Thermoflavifilum sp.: IMW88_09040
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Entry
IMW88_09040 CDS
T09844
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
theo
Thermoflavifilum sp.
Pathway
theo00010
Glycolysis / Gluconeogenesis
theo00020
Citrate cycle (TCA cycle)
theo00620
Pyruvate metabolism
theo00785
Lipoic acid metabolism
theo01100
Metabolic pathways
theo01110
Biosynthesis of secondary metabolites
theo01120
Microbial metabolism in diverse environments
theo01200
Carbon metabolism
theo01210
2-Oxocarboxylic acid metabolism
Module
theo_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
theo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
IMW88_09040 (pdhA)
00020 Citrate cycle (TCA cycle)
IMW88_09040 (pdhA)
00620 Pyruvate metabolism
IMW88_09040 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IMW88_09040 (pdhA)
Enzymes [BR:
theo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
IMW88_09040 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
QOR75485
UniProt:
A0A7M1T6Z2
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Position
2113243..2114361
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AA seq
372 aa
AA seq
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MGCGSFAAGLLVYWAKTCRFAGKFGLHVQTKESKPQVKVAREATQLFGKETYLYWYELML
LIRRFEEKAGQLYGMQKIRGFCHLYMGQEAVAAGAMTATRPDDKFITAYRDHGLAIAKGI
SPKACMAELYGKITGCSKGKGGSMHFFSREHNFFGGHGIVGGQIGVGAGLAFAEKYKGTD
HVVLCFFGDGAARQGILHETLNLAALWDLPVVFICENNEYAMGTSVQRSSKTVDIYRYAD
SYAIPGEAVDGMNPESVHIGIEKAVRRAREGKGPSLLEIKTYRYRGHSMSDPAKYRSKEE
VEEYKKRDPITQVLQVIQKHNWATEQEIEAIEEKVKREIDEAVQFAEESPWPDESELYRD
VYVQPDYPFIVD
NT seq
1119 nt
NT seq
+upstream
nt +downstream
nt
atgggttgcggatcgttcgctgcgggtttgttggtctattgggcaaaaacttgtaggttt
gcaggcaaattcggtttacacgtgcaaacaaaagaaagcaaaccacaggtaaaggtagcc
cgggaagcgactcagctctttggaaaagaaacttatctgtactggtatgagctgatgttg
ctgattcgccgctttgaagaaaaggcgggtcagctttacgggatgcaaaaaatcagaggt
ttctgtcatctctacatgggtcaggaagccgtagcagctggcgccatgaccgccacccgg
cccgatgataaattcattaccgcttatcgtgatcacggattggccattgcgaagggaata
tcgcccaaggcctgcatggccgagctttatggtaaaatcaccggatgctcgaaagggaag
ggcggcagcatgcatttcttttcgcgtgaacacaatttttttggcggacatggcattgtg
ggtggacagattggtgtgggcgccggactggcctttgcagaaaaatacaaaggcaccgat
catgtggtgctttgcttttttggtgatggagccgcgcgtcagggtattttgcatgaaacc
ctgaatcttgctgccttgtgggatttgcccgtggtgttcatctgtgaaaataatgaatat
gcgatgggcacctccgtacaacgcagctctaaaacggttgatatttatcgatatgccgat
tcttatgccattcccggagaggctgtagatggcatgaatccggagtccgtacatatcggc
atcgaaaaagccgttcgtcgtgcaagagaaggcaaaggtcccagcctgctggaaatcaaa
acctatcgttatcgtggccactcgatgagcgatcccgccaagtatcgctccaaagaagaa
gtggaagaatacaaaaaacgcgatcccatcacccaggtacttcaggtgattcaaaaacat
aactgggccactgaacaagaaatagaggccatcgaggaaaaggtgaagcgtgaaatcgac
gaagccgttcaatttgctgaagaatcgccctggccggacgaaagcgaattgtatcgcgat
gtttacgtccaacccgattatccctttattgtagattga
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