Thermus sp. CCB_US3_UF1: TCCBUS3UF1_10470
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Entry
TCCBUS3UF1_10470 CDS
T01866
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thc
Thermus sp. CCB_US3_UF1
Pathway
thc00300
Lysine biosynthesis
thc00550
Peptidoglycan biosynthesis
thc01100
Metabolic pathways
thc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TCCBUS3UF1_10470
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TCCBUS3UF1_10470
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TCCBUS3UF1_10470
Enzymes [BR:
thc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TCCBUS3UF1_10470
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEV16092
UniProt:
G8NCS9
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Position
complement(1025398..1026645)
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AA seq
415 aa
AA seq
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MAEATGGRLHPGGKPVRDLHWDSREIGPRSLFVALPGTRVHGRAFAEEARARGAHLVLSD
RPGPATVEVADTAQALLRLGGALRGLFPGLVVAVGGSSGKTTTKEALAQGLGFPAPPGNQ
NTAPPLARFFLHLDPKAEGAVVELGVDRKGEMAELMALAQPHLGVLTALGEEHLQALGSL
EGVVAEESGLLQAPQVLVSLQAAEVLGAFGLGGGWPTYGFGQATFPGHDLSLLPEESRFR
YGGLEVRVPYPGLGPALGALAALAVADLLGRDPKEVAERLEGLRLPPGRMERREKEGVVF
LHDAYNANPLSVKAGLAWLAAQPGRKWAVLGEMRELGEEAFRLHLEVAEEAVRLGLRPLY
LGSYAPAQAALGGEAAGSLEEALAWLKARVKPGDLVYLKASRALGLERILDLWDA
NT seq
1248 nt
NT seq
+upstream
nt +downstream
nt
gtggccgaggccacggggggccggctccaccccgggggcaagcccgtgagggacctccat
tgggatagccgggaaataggcccaaggagccttttcgtggccctccccgggaccagggtc
catggccgggccttcgctgaggaagcccgggcccggggggcccacctggtcctctccgac
cggccagggccggccacggtggaggtggcggacacggcccaggcccttctgcgcctggga
ggcgccctgcgggggctattcccggggttggtggtggccgtggggggtagctcgggcaag
accaccaccaaggaggccctggcccagggcctgggctttcccgccccacccgggaaccag
aacaccgccccgcccctggcccgctttttcctgcacctggaccccaaggcggaaggagcc
gtggtggagctgggggtggaccgcaagggggagatggcggagctcatggccctggcccag
ccccacctgggggtgcttaccgccctaggggaggagcacctccaggccctgggcagcctc
gagggggtggtggcggaggaaagcggcctcctgcaagcccctcaggtcctggtgagcctg
caggcggctgaggtgctcggggccttcggcctggggggaggctggcccacctacggcttt
ggccaggccaccttccccggccacgacctctccctcctccccgaggaaagccgcttccgc
tacggcggcctggaggtgcgggtgccctacccgggcctgggcccggccttgggggccttg
gcggccctggccgtggccgacctcctggggcgggaccccaaggaggtggccgagcgcctg
gagggcctccggcttccccccgggcggatggagcggcgggaaaaggagggggtggtcttc
cttcacgacgcctacaacgccaaccccctttcggtcaaggcggggctggcctggctggcc
gcccagcctgggcgcaagtgggcggtcttgggggagatgcgggagctgggggaagaagcc
tttcggctccacctggaggtggccgaggaagcggtccggctggggctcaggcccctttac
ctgggaagctacgccccagcccaagcggccctgggcggggaggccgcaggcagcctggag
gaggccctggcgtggcttaaggcccgggtaaaacccggggatttggtctacctcaaggcc
tcgagggccctagggctggaacgcatcctggacctatgggacgcctag
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