Thiomonas arsenitoxydans: THI_2696
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Entry
THI_2696 CDS
T02347
Symbol
folC
Name
(GenBank) FolC bifunctional protein [Includes: Folylpolyglutamate synthase (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase); Dihydrofolate synthase ]
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
thi
Thiomonas arsenitoxydans
Pathway
thi00790
Folate biosynthesis
thi01100
Metabolic pathways
thi01240
Biosynthesis of cofactors
Module
thi_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
thi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
THI_2696 (folC)
Enzymes [BR:
thi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
THI_2696 (folC)
6.3.2.17 tetrahydrofolate synthase
THI_2696 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
CAZ89309
UniProt:
D6CVJ0
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Position
complement(2649738..2651063)
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AA seq
441 aa
AA seq
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MSPTPHTLDGWLAHAELLHARVIDLGLERVQAVRAAMQLQFTCPVITVAGTNGKGSTCAM
LEAILMAAGYRVGVYNSPHLVHFEERCRIAGQTVNAQDLLPHFAAVEQARLTAGVGAAAV
SLSYFEFTTLAILSLLASQRLDAVILEVGLGGRLDAVNIIDTDCAIITSIDLDHMEFLGP
DRESIGREKAGIMRAAKPAIVSDPQAPQSVQDHAEDIGADLWLAGRDFHYTHLPQQWGWQ
GRAQRRHSLAFPALRGANQLLNASGVLAALEALQAALPVAAQAVREGFARAELPGRFQVL
AGQPTLVLDVGHNPHAIAVLAENLDSMGYFPVTHAVFGAMADKDIPGMLRRMLPLIDVWH
LCDLPTPRAASAKELAAHLLALKPDARIAQHPDPLQALRAAAAAVELTDRIVVFGSFYTV
GGVMQEGLPRLHGKHLVSSPQ
NT seq
1326 nt
NT seq
+upstream
nt +downstream
nt
atgtctcccacaccccacactctggacggctggctagcgcacgccgagttgctgcatgcc
cgcgtgatcgacctggggcttgagcgcgtgcaggcggtgcgcgcggccatgcagttgcaa
ttcacctgcccggtcatcaccgtggcgggcaccaatggcaagggctcgacctgcgccatg
ctcgaagccattctcatggcggcgggctaccgcgtgggcgtctacaactcgccgcatctg
gtgcatttcgaggaacgctgccgcatcgcagggcagacggtgaatgcgcaggacttgttg
ccgcatttcgccgctgtcgagcaggcccggctgaccgcaggcgtgggcgccgcggcggtg
agtttgagctatttcgagttcaccaccctggccatactgtcgctgctcgccagtcagcgg
ctcgacgccgtcattctcgaagtcgggctgggcgggcggctcgatgcggtgaacatcatc
gacaccgactgcgccatcatcaccagcatcgacctcgatcacatggagtttctcggtccg
gatcgggagtccatcggccgcgagaaggcgggcatcatgcgggccgcgaagcccgccatc
gtcagcgacccgcaggcgccgcagtcggtgcaggatcacgccgaggacatcggcgccgat
ctctggctggccggacgcgactttcactacacccacctgccgcagcaatggggctggcag
gggcgcgcgcagcgtcggcacagcctggcgtttccggcgctgcgcggcgccaatcagctg
ctcaacgccagcggcgtgctcgccgcgctggaggccttgcaggccgccctgccggtggcg
gcgcaggcggtgcgcgaagggtttgcgcgagcggagctgcccgggcgctttcaggtgctg
gcgggtcagcccacgctggtgctcgatgtgggccacaacccgcacgccatcgccgtgctg
gcggaaaacctcgacagcatgggctactttcccgtcacccacgcggtgtttggcgccatg
gccgacaaagacatccccggcatgttgcgccgcatgttgccgctgatcgacgtctggcat
ctttgcgacttgccgacgccgcgagccgcgtcggcaaaagagctggcggctcacctgctc
gccttgaagccagacgcccgcatcgcccagcatcccgaccccttgcaggcgctgcgcgcc
gcggcggctgccgtggagctgaccgatagaatcgtggtgttcggctccttctacaccgtg
ggcggtgtgatgcaggaggggctgccccgacttcacggcaagcatctcgtttcctccccg
caatga
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