Thiohalobacter sp. COW1: TspