Thermococcus sp. 4557: GQS_05745
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Entry
GQS_05745 CDS
T01588
Name
(GenBank) phosphoribosylformylglycinamidine synthase II
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
the
Thermococcus sp. 4557
Pathway
the00230
Purine metabolism
the01100
Metabolic pathways
the01110
Biosynthesis of secondary metabolites
Module
the_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
the00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
GQS_05745
Enzymes [BR:
the01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
GQS_05745
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AEK73049
UniProt:
G0HJC0
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Position
complement(1068960..1071101)
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AA seq
713 aa
AA seq
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MFPHEEKLIRERLGREPNELEWAMLEVMWSEHASYKSSRPWLKLLPTENEHVILGPGEDA
GIVKFDDETWVVVGIESHNHPSAVEPYGGAATGVGGIVRDILCMGARPIALLDPIRFGPL
EKERNRYLFEYVVKGISDYGNRIGVPTVGGETEFDESLDSYTLVNVACVGIMRPEHLVHS
YVTEAGLKLILVGNRTGRDGIHGVTFASEELGENAEEEDRSAVQIPDPFTEKLLIEATLE
AVYTGKVKALKDLGGGGLTCAASEMAGKKGFGAVIHADRVPLREPGMTPTEVMISESQER
MLFAVDETDVDFLGAIFEKYGLEWTVVGEVIEEPRFVIYWRGEKVADLPVELLADVPTIE
WELKPYSIEKPAETPDVSFGDALDLVWSSPNVVSKRWIWQQYDHEVQGRTVLKPGADSAV
LKLSEEYGLVFVADGNPSHSYLNPYHGAMGAVAEVVRNLVSVGAEPLALVDNLNFASPER
PEVYWSFAETVRGLADAAKAFGLAYVSGNVSFYNEVVDRPIKPTPVVAGLGKVKLEEIPE
MGLSGGLLIGVVGITKAELGGSELFARLGVEGGFAPRVNLDEEKANAEGILGAVRKGLVR
AVHDVSRGGIAVALGEMAITGKTGFAVDLSKVPSETSNPVETAFSESHGRYIVTFPEENL
DELKALFKHFAVIGKAGGSDAVFYWSGKELLRRPLKEVRATHESLPKLLGEEE
NT seq
2142 nt
NT seq
+upstream
nt +downstream
nt
atgtttccgcacgaggaaaagctcatccgtgaaaggctcggcagggagccgaatgaactt
gagtgggcgatgctcgaggtcatgtggagcgagcacgcttcctacaagtcgagcagaccg
tggctcaagctcctgccgactgagaacgagcacgtgattttgggccccggcgaggacgcc
gggatagtgaagttcgacgacgaaacgtgggtagtcgttggaatcgagagccacaaccac
cccagtgcggttgagccctatgggggagcggccacgggagtcggtggaatcgtcagggac
atactctgcatgggtgcgaggccgattgccctgctcgaccccatacgcttcggcccgctg
gagaaggagagaaaccgatacctcttcgagtacgtggttaaggggatatccgactacggc
aacaggataggcgttcctaccgtgggaggcgagacggagttcgatgagagcttggacagc
tacacgctcgttaacgtcgcctgcgtcgggataatgaggccggaacatctcgtccacagc
tacgtgaccgaggcaggactcaagctcatactcgtcggcaacaggaccggcagggacggc
atccacggagtcaccttcgcgagcgaggaactcggagagaacgcggaggaggaagaccgc
tccgccgtccagatccccgaccccttcaccgagaagctgctgattgaggccacacttgag
gctgtctacacgggcaaagtaaaggccctcaaagacttgggtggcggcggtttgacctgc
gccgcatctgagatggccggaaagaagggcttcggcgcggttattcatgccgacagggtt
ccgctccgcgagccgggaatgacgccaaccgaggtcatgatttccgagagccaggagagg
atgctcttcgcggtcgacgaaaccgatgttgacttcctcggggcaatcttcgagaagtac
ggcctcgagtggacggttgtcggggaggtcatcgaggagccgcgctttgtgatatactgg
aggggcgaaaaggtcgcggaccttccggtggagctcctggcggacgttcccacgatagaa
tgggagctgaaaccttacagcatcgaaaaacctgctgagacaccggacgtttcttttgga
gatgctctcgatctcgtctggagcagtccgaacgtcgtaagcaagcgctggatttggcag
cagtacgaccacgaggttcaggggaggacggtcctcaagcccggagcggattctgccgtg
ctcaagctcagcgaggaatacggcttagttttcgtggccgacggaaaccccagccacagc
tacctcaacccctaccacggcgcgatgggggccgtcgccgaggtcgtcaggaaccttgtc
agcgttggggctgaaccattggctctggtggacaacctcaacttcgcatcgcccgagaga
ccggaggtttactggagtttcgccgagaccgttaggggattggccgatgcggccaaagcc
ttcggtttagcgtacgtcagcggcaacgtcagcttctacaacgaggtcgttgataggcca
ataaagccgacccccgtcgttgccggcctcggaaaggtaaagctcgaggaaatcccggag
atgggactgagcggcggactgctcataggtgtcgtcgggataacgaaggcggaactcggc
ggctcggagttgtttgcgagactcggcgtcgaaggcggctttgctccgcgcgtgaacctc
gacgaggagaaggccaacgccgagggaatcctgggggctgtacgaaaaggccttgtcaga
gcggttcacgacgttagcaggggtggaatagcggtagctctgggggagatggccatcact
ggaaagacgggcttcgcggttgacctttcaaaggtcccctccgaaacatcgaacccggtg
gaaacagctttcagcgagagccacgggcgctacatagttaccttccccgaggagaacctt
gacgagcttaaagcactcttcaaacacttcgcggtcatcggaaaggcggggggaagtgat
gcggtcttctactggagcggaaaggaactcctgagaagacctctcaaagaggttagagca
acccacgagtccctgccaaagctcttgggtgaggaggaatga
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