccgcaacttcagccggcgcgaccggatc
tgcctgtcggtccacccgcataacgaccggggcaccggcgtggcggcggccgagctggcg
gtgatggccggcgccgaccgggtcgaaggcaccctgttcggcaacggcgagcgcaccggc
aacgtggacatcgtcaccctgggcctgaacctgttcacccagggcgtcgacccgaagctg
gacttctccgacatcaacggcctgatggagacggcggaatactgcaaccagctgccgatc
cacccgcgccatccctatgccggcgagctggtgcacaccgccttctccgggtcgcaccag
gacgcgatcaataagggcatgaaggcgatcaaggcggcgaatagcggcgtgtgggaggtt
ccctacctgccgatcgatccgcacgatatcggccgggactacgaggcggtgatccgggtg
aactcgcagtcgggcaagggcggcatcgcctatgtgctggagaacgaccaccacattcgg
cttcccaaggaatggcaggcccagttcagccaggtcatccagcggctgaccgacgccagc
agccaggagatctccagccaggagatctggaacgccttcgagaaggaatacgtcacccag
ccggagggccggttcaacctggtcaacttcgaatcccgccgggtacccggctcgaaccag
gtcgtcgaggtcaatgccgtgctcaccgacaacggcacggagaagacgatcaccggccag
ggcaacggcccggtcaacgccttctcgcacatgatgcgcaaggaattcgggctgaaattc
aagctcaaggactatgtggagcacacccgctcggtcggctccgacgccgaggccgccgcc
tatatcgagctcaaggttccggacgagaccggcaccagcatcttcggcgtgggcatcgac
accgacatcacgctcgcgccgatcaaggccgtggtgagcgcgtgtaaccgcctgtaa

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