Thermodesulfobacterium sp. TA1: F1847_02465
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Entry
F1847_02465 CDS
T06202
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thet
Thermodesulfobacterium sp. TA1
Pathway
thet00300
Lysine biosynthesis
thet00550
Peptidoglycan biosynthesis
thet01100
Metabolic pathways
thet01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thet00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
F1847_02465
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
F1847_02465
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
F1847_02465
Enzymes [BR:
thet01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
F1847_02465
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Peptidase_M27
Motif
Other DBs
NCBI-ProteinID:
QER41662
UniProt:
A0A5P1UZP2
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Position
464670..466073
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AA seq
467 aa
AA seq
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MNIDNHFLTEEIVRAASGILLNGDMSSSFRGISTDTRVIKPGYLFWALKGKNFDGHDFWK
EALDKGAKGLVISRFPSGFRLEELPKTLTVILVKDTLQALGDFAKFWRKKLNFVGVAITG
SCGKTTTKELSFEILSKFFKTYKNLANYNNLIGVPLSILSIKEGTEVAVLELGTNVPGEI
ARLSEIVFPQVSVITCVYPAHLEGLSSLEGVLEEKVSLFKNTDPNGRLVYFYDQENLRER
VKVFNQEKISFGFEEGADLRVQNLSIEGDRLKGEWIFKNQKQPFHLPDIGKHNLLNLLAA
IGIGLSLNLEWEAILEKVEKEISFYQRAKSYKKGRFLVIDDTYNANPGSMRAALELLRDL
SGYLKKVVILGDMLELGPESKKYHEEIGDLAKEVADQGYFIGRNAKFYACTFSPKPCEVF
ETTEQFLENLRFLKLKEMFTEDTAILVKGSRGLRLERVVERLLEELE
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atgaacatagataaccattttttgactgaagagattgtaagggctgcttctgggattttg
ctaaacggagacatgagctcaagttttagagggatttctaccgacaccagggttataaag
ccagggtatttgttttgggctttaaaagggaaaaactttgacggacatgatttctggaaa
gaggctttagataaaggggctaaagggttggttatttctcgttttccttcaggttttaga
ttagaagaattgcctaaaacgttaaccgttattttggtaaaagacactttgcaagcttta
ggagattttgctaaattttggagaaaaaagcttaactttgtaggagtcgccataaccggt
tcttgcggaaagactacaacaaaagaactttcttttgaaattctttccaagttttttaaa
acctataaaaacttagccaactataataacttgataggggtccccctttctattctttct
atcaaagaaggtaccgaggtagctgttttagaactcgggactaacgtccctggcgagata
gcacgtttgtcagaaatagtgttccctcaggtttctgtgattacctgtgtataccctgct
catttagagggtcttagctctttggaaggggttttagaagaaaaagtatctctttttaaa
aacacagaccccaacggaagattggtctatttctatgatcaagaaaacctaagagaaagg
gtaaaggtttttaatcaagaaaagatttcttttggttttgaagaaggggcagacttgagg
gttcaaaatctaagtatagagggagatagacttaaaggggaatggatttttaaaaatcaa
aagcaaccctttcacttgccagatataggtaagcataatcttttaaaccttcttgcagcc
atagggataggtttaagccttaacttagagtgggaagctattttagagaaagtagaaaaa
gaaatttctttttatcaaagggctaagagttacaaaaagggaaggtttttggtgatagac
gatacttataatgccaatccaggctctatgagggcagctttagagcttttaagagacctt
tcaggatatctaaagaaggtggttattttaggagatatgttagagttaggtcctgaaagc
aaaaagtatcatgaggagataggagatctggctaaggaagtagctgaccaaggctatttt
ataggaagaaatgctaaattttatgcctgcaccttttcccctaagccttgtgaggttttt
gaaactacagaacaatttttggaaaacctcaggtttttaaaacttaaagagatgtttact
gaagataccgctattttagtaaaaggctcaaggggattaagattagaaagggtagtagaa
agacttttggaggagcttgaatag
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