Thermoflavifilum sp.: IMW88_02665
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Entry
IMW88_02665 CDS
T09844
Name
(GenBank) bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase
KO
K01798
Alr-MurF fusion protein [EC:
5.1.1.1
6.3.2.10
]
Organism
theo
Thermoflavifilum sp.
Pathway
theo00300
Lysine biosynthesis
theo00470
D-Amino acid metabolism
theo00550
Peptidoglycan biosynthesis
theo01100
Metabolic pathways
theo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
theo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
IMW88_02665
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
IMW88_02665
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
IMW88_02665
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
IMW88_02665
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
theo01011
]
IMW88_02665
Enzymes [BR:
theo01000
]
5. Isomerases
5.1 Racemases and epimerases
5.1.1 Acting on amino acids and derivatives
5.1.1.1 alanine racemase
IMW88_02665
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
IMW88_02665
Peptidoglycan biosynthesis and degradation proteins [BR:
theo01011
]
Precursor biosynthesis
Amino acid ligase
IMW88_02665
Racemase
IMW88_02665
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ala_racemase_N
Ala_racemase_C
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QOR76472
LinkDB
All DBs
Position
644342..646849
Genome browser
AA seq
835 aa
AA seq
DB search
MPAYSLEQIAAITGGTCIGQTDARNLITRLCIDSRSIVDAAHALFIALKGITRDGHDFID
EAYSKGIRYFLISKAISSARFPDATFVQVTDTLLALQQLAAYHRSRFQIPVIGITGSNGK
TIVKEWLFQLLAKDYYIVRSPKSYNSQIGVPLSVWQMEDMHQLAIFEAGISRKGEMEKLA
SIIRPTMGIFTNIGDAHQEGFSSIEQKVEEKMLLFTDVQLLIYRKDYPWIRQAVIDLQKR
RKAAQKPIEIFDWSTHEEARLQVIAISRRQTHIQVDIRYQQSIHALQIPFTDEGSFENVL
HGVCLMCWMGYDWDTIQERVSRLQPVEMRLSLKHGIHGCIVINDSYNSDLHSLTIALDFL
QQQSTGLKKTLILSDVLQSGRSEQDLYQQIADLIRQKGVERFIGIGPQLMKNQHFFEGIP
GLRCRFYPGTAAFMKDFSPDDFQQEAVLLKGARIFAFEQISRLLEQRLHETILEINLQAI
VHNLKLFQRLLKPGVQMMAVVKAFSYGSGSVEIASLLAYHGVHYLAVAYADEGIALRKGG
IRLPILVMNPEPGSFQAMIQWYLEPEIFTLAQFRQFVREVQQAGKSEFPIHLKLDTGMHR
LGFEQAQLPGLIDALQQAHPYIRVASIFSHFAASEDPAHDSFTALQASLFESMSRQLMQA
LPYRVKRHIGNSAAIHRHPQWQYDMVRLGIGLYGVDGDPEIQHQLQPVATLKTTIAQIKH
LMPGESVGYGRAAKVQKPTTIATVRIGYADGYPRRLSHGRAWMLVHGQPAPTIGWICMDM
LMLDITAIPNAKEGDEVIVFGEDLPIQQVARWADTIPYEIMTTISQRVKRVYYQE
NT seq
2508 nt
NT seq
+upstream
nt +downstream
nt
atgcctgcttattcactcgagcaaatcgcagcaattactggcgggacatgcatcggtcag
actgatgcccgtaacctcattacccgattatgcatagacagccggagcattgtcgatgca
gcacatgcattattcatcgcacttaagggaataacacgcgatggacatgattttatagat
gaggcttacagcaagggtatccggtattttttaatcagcaaggctatatcatcagcaaga
tttccggatgcaacatttgttcaggtaacggatacattgttagccttacaacaactggct
gcctatcatcgcagtcggtttcagattcccgtaatcggcatcacgggtagcaacgggaaa
acgattgtaaaagaatggctattccagttgctggcaaaagactattatattgttcggagt
ccgaagagctataattcacagattggcgtgccgctttcagtgtggcaaatggaagatatg
caccaactggccattttcgaagcaggcatctcccgcaagggtgaaatggaaaagctggct
tccattattcggcccaccatgggcatttttaccaatatcggcgacgcccatcaggaaggg
ttttccagcatcgagcaaaaagtggaggagaagatgttgttgttcacagatgtgcaattg
ttgatttatcggaaggattatccatggattcggcaggcggttatagatttacagaaacgc
cgaaaagcagctcaaaaacctattgaaatatttgactggtcgacacatgaagaagcgcga
ttacaggtgattgccatatcaagacgtcagacccatatccaggtggacatccgctatcaa
caaagcatccatgcactgcaaataccgtttaccgacgagggttcgtttgagaacgtcctc
catggcgtatgcctgatgtgctggatgggatatgattgggatactatacaggagcgcgtt
tcccgcctgcagcccgttgaaatgcggctttccctgaaacacggcatacatggatgcatc
gtcatcaacgacagctacaatagtgacctgcactcgctgacaatagcgctggatttttta
caacagcaatcaaccggattaaaaaaaacgctcatactgagcgatgtactgcaaagcggg
cgtagcgaacaggacctctatcaacagatagccgatctgatacggcaaaagggcgtggaa
agatttatcgggattggtccacaactgatgaagaaccaacatttttttgaaggcataccc
ggcctcagatgtcgcttttatcccggtactgctgcattcatgaaagatttttcgcccgac
gatttccaacaagaagctgttctgctgaaaggcgccagaatatttgctttcgaacaaatt
agtcgtctgctggaacaacggctgcacgaaaccattcttgaaatcaacctgcaggccatt
gtgcataacctcaaattgtttcaacgcttgctgaagcccggtgtgcagatgatggcggtg
gtgaaggccttttcctacggcagcggcagtgtggaaattgccagtctgctggcttatcat
ggggtgcattacctggccgtagcctatgccgatgaaggtattgcgctgcgcaagggtggc
attcgattacccattctggtcatgaatcccgagccgggaagttttcaggctatgattcaa
tggtacctggaacccgaaattttcacgcttgcgcagttcaggcaattcgtccgtgaagtg
caacaggccggcaaatccgaatttcctattcatctgaaactcgataccggaatgcacagg
ctggggtttgagcaagcccagctgcccggactcatcgatgcattacagcaggcacatcca
tatatccgggtggccagcattttcagccattttgcggccagcgaagatccggcgcacgac
agcttcaccgccctgcaggccagcttatttgaatccatgagccggcaactcatgcaggcc
ctgccctatcgcgtaaaacggcatatcggcaacagtgccgccatccaccgccatccgcag
tggcaatatgatatggtgcgactgggcatagggctatacggtgtggacggcgatcctgaa
atccagcatcaactgcagccagtagcaacccttaaaaccaccatagcccagattaaacac
ctcatgccgggcgaatcggttggctatggcagggcggcgaaggtgcaaaaacccactacc
attgccactgtacgcattggttatgccgatggctatccgcgtcgtctgagccatggccgt
gcgtggatgcttgtccacggccagcccgcaccaactatcggctggatctgtatggacatg
ttgatgctcgatatcacggccatacccaacgccaaagaaggtgatgaagtgattgtgttc
ggcgaagacctgccgattcaacaggtggctcgatgggcggataccattccttacgaaatc
atgaccaccatatcgcaacgcgtcaaaagggtatattatcaggaataa
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