Thermaerobacter sp. PB12/4term: DYI95_004320
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Entry
DYI95_004320 CDS
T06418
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thep
Thermaerobacter sp. PB12/4term
Pathway
thep00300
Lysine biosynthesis
thep00550
Peptidoglycan biosynthesis
thep01100
Metabolic pathways
thep01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thep00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DYI95_004320
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DYI95_004320
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DYI95_004320
Enzymes [BR:
thep01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DYI95_004320
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QIA26842
UniProt:
A0A8T8D6N6
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All DBs
Position
1058167..1059594
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AA seq
475 aa
AA seq
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MRLAMAEVAEATGGRLVAGDGGVTVAGGSVDSRRVEAGNLFFALPGQRVDGHQFVEQALA
AGARGAVIARPLAEVLPGGPPPGTAVVEVADTRQALASLARWVRRRRPDLRVVGITGSVG
KTTTKEMAAAVLEQRFAVLKTAGNYNTDIGLPLTLLDLEAHHQVAVLEMAMRGLGEIARL
ASIAEPDIGVVTVVAESHLEFLGSLEKIAQAKGELVEALPPEGVAILNAGDPRVRSMATR
TRARVLTFGLERDAAVRAVAVESRGPGTRFRLEIPGGDAATVELALPGPAAVTCALAAAA
VGVVLGLDAATIAAGLSRARPASLRNEIRQAGSWTLFIDCYNASPTSTAAALQTLRQVAG
DRRAVAILGDMFELGDWAEEGHRQTGQAAARSVDVLLAVGRWAPALVEGWRQAGGAAGAA
AAYPDKAALLAELDRWLQPGDAILIKGSRGMAMEEVAGALVARAGAAGSAPGAEG
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgcggcttgccatggcggaggtcgcggaggccaccggcgggcgcctggtggccggcgac
ggcggcgtgaccgtggccggcggttcggtcgacagccggcgggtcgaggcggggaacctg
ttcttcgcgctgccgggacagcgggtcgacgggcaccagttcgtcgagcaggcgctggcg
gcgggggcccggggagcggtgatcgcccgccccctggcggaggtgctgcccggcgggccg
ccgccgggcacggcggtggtggaggtggccgatacgcgccaggccctggccagcctggcc
cgctgggtgcgccgccggcggcccgacctgcgggtggtggggatcacgggcagcgtgggc
aagaccaccaccaaggaaatggccgccgcggtcctggagcagcgcttcgccgtgctgaag
acggcggggaactacaacacggacatcggcctgcccctcaccctgctggacctggaggcc
caccaccaggtggcggtgctggagatggccatgcgggggctgggcgagatcgcccggctg
gcctccattgccgagcccgacatcggcgtggtgacggtggtggccgaatcccacctggag
ttcctcggcagcctggagaagatcgcccaggccaagggcgagctggtggaggcgctgcca
ccggagggcgtggcgatcctcaatgccggtgacccccgggtgcgctccatggccacccgg
acccgggcccgggtgctcaccttcgggctggaacgcgacgccgccgtccgggcggtggcg
gtagagagccggggtcccggcacccggttccggctcgagattccgggtggcgacgccgcc
acggtcgaactggccctgccggggcctgcggccgtgacctgtgccctggcggcagcggcg
gtgggtgtggtgctgggactggatgcggccaccattgcggcgggcctgagccgggcgcgg
cccgcgtccctgcgcaacgagatccggcaggccggttcgtggaccctcttcatcgattgt
tataatgcctcgccaacctcgacggctgcggccctgcaaaccctgcggcaggtggccggg
gaccggcgggccgtggccatcctgggtgacatgttcgaactgggggactgggcggaagag
gggcatcgccagacgggacaggcggccgcccgcagcgtcgatgtgctgctggccgtgggc
cgctgggcgccggccctggtggaaggctggcgccaggccggcggcgcggccggggcagca
gcggcgtatcccgacaaggccgccctgctggcggaactggaccggtggctccagccgggc
gacgccatcctgatcaaggggtcccggggcatggccatggaagaggtggccggcgccctg
gtagcccgggcgggtgctgccggttccgctccaggggcggagggatga
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