Thiomonas arsenitoxydans: THI_1741
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Entry
THI_1741 CDS
T02347
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
thi
Thiomonas arsenitoxydans
Pathway
thi00290
Valine, leucine and isoleucine biosynthesis
thi00620
Pyruvate metabolism
thi01100
Metabolic pathways
thi01110
Biosynthesis of secondary metabolites
thi01210
2-Oxocarboxylic acid metabolism
thi01230
Biosynthesis of amino acids
Module
thi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
thi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
THI_1741 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
THI_1741 (leuA)
Enzymes [BR:
thi01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
THI_1741 (leuA)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Nuc_deoxyri_tr2
Motif
Other DBs
NCBI-ProteinID:
CAZ88413
UniProt:
D6CSZ4
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All DBs
Position
complement(1725083..1726795)
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AA seq
570 aa
AA seq
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MLKQPNTKYRAFPQIDLKNRTWPDRVITQPPIWMSTDLRDGNQALFEPMDAQRKMRMFKM
LCAVGVKQIEVAFPSASQTDFDFVRELIEGGHIPDDVTIEVLTQAREDLIRRTFDSLRGA
KRAIVHVYNATAPNFRRIVFNVDEAGCTQIAVNAAKLIKQIAAEHPETQWTFQYSPEVFS
GTELPFAVSVCNAVTEVWQPTPENKIIFNLPATVEMSTPNIYADQIEWMHRHLDKRDSII
LSLHPHNDRGCAVAAAELGVMAGADRVEGCLFGNGERTGNVDLVTLALNLYSQGVNPGLD
FSNINAVARTVEECTQLPVHPRHPYAGDLVFTAFSGSHQDAIKKGLAAQRQDALWEVPYL
PVDPADLGRAYDSVIRVNSQSGKGGIAYLLEATYGLVMPRRLQVEFSGVVQKHTDATGAE
VTAQQLWQMFNEEYVQIGQPLHLHSYHLSDHGERQGVRLEIEVDGKRLSLTGEGNGPIDA
AIHALRLPLAVHSYEERALGLGADAKASAVVEMAIAGTATSTYGVGMDANIVTASVRALI
SGANRLLQRLPEAEARQHLESLQAPLRAVA
NT seq
1713 nt
NT seq
+upstream
nt +downstream
nt
atgttgaagcaaccgaacaccaaataccgcgcctttcctcagatcgatctgaaaaaccgc
acctggcccgatcgggtcatcacccagccgccgatctggatgagcactgatctgcgcgac
ggcaatcaggcgctgttcgaacccatggatgcacagcgcaagatgcgcatgttcaaaatg
ctgtgcgccgttggcgtcaagcagatcgaagtggcctttccgtctgcctcgcaaaccgat
ttcgattttgtgcgcgaactcatcgagggcggtcacattcccgacgatgtcaccatcgaa
gtgctgacccaagcgcgcgaagatctcatccgccgcaccttcgactcactgcggggcgcc
aagcgggcgatcgtgcatgtttacaacgccacggccccaaatttccgacgcatcgtgttc
aacgtcgacgaagcgggctgcacgcagatcgcggtgaatgcggccaaactcatcaagcag
atcgctgccgagcacccggaaacccaatggaccttccagtacagccccgaggtgttcagc
ggcaccgagcttccctttgccgtctcggtgtgtaacgccgtgaccgaagtctggcagccc
acgccggaaaacaagatcattttcaacttgccggccacggtcgagatgagcacccccaac
atctatgccgaccagatcgaatggatgcaccgccatctcgacaagcgtgacagcatcatc
ctgtcgctgcatccgcacaatgatcggggctgcgccgtcgcggctgcagagctcggcgtg
atggccggtgccgaccgcgtggaaggctgcctgttcggcaatggcgaacgcaccggtaat
gtcgatctggtcacccttgcgctcaacctctattcacaaggcgtgaacccggggctggat
ttttcgaacatcaacgccgtggcgcgcaccgtggaggaatgcacacagttgcccgtgcat
cctcgccacccctatgcaggtgatctggtgtttaccgctttctccggctcacatcaggac
gccatcaaaaaaggtctggccgcacaacgtcaagatgccctgtgggaagtgccgtatctc
cccgtcgatccggccgatctcggccgcgcctacgattcggtcatccgcgtcaacagccag
tccggcaagggcggcattgcctatctgctcgaagccacctacggtctggtcatgccccgc
cgtttgcaggtcgagttcagcggcgtggtgcagaaacacactgacgccactggcgctgaa
gtcaccgcacaacaactctggcagatgttcaatgaagagtatgtgcagattgggcagccg
ctgcatctgcacagctaccacctcagcgaccacggcgagcgccagggcgttcgcctcgaa
atcgaagtggatggcaaacgtctgagtctcacaggcgaaggcaacggccccatcgacgcg
gccatccatgccctgcgcctgccactggccgtgcacagctatgaagagcgcgcactcggc
cttggcgcggatgccaaagcctcggccgtcgtcgaaatggccatcgcaggaacggccacc
agcacctacggagtgggcatggacgccaacatcgtcaccgcctccgtgcgcgcgttgatc
tccggcgccaaccgcctgctgcagcgcctgccagaagccgaggcgcggcagcatctggaa
tccctgcaagccccattgcgtgctgtagcttga
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