Thermomonas sp. HDW16: G7079_09515
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Entry
G7079_09515 CDS
T06498
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
theh
Thermomonas sp. HDW16
Pathway
theh00260
Glycine, serine and threonine metabolism
theh00261
Monobactam biosynthesis
theh00270
Cysteine and methionine metabolism
theh00300
Lysine biosynthesis
theh01100
Metabolic pathways
theh01110
Biosynthesis of secondary metabolites
theh01120
Microbial metabolism in diverse environments
theh01230
Biosynthesis of amino acids
Module
theh_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
theh_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
theh00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
G7079_09515 (thrA)
00270 Cysteine and methionine metabolism
G7079_09515 (thrA)
00300 Lysine biosynthesis
G7079_09515 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
G7079_09515 (thrA)
Enzymes [BR:
theh01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
G7079_09515 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
G7079_09515 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
CON_HrpB
Motif
Other DBs
NCBI-ProteinID:
QIL20954
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All DBs
Position
2048943..2051444
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AA seq
833 aa
AA seq
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MNALPARDDSEPSKQPAVQCRVHKFGGSSLADAGRIRHVAGLMLESDDPRQVVVVSAMQG
VTDALIGIANAAAEGADWQPALDSLQQRHLDAANALLDAPVETQDWLATQFAQLAELLRA
VGLLRQPGRAAFERIQGMGEVLSSRLLQAHLRERGGDYALLDAREVLVVQPGELGVIVDW
DASAQRLSAWRQAHPQTRAVATGFVAGGKDGLPTVLGRNGSDFSAAIFAALFDADELHIW
SDVDGVLSADPRLVPEAVSLTAMSYQEACELAYFGAKVIHPQTMTPAIARGLPILMRNTF
NPDFAGTRIDANGGAGGPVKGLTLNTDLALVSLEGAGLIGVPGTAERVFAALHATRISVV
MISQGSSEHSICSVVRENDASAARDVLLDEFARELASAQVQGVQVVPGISVLAAVGDGMA
GTPGIAAQLFGALARARVNIRAIAQGASERNISVAIAAEDQTRALRAAHAAFWLSPQTVA
LAVIGPGKVGAALLDQLQAALPRLRSEANIDLRLRALATSSKLWLSEHRDSKDWRTRMNE
APTATDLSAIASHLLDTHMPHAAIIDCSASSAVAEHYPQWLAAGIHVITPNKQAGAGPLE
RYESIRAARAHSGARFRYEATVGAGLPVISTLRDLLDTGDELIAIDGIFSGTLAWLFNKF
DGSAPFSELVREAHALGYTEPDPRDDLSGMDVARKLTILAREAGMPLSLSDVEVESLVPE
ALRDADRDGFMAGLESLDAPMLQRLQAARERGCVLRYVARLQADGSAKVALLELPNDHAF
AHLRLTDNCVQFTTRRYCDNPLIVQGPGAGPEVTAAGVFSDLLRLSAALGARL
NT seq
2502 nt
NT seq
+upstream
nt +downstream
nt
atgaacgctttgcccgcgcgggacgattcagaaccatccaaacagcccgccgtgcagtgc
cgcgtgcacaagttcggcggcagttcgctggcggatgccgggcgcattcgccatgtcgcc
ggactgatgctggagtccgacgatccacggcaagtcgtggtggtgtcggcgatgcagggc
gtgaccgatgcattgatcggcatcgccaatgccgcagccgagggcgccgactggcaaccc
gcgttggacagcttgcagcaacgacatctggatgccgcaaacgcgctgcttgatgccccg
gtagaaacgcaagattggcttgcaacgcagttcgcgcaactggccgaacttctgcgcgcg
gttggcctgctgcggcaacccgggcgcgccgccttcgaacgcatccagggcatgggcgag
gtgctgtcctcgcgcctgttgcaggcgcacctgcgcgaacgcggcggcgattacgccctg
ctggatgcgcgcgaggtgctggtggtgcagcccggcgaactcggcgtcatcgtcgattgg
gacgcgagcgcacagcgactttccgcatggcggcaggcgcacccacaaacgcgcgcggtg
gccaccggcttcgtcgccggcggcaaggacggtctgccgacggtgctgggccgcaacggc
agcgatttctccgcggcgatcttcgccgccctgttcgatgccgacgaactgcacatctgg
tcggacgtcgatggcgtgctgtccgccgatccgcgattggtgccggaagcggtctcgctg
accgcgatgagctaccaggaagcctgcgaactggcctatttcggcgcgaaagtgatccat
ccacagacgatgaccccggccatcgcacgcggcctgccgatcctgatgcgcaataccttc
aatcccgatttcgcgggcacgcggatcgatgccaatggtggcgccggcggcccggtcaaa
ggcctcacgctgaacacggatctcgctctggtcagcctggaaggcgccggcctgatcggc
gtgcccggcaccgccgagcgcgtgttcgccgcgttgcatgcgacacgaatctcggtggtg
atgatctcgcagggctcatccgagcattcgatctgctcggtggtacgcgaaaacgacgcc
tccgccgcgcgcgacgtactgttggacgaattcgcgcgcgaactcgcttccgcacaggtg
cagggcgtgcaggtggtgcccggcatcagcgtgctggccgcggtcggcgacggcatggcc
ggcacgccgggcatcgccgcgcagctgttcggcgcgttggcgcgggcacgggtgaacatc
cgtgcgattgcccagggtgcgtccgaacgcaacatttccgtcgccatcgccgccgaagac
cagacccgcgccctgcgtgctgcacacgccgcgttctggttgtcgccgcagacggtggca
ctggcggtgatcggcccgggcaaggtcggcgccgccctgctcgaccagctgcaggccgcg
ttaccgcgcctgcgcagcgaagccaatatcgacctgcgcctgcgcgcgctcgccaccagc
agcaagctgtggctgagcgagcatcgcgacagcaaggactggcgcacgcgcatgaatgaa
gcccccactgccaccgatctgtccgccatcgccagccatttgctggacacccacatgccg
cacgccgcgatcatcgattgcagcgccagcagcgcggtggccgaacactatccgcagtgg
ttggcggccggcatccacgtgatcaccccaaacaagcaggccggcgcgggcccgctggaa
cgctacgaatccatccgcgccgcgcgtgcgcacagtggtgcgcgcttccgctacgaagcc
acggtcggcgccggcctgccggtgatctccaccctgcgcgacctgctggataccggcgac
gaactgatcgccatcgacggcatcttctccggcaccctggcctggctgttcaacaagttc
gacggcagcgcgccgttctccgaacttgtgcgcgaggcgcatgcactgggctataccgaa
cccgatccgcgcgacgacctgtccggcatggacgtggcgcgcaagctgaccatcctcgcc
cgcgaagccggcatgccgctgtcgctttccgatgtcgaagtggaaagcctggtgccggag
gccctgcgcgatgccgatcgcgacggcttcatggccgggctggaatcgctggacgcgcca
atgctgcagcgcctgcaggccgcgcgcgaacgcggctgcgtgttgcgctacgtggcgcgc
ctgcaagccgacggcagcgcaaaggttgcgttgctggaactgccgaacgaccatgccttc
gcccacctgcgactgaccgacaactgcgtgcaattcaccacccgccgctactgcgacaac
ccgttgatcgtgcaaggccccggcgcgggcccggaagtgaccgcggccggcgtgttctcc
gacttgctgcgcctgtccgccgcgttgggagcgcgcttgtga
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