Thermodesulfomicrobium sp. WS: TDMWS_09810
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Entry
TDMWS_09810 CDS
T08730
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thew
Thermodesulfomicrobium sp. WS
Pathway
thew00300
Lysine biosynthesis
thew00550
Peptidoglycan biosynthesis
thew01100
Metabolic pathways
thew01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thew00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TDMWS_09810 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TDMWS_09810 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TDMWS_09810 (murF)
Enzymes [BR:
thew01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TDMWS_09810 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BDV00896
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Position
1050886..1052241
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AA seq
451 aa
AA seq
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MRMSMETIAQAVGGAFSGQNVEVTGVTMDSRRVRPGDLFVAVPGTRVDGHDFAKDAIAAG
AVAVLALRPLPVAAPILVVPDTVRALGLLARAWRETTRARVVAVTGSAGKTTVKEVLALA
LSTQGKVGKNPGNFNNQLGLPLSILALDGDEDFWVLEVGISQPQDMDELGAILAPDVALI
TNAGLAHAEALGGVEGVARHKARLLAWLRPGGVGVWNMGCPELHAACAQAGCPSLTFAGR
ADVDADVRVLARHKTPTGFAFTVACADDTVQLQATAACAHAENVAAVVAVARALRVPMTA
VESGLLAFSPQAGRFVCRARGPWVLIDDTYNANPLSMAAAFAEARQMAGARPLVAVLGEM
RELGVHAPDAHRRLGELARAAQCPLVVYRGAHAEAVAAGLGPGAVLCVTDTPKEAWEAFA
ALRLPNAVLLFKGSRGSRMEEFLAYFEERLS
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atgcgcatgagcatggaaaccatcgcccaggccgtggggggggcgttttccgggcagaac
gtggaggtgaccggggttaccatggacagtcgccgcgtccggccgggggacctctttgtg
gcggtgccgggtacccgggtggatggccatgattttgcgaaagacgccattgctgccggt
gcggtggccgtgcttgcgttgcgtccgctgccggtggcagcccccatcttggtggtgccg
gatacggtgcgcgcccttgggcttctcgcgcgggcgtggcgggagacgacccgagcccgg
gtggtggcggtcaccgggtccgcgggcaagaccacggtcaaggaggtcttggccttggcg
ctctccacgcaagggaaggtggggaaaaatcctgggaatttcaacaaccagctggggctg
ccgctctccatcctcgccctggacggggatgaggacttctgggtcctggaagtgggcatc
agtcagccccaggatatggacgaactcggggccatcctggcaccggacgtggccttgatc
accaatgcgggcctggcccatgccgaagccttgggcggggtggagggggtggcccggcac
aaggcgcgccttcttgcctggcttcgccccggtggggtgggggtgtggaacatgggctgc
ccggaactgcacgccgcatgtgcgcaggctggctgcccgtcgctgacctttgccggccgc
gcggacgtggatgcggacgtgcgggtccttgcgcggcacaagacccccacgggatttgcc
tttactgttgcttgcgccgacgacacggtgcagctacaggccacggccgcctgtgcgcac
gcggagaacgtcgctgccgtggtggcggtggcccgtgctttacgggtgcccatgacggcg
gtggagagtgggcttttggcgttttccccgcaggcgggacggtttgtgtgccgcgcgcgt
ggcccatgggtgctcatcgacgacacctacaacgccaatcccttgtccatggccgcggcc
tttgccgaggccaggcagatggccggcgcccgtcctttggtggcggtgctcggagaaatg
cgggagctcggcgtccatgccccagatgcccatcgccgtttgggcgagctggcccgtgcg
gctcagtgtccattggtggtgtatcgaggggcgcatgccgaggcggtggccgcgggcctt
ggcccaggggctgtgttgtgtgtcacggacaccccaaaggaggcatgggaggcctttgct
gcccttaggctgccgaacgccgtgcttttgttcaaaggctctcgggggagccgtatggaa
gaatttttggcgtattttgaggagcgtctttcgtga
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