Candidatus Tokpelaia hoelldoblerii: BHV28_13270
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Entry
BHV28_13270 CDS
T04701
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thd
Candidatus Tokpelaia hoelldoblerii
Pathway
thd00300
Lysine biosynthesis
thd00550
Peptidoglycan biosynthesis
thd01100
Metabolic pathways
thd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BHV28_13270
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BHV28_13270
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BHV28_13270
Enzymes [BR:
thd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BHV28_13270
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
NAD_binding_8
DUF630
Motif
Other DBs
NCBI-ProteinID:
AQS42010
UniProt:
A0A1U9JVY6
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All DBs
Position
complement(1417398..1418819)
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AA seq
473 aa
AA seq
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MKPLWTGQAFVDAIGGSVSGVIPESIKGISIDSRTLEKGEAFFAIRGANLDGHEFAAAAA
KAGAAVLVVEKAQADVLQKTGVALLLVDDVLAALTRLGVAARERTKAEIIAVTGSVGKTT
TKEMLRFCLGGQGRVHANPASFNNHWGVPLTLARMPEETDYGIFEIGMNHENEIRPLVKL
VRPHVALITRIAAAHMGYFTSLEAIAHAKAEIFEGLAPQGVGLLNADDPLCSYLEKRARA
AGCGTIATFGRAENADYRLLENYPHAGGSCFEVDLKGTQAVVKLGVAGSHMVDNALGVLA
AADCVGADVAHIVLALPEFREMSGRGARYTLSMPDGGCLTLIDESYNANPASMRAGLALL
GDSAPASRGRRIAVLGDMLELGQYSRAAHEDLAGPLRLAKTNLVFLAGKEMEYLERTLRD
EVPVEYRKSVADLLPAVFAALRSGDVVMVKSSNGIGTARIVSALLERYPPLVS
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgaaacccttgtggacaggacaggcttttgttgacgctatcggcggtagcgtatcaggt
gtgatacccgaaagtatcaaagggatttccattgacagccgcacgctggaaaagggtgag
gcgttttttgccattcggggggcaaaccttgacggccatgaatttgccgccgccgcggca
aaggccggtgcggcagtgctggtggtggaaaaggcgcaggcggatgttttgcagaaaacc
ggcgtcgccctgttgctggtggatgatgtcctggcagcgctcacgcggctgggggtggcc
gcgcgtgagcgcacgaaagctgaaattattgctgtcaccggttctgtcggcaagaccacc
accaaggaaatgctgcgcttctgtctgggcgggcagggcagggttcatgccaatccggcc
tcgttcaacaatcactggggcgtgccgctgacgctggcgcggatgccggaagaaaccgat
tacggcatttttgaaatcggtatgaatcatgaaaatgaaatccggccgctggtgaaactt
gtgcgcccgcatgtggcgctgatcacccgcattgccgctgcgcatatgggctattttact
tctcttgaggcgattgctcatgccaaggcggaaatttttgagggtttggcgccgcaaggt
gttggcctgctcaatgctgatgacccgctttgttcctatctggagaaacgcgcccgggcg
gcagggtgcgggacaatcgccacattcgggcgggcggaaaatgccgattaccggctgctt
gaaaattatccccatgctggcggttcgtgcttcgaggtggatttgaagggcacgcaagcc
gtggtgaaacttggcgtggcgggcagccatatggtggataatgcgctgggtgttctggcg
gcggcggattgtgtcggggcggatgtggcgcatatcgtgctggcgctgccggagtttcgc
gagatgagcggacggggggcgcgctatacgctgtccatgccggatggcgggtgtttgacg
ctgattgatgaaagctataacgccaaccccgcttcaatgcgggcagggctggcgttgctg
ggtgacagcgcgcctgcatcgcgcggacggcgcatcgccgttcttggcgatatgctcgag
cttgggcaatattcgcgcgccgcacacgaggatttggccgggccgctgcgtctggcaaag
acaaatcttgtatttctggcggggaaagagatggaataccttgaacgcaccttgcgtgat
gaggtgccggtagagtatcgcaaaagcgtggcggaccttctgccggcggtgtttgcggcg
ctgcgttcgggtgatgtggtgatggtcaaatcctcaaacggcattggcacggcacgcatt
gtgtcggccttgctggagcgctatccgccactggtttcctga
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