Thermomonas sp. HDW16: G7079_12940
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Entry
G7079_12940 CDS
T06498
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
theh
Thermomonas sp. HDW16
Pathway
theh00280
Valine, leucine and isoleucine degradation
theh00640
Propanoate metabolism
theh00785
Lipoic acid metabolism
theh01100
Metabolic pathways
theh01110
Biosynthesis of secondary metabolites
theh01210
2-Oxocarboxylic acid metabolism
Module
theh_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
theh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
G7079_12940 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
G7079_12940 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
G7079_12940 (pdhA)
Enzymes [BR:
theh01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
G7079_12940 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
HTH_41
Motif
Other DBs
NCBI-ProteinID:
QIL21568
UniProt:
A0A6G7ZXV6
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Position
2729712..2730785
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AA seq
357 aa
AA seq
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MTLAASFEIEYLQYLKPDGTLAAPLPPAVPDAAALLPLFKQMLFVRTFDTKAIALQRTGK
LGTYAACLGHEATHVGIGASMQPEDVFAPSYREYGAQFMRGVRPREVLMYWGGDERGNDF
EGPRNDYPWCVPISTQCLMASGAALAFKLRGEKRVAVATCGDGGSSKTDFYAAVNSAGAY
SLPVVLCVINNGWAISVPRKAQTGAQTLAQKGLAGGLHCLQVDGNDLVAVLEALRRAHER
ARNGEGGSVIEFMTYRLHDHTTADDARRYRGEEEVKAAWLKEPFLRLRKFLTDNKLWDEE
QEKAWIEECGKMVDVEINAYLETPVQPVEAMFDYLYGDMPADVMAQREQAIAAEKRA
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atgaccttggcggccagtttcgaaatcgaatacctgcaatacctcaagccggacggcacc
cttgccgcgccgttgccaccggcggtgccagacgcggcagcgctgttgcccttgttcaaa
cagatgctgttcgtgcgcaccttcgacaccaaggccatcgccctgcagcgcaccggcaag
ctgggcacgtatgcggcctgcctggggcatgaggccacccatgtcggcatcggcgcctcg
atgcagccggaagacgtgttcgctcccagctaccgcgaatacggcgcgcagttcatgcgc
ggcgtgcgcccgcgcgaggtgctgatgtactggggcggcgacgaacgcggcaacgatttc
gaaggcccgcgcaacgactacccgtggtgcgtgccgatctccacccagtgcctgatggcc
tccggtgccgcactggcattcaagctgcggggcgagaagcgggtggcggtcgcgacctgc
ggcgatggcggctcctccaagaccgatttctacgccgcggtgaattccgccggtgcctat
tcgctgcccgtggtgctgtgcgtgatcaacaacggctgggcgatcagcgtgccgcgcaag
gcgcaaactggcgcgcagacactggcgcagaagggcctggccggcggcctacactgcctt
caggtggacggcaacgacctggtcgccgtgctcgaagccctgcgtcgcgcccacgaacgc
gcacgcaacggcgaaggcggcagcgtgatcgaattcatgacctatcgcctgcacgaccac
actaccgccgatgacgcgcgtcgttatcgtggcgaggaagaagtgaaagccgcatggctg
aaggaacccttcctgcgcctgcgcaagttcctcaccgacaacaaactgtgggacgaggaa
caggaaaaagcctggatcgaggaatgcggcaagatggtcgatgtcgagatcaacgcctac
ctggaaaccccggtgcagccggtggaggcgatgttcgattacctgtacggcgacatgccg
gcggacgtgatggcgcaacgcgaacaggccatcgccgcggagaagcgcgcatga
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