Thiomonas arsenitoxydans: THI_1850
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Entry
THI_1850 CDS
T02347
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (Formylglycinamide ribotide amidotransferase) (FGARAT) (Formylglycinamide ribotide synthetase)
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
thi
Thiomonas arsenitoxydans
Pathway
thi00230
Purine metabolism
thi01100
Metabolic pathways
thi01110
Biosynthesis of secondary metabolites
Module
thi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
thi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
THI_1850 (purL)
Enzymes [BR:
thi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
THI_1850 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
TruB_C
Motif
Other DBs
NCBI-ProteinID:
CAZ88517
UniProt:
D6CT98
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All DBs
Position
1834779..1838786
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AA seq
1335 aa
AA seq
DB search
MHILFFEGASALSAFRQDALQARLRQTAPEIADRVRRIHARYVHAVALDAAPTPALHDKL
EGLLRYGDPYAGPAQGQSLYVMPRLGTLSPWASKATDIARLCGAEVHRVERTVQYRLEAE
SGLLRAAKPLTETELLQLAALLHDRMTETVALQRSELERLFSELPPQPLQHVDVLSGTLD
AGRAALARANVEQGLALSDDEIDYLLDAYRKLGRNPTDVELMMFAQANSEHCRHKIFNAR
FTIDGVDQPHTLFQMIRNTHAVSPQGTVVAYADNASVMEGGTVQAWQPDPATHRYGAQEG
LKHVLMKVETHNHPTAISPFPGAATGAGGEIRDEGATGRGSRPKAGLTGFSVSNLRLPGA
GEPWEAATETFGKPGHTASPLQIMLDGPLGGAAFNNEFGRPNLAGYFRVFEQPVDGKVWG
YHKPIMLAGGLGSIDARMTHKKAFPAGTLLVQLGGPGMRIGLGGGAASSLATGSNATHLD
FDSVQRGNPEIQRRAQEVINACCALGEANPILSIHDVGAGGLSNAFPELVEGAGRGAVFQ
LRDVPLEESGLSPREIWSNESQERYVLAIAPDQQEAFAALCARERCPFAVVGVATQEQTL
IVNDSLHADQPDLARPVDLPLDVLLGKPPRVHRQAQRQLPQGEALDLAEVDLAQACEAVL
RHPTVASKRFLITIGDRTVGGMSHRDPMVGPWQVPVADCAVTLADYAGFRGEAMSVAERA
PVAVLNPAASGRLAVSEAVLNLLAAPVQRLADIKLSCNWMAACGQPGQDAALYDTVHAIG
MELCPALGISVPVGKDSLSMHTRWEDAGQAKSVTSPVSLVVSAFATLPDVRGTLTPQLRT
DAPSSLILVDLGQGKRRMGASILAQTLGKIGDITPDLNSPDLLKSFAEALAELRTAGQVW
AYHDRSDGGLWAAACEMAFAGHCGLSLNVDVLTLEGNEADDWGDAKDWAKQVGPRRHIQT
LRALFNEEPGLLLQVPATQRDAVLQTLRQHGLSAHSHAIGTVNDGDVIEIWRDTQRIYTA
PRTQLQQVWDRVSWRMAMLRDNPECAQAEHDALADAADPGLHLHLTFDAQQDIAAPFIAS
GARPQVAILREQGVNSQVEMAYAMHRAGFDAVDVHMSDLMAGRARLGDFRGFVACGGFSY
GDVLGAGEGWARSILFNPELADQFARFFGRTDTFALGVCNGCQMLAALAPMIPGARAWPR
FTRNRSEQFEARLSLVEVAESPSLFFQGMAGSRAPIAVAHGEGRADFSQQGDAKLLQVAM
RFVDHQGQPTERYPYNPNGSPEGITAVTTPDGRFTALMPHPERVFRSVQMSWTAEDQGDD
SPWMRMFRNARAWCE
NT seq
4008 nt
NT seq
+upstream
nt +downstream
nt
atgcacatccttttctttgaaggcgccagcgccttgtccgcgtttcgccaggacgcattg
caggcccgcctgcgccagaccgcgccggagatcgccgatcgcgtgcgccgtattcatgcc
cgctatgtgcatgcggtggcgctcgacgccgccccgactcccgcgcttcacgacaaactc
gaaggcctgctgcgctatggcgatccttacgccggtcccgcacagggtcagagcctgtat
gtcatgccgcgcctgggcaccctttcgccctgggcttccaaggccaccgacatcgctcgc
ttgtgcggcgccgaggtgcaccgggtggaacgcacggtgcaataccgccttgaggcggag
agcgggctgctgcgcgccgccaaaccgttgaccgagaccgaactgcttcagctcgccgcc
ctgctgcacgaccgcatgaccgaaaccgtggcgctgcagcgcagcgagctggagcgtctt
ttttccgaactgccaccccagccgctgcagcacgtggacgtgctctccggcacgcttgac
gccggccgcgcggcgctcgcgcgtgccaatgtggagcagggactggcgctgtcggatgac
gagatcgactatctgctcgacgcctaccgcaagctcggccgcaaccccaccgatgtcgag
ctgatgatgttcgcccaggccaacagcgaacattgccgccacaaaattttcaatgctcgc
ttcaccatcgatggcgtcgatcagccgcacaccctgttccagatgatccgcaacacccac
gcggtgtcgccgcagggcacggtggtggcctatgccgacaatgcctcggtgatggaaggc
