Thermococcus sp. 5-4: CDI07_02195
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Entry
CDI07_02195 CDS
T05088
Symbol
topA
Name
(GenBank) DNA topoisomerase I
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
thh
Thermococcus sp. 5-4
Brite
KEGG Orthology (KO) [BR:
thh00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
thh03032
]
CDI07_02195 (topA)
03400 DNA repair and recombination proteins [BR:
thh03400
]
CDI07_02195 (topA)
Enzymes [BR:
thh01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
CDI07_02195 (topA)
DNA replication proteins [BR:
thh03032
]
Prokaryotic type
DNA Topoisomerases
CDI07_02195 (topA)
DNA repair and recombination proteins [BR:
thh03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
CDI07_02195 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Toprim
Zn_ribbon_Top1
ADK_lid
DUF4364
Motif
Other DBs
NCBI-ProteinID:
ASA77150
UniProt:
A0A1Z2TL27
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All DBs
Position
383769..385925
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AA seq
718 aa
AA seq
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MVTLIIAEKPNVARKIAYALAEGKPVRKTIGKVPYYEFTRDGKRIIVAPAVGHLFSLAPK
TKTYGYPVFDIEWVPVYAAEKGKSYAKDYIKALATLAKRADEFVVACDYDTEGEVIGYTA
LKYACGVDPSRAKRMKFSALTKKDLLRAWYNIEPTINFGMADAGIARHVLDWYWGVNLSR
ALTSAIKRASGKWQVLSTGRVQGPTLKFLVDREREIANFKPTPYWVIKMLLEKNGEQYTA
VYEKERILDEDEAKRIVEEAKKGPAFVEKVEVKQQNRHPPVPFDLGTLQREAYSAFGYSP
KKTLEIAQKLYEKGYTSYPRTSSQKLPKNLNFRSILQNLAKLPEYKPFAHELLGKERLRP
VEGKKDDPAHPAIYPTGELPKQGELTKDESNLYDLIVRRFLALFMEPAVREIMKVVINSN
SHRFILGGARTVKEGWLKVYGKYVKFDEVILPAFREGEPVKVIQIKREKKKTKPPARYSP
AAVIKRMEDLGIGTKATRAQILETLYSRGYIEGKRKIKVTPLGMRVVEALEKNVPDIVSV
ELTRAFEEKMEEIMAGKADKEGIIEESKNQLIKILKVFKEREMDIGKMLMETTGTGATTS
KTAARKAGAVKELSEEEEMAVKKAVDGEEKKGPLVIGKCPKCGGDLVVRYNRRTGKRFVG
CSNWPKCNVTYPLLQRGEIIPTNKTCCGGAPVVKIREKGREYEICVDMNCRDWKKGKK
NT seq
2157 nt
NT seq
+upstream
nt +downstream
nt
atggtcacgctcatcatagccgagaaacccaacgtcgcgagaaaaatcgcctatgcccta
gccgagggcaagcccgttagaaagacgatcggcaaggttccctactacgaattcacccgc
gacgggaagaggataatcgtcgctcctgcggttggccacctcttctcgctcgcgccgaag
accaaaacctacggttacccggtcttcgacatagaatgggttcccgtttatgcggcggag
aaggggaagagctacgccaaggactacatcaaggcattagcaacgctcgccaagcgcgcc
gacgagtttgtggtcgcctgtgactacgataccgagggtgaggttataggctataccgcc
ctcaagtacgcctgcggcgttgacccgtcccgggcgaagagaatgaagttctccgcccta
acgaagaaagaccttctcagggcgtggtacaacatcgaaccgacgataaacttcggaatg
gccgatgccggaatagcgcgccacgtcctcgactggtactggggcgtgaacctctccagg
gcgctcacctccgccataaagcgcgccagcggtaagtggcaggttctctccaccggccgt
gttcaggggccgacgcttaagtttctggttgacagggagagggagatagccaacttcaag
cctaccccctactgggtcataaagatgcttctcgagaagaacggggagcagtacacggcg
gtctacgaaaaggagcgcatactcgacgaggatgaggcgaagcgcatcgtcgaggaggct
aagaagggcccggccttcgttgagaaggtcgaggtcaagcagcagaacaggcacccaccg
gttcccttcgacctcggaaccctgcagagggaggcctattctgccttcggctactccccg
aagaaaaccttggagattgcgcagaagctgtacgagaagggttacaccagctatcccagg
acaagctcacagaagctccccaagaacctcaacttccgctccattctccagaacctcgcc
aagctgccggagtacaagcccttcgcccacgagctcctgggtaaggagcgcctcaggcca
gtcgagggcaagaaggacgaccctgcccatccggccatatatccaacgggagagctgccc
aagcagggggagctgaccaaggacgaatccaacctctacgacctcatcgtcaggaggttc
ttggccctcttcatggagccggccgtcagggagataatgaaggtggtcataaactccaac
tcccaccgcttcatcctgggcggggcgaggacagtgaaggagggctggctgaaggtctac
ggcaagtacgtcaagttcgacgaggtgattcttccggctttcagggaaggcgagccggtc
aaggtcatccagataaagcgcgagaagaagaagacgaagcctccagcgcgctactcaccc
gcggcggttatcaagaggatggaagacctaggcatagggaccaaggccactcgcgcccag
attctggagaccctctacagccgcggttacatagagggcaagagaaagataaaggtcacc
ccgctcggcatgcgcgtcgtcgaagctttggagaagaacgtgccggatatagtgagcgtc
gagctgacgagggccttcgaggagaagatggaggagataatggccggaaaggccgataaa
gagggcatcatcgaggagagcaagaaccagctcatcaaaatcctgaaggtcttcaaggag
agggagatggacatagggaagatgctcatggagacgacgggaaccggtgcgactacctca
aaaaccgccgccagaaaagccggcgcggtaaaggagctcagcgaggaagaggaaatggcg
gttaaaaaggccgttgacggggaggagaagaaaggtccgctcgtcataggaaagtgcccc
aagtgcggcggtgacctcgtggtgcggtacaataggaggacgggcaagcgcttcgtcggc
tgttccaactggcccaagtgcaacgtcacctacccgctcctccagcgcggcgagataatt
ccaaccaacaaaacctgctgcggcggcgctccggtggtcaagatacgtgagaagggccgc
gagtacgagatatgcgttgacatgaactgcagggattggaagaaggggaagaagtag
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