KEGG   Thermomonas sp. HDW16: G7079_03340
Entry
G7079_03340       CDS       T06498                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
theh  Thermomonas sp. HDW16
Pathway
theh00290  Valine, leucine and isoleucine biosynthesis
theh00620  Pyruvate metabolism
theh01100  Metabolic pathways
theh01110  Biosynthesis of secondary metabolites
theh01210  2-Oxocarboxylic acid metabolism
theh01230  Biosynthesis of amino acids
Module
theh_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:theh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    G7079_03340
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    G7079_03340
Enzymes [BR:theh01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     G7079_03340
SSDB
Motif
Pfam: HMGL-like HCS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: QIL19842
UniProt: A0A6G7ZSZ7
LinkDB
Position
complement(754508..756052)
AA seq 514 aa
MTHANTTDRIRIFDTSLRDGEQSPGFTMSASQKIAFAHALADLGVDVIEAGFPNSSPADF
GAVQAIAREVRGASIATLARCHPGDIEACARALDDAAAPRIHVFISTSPLHRQHKLNMSR
EQVIEHAAMGVQLARKHVDDVEFSAEDAFRTEREFLVEVFDAAVAAGARTLNVPDTVGYA
TPEEIRELFRYLRANVKGADGVTFSAHCHNDLGLAVANSLAAIEGGARQVECTINGIGER
AGNAALEELVMAMKVRGGWYGADTCIDTRKLLETSRLLSRITGIQVQRNKAIVGLNAFAH
ESGIHQHGMLKNRDTYEIMRPQDVGWPDSQLVLGRHSGRAAVADRLRQLGYVLEDEQLDQ
VIAGAKALTQTQHVIGDADLQRLVEGERYGPGWRISALSLTDYGQHTRAHVDLSDPDGKH
LLQSAEGEGPIAAVFAALAQATGVDFELESYEVHSMGIGRDARGEANLSGRIDGETLSGQ
GTSRDVLEASAIAWLDVANRVLRARQAQPRVEAA
NT seq 1545 nt   +upstreamnt  +downstreamnt
atgacccacgcaaacacgaccgatcgcattcgcattttcgacaccagcctgcgcgacggt
gaacaatcgcccggtttcaccatgagcgcgtcgcagaagatcgccttcgcccatgcgctg
gccgatctcggcgtcgatgtgatcgaagccggctttcccaacagctcccccgccgatttc
ggcgcggtgcaggccatcgcccgcgaggtgcgcggagcgtccatcgccaccctcgcccgc
tgccatccgggcgacatcgaagcctgcgcacgcgcattggacgatgccgccgcgccgcgc
atccatgttttcatctccaccagcccgctgcaccgccagcacaagctcaacatgagccgt
gaacaggtgatcgagcacgcggcgatgggcgtgcaactggcacgcaagcacgtggacgat
gtggagttctccgcggaggacgccttccgcaccgagcgcgagttcctggtcgaagtgttc
gatgccgcggtggccgctggtgcgcgcaccctgaacgtaccggacaccgtgggctatgcc
acgccggaggaaatccgcgaactgttccgctacctgcgcgccaacgtgaaaggcgcggac
ggcgtgaccttcagcgcgcactgccacaacgacctgggcctggcggtggccaattcgctc
gccgcgatcgaaggcggcgcgcgccaggtcgaatgcaccatcaacggcatcggcgaacgc
gccggcaatgccgcgctggaagagctggtgatggcgatgaaggtacgcggcggctggtac
ggcgcggacacctgcatcgatacgcgcaagctgctggagacttcgcgcctgctgtcgcgc
atcaccggcatccaggtgcagcgcaacaaggcgatcgtcgggctgaacgcgttcgcgcat
gaatccggcatccaccagcacggcatgctgaagaaccgcgacacctacgaaatcatgcgc
ccgcaggacgtgggctggcccgattcgcaactggtgctgggccgccacagtggccgcgcc
gcggtcgccgaccgcctgcgccagctgggctatgtgctggaagacgaacagctcgaccaa
gtgatcgccggcgccaaggcgttgacccaaacccagcacgtgatcggcgatgccgacctg
caacggctggtcgaaggcgagcgttacggccccggctggcgcatctccgcgctgagcctg
accgactacggccagcacacccgcgcgcacgtcgacctgtccgatcccgacggcaagcac
ctgctgcaaagcgcggaaggcgaaggcccgatcgccgccgtgttcgccgcgctggcgcaa
gccaccggcgtcgatttcgaactggaaagctacgaagtgcacagcatgggcatcggccgc
gacgcgcgcggcgaagccaacctgagcggtcgcatcgatggcgaaacattgagcgggcaa
ggcaccagtcgcgacgtgctggaagccagcgcgatcgcctggctggatgtcgccaaccgc
gtgctgcgcgcacgccaggcgcagccacgcgtggaggctgcgtga

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