ggcacggtgcaggcctggcaacccgatcccgccacgcaccgctacggcgcacaagaaggg
ctcaagcatgtgctgatgaaggtggaaacgcacaatcaccccaccgccatttcgccgttt
cccggtgcggccaccggagccggtggagagattcgcgacgagggcgccaccggccgtggc
tcgcgccccaaggcggggctcaccgggttttcggtctccaatctgcggctgccgggcgct
ggcgaaccttgggaggcggccacagaaacattcggcaagcccggtcacaccgccagcccg
ctgcagatcatgctcgacgggccgctgggcggcgcggcgttcaacaacgagttcggccgt
cccaatcttgccgggtacttccgcgtgttcgaacaaccggtggacggcaaggtctggggt
tatcacaagcccatcatgctcgccggtggcttgggctccatcgatgcccgcatgacgcac
aaaaaggcatttcccgcaggcacgctgctggtgcagcttggcggcccgggcatgcgcatc
ggcttgggcggcggcgcggcgtcgagtctggccaccggcagcaacgccacccatctcgat
ttcgattcggtgcagcgcggcaacccggaaattcagcgccgggcgcaagaagtcatcaac
gcctgctgcgcgctaggcgaggccaatcccattctgtcgattcacgatgtgggcgctggc
ggactgtccaacgcctttcctgagttggtggagggcgcgggccgtggcgcggtgttccag
ttgcgcgatgttccacttgaagagtctggcctaagtccaagagaaatatggagtaacgaa
agccaggagcgctatgttctggccattgctcctgatcagcaagaggctttcgccgcgctg
tgcgcccgcgagcgctgcccctttgcggtggtgggcgtcgccacgcaagagcaaacgttg
atcgtgaatgacagcctgcacgctgaccagcccgatctggcccgtccggtcgatctgccg
ctggacgtgctgctgggcaagccgccgcgcgtgcatcgtcaggcgcagcggcagttgccg
caaggcgaggcgcttgatctggctgaggtcgatctggcgcaggcctgcgaagcggtgctg
cgccaccccacggtagcgagcaagcgctttctcatcaccattggcgaccgcacggtaggc
ggcatgagccaccgcgatcccatggtcggcccctggcaggtgccggtggccgactgtgcc
gtcacgctcgctgactacgccggatttcggggcgaggcgatgagcgtggccgagcgtgcg
cccgttgcggtgctcaaccccgccgcgtcgggtcggctggcggtgagcgaggcggtgctc
aatctgctggccgccccggtgcaacgtctggccgacatcaagctgtcgtgcaactggatg
gccgcctgcggccagccagggcaggacgccgcgctgtacgacaccgtgcacgccatcggc
atggaactctgtcccgctctgggtatttcggtgcccgtgggcaaggattcgctgtcgatg
catacgcgctgggaagacgcgggtcaggccaagagcgtgacttcgccggtctcgctggtg
gtctccgccttcgccacgctgcccgacgtgcgcggcacgcttacgccgcagctgcgcacc
gatgcgccgagcagcctgattctggtcgatctgggccagggcaaaaggcgcatgggcgcg
agcatcctggcgcagacgctcgggaagatcggcgacatcacccccgatctcaacagcccg
gacttgctgaaatcgtttgcggaagcgctggctgaattgcgcacggcaggtcaagtctgg
gcctatcacgaccgatccgacggcggcctgtgggcggctgcctgcgaaatggccttcgcc
gggcattgcggcctcagcctgaatgtggacgtgctcacgctcgaaggcaacgaagccgac
gactggggcgacgccaaagactgggccaagcaggtcggcccgcgccgtcacattcaaacc
ttgcgcgcactgttcaacgaagagcccggcttgctgctgcaagtgcccgcaacgcagcgc
gacgccgtgctgcagaccctgcggcagcatggcctgtcggcgcacagccacgccatcggc
acggtcaacgacggcgacgtcatcgagatctggcgcgacacgcagcgcatttacaccgca
cctcgcacccaattgcagcaagtgtgggaccgcgtgtcgtggcgcatggcgatgttgcgc
gacaaccccgagtgcgcccaagccgagcacgacgcgctggccgacgccgccgatccgggg
ctgcacttgcacctgactttcgacgcccagcaagacatcgccgcgcctttcatcgccagc
ggggcgcggccgcaagtcgccatcctgcgtgagcagggcgtcaactcgcaggtggaaatg
gcctacgccatgcaccgcgccgggttcgacgcggtggacgtgcatatgagcgacctgatg
gcaggccgcgcccggctgggcgatttccgcggctttgtcgcctgcggcggtttcagctac
ggcgacgtgctcggcgcgggcgagggctgggcgcgttccattctgttcaaccccgagctc
gccgatcaattcgcacgctttttcggccgtaccgataccttcgcgctgggcgtgtgcaac
ggctgccagatgctggccgcactcgcccccatgattcctggcgcccgcgcctggccgcgc
ttcacccgcaaccgctcggagcagttcgaggcgcggttgtcgctggtggaagtcgccgag
tcgccgtccctcttttttcagggcatggctggcagccgcgcgcccatcgctgtggcgcat
ggcgaagggcgggccgatttttcgcagcagggcgacgcgaagctgctgcaggtggccatg
cgctttgtcgatcatcagggccaacccacggagcgttatccctacaaccccaacggcagc
cccgagggcatcaccgccgtgaccacgcccgatggccgctttaccgcgctgatgccgcac
ccggagcgggtgttccgcagcgtgcagatgagctggaccgccgaagaccagggcgacgac
agcccgtggatgcgcatgttccgcaatgcgcgggcctggtgtgagtga
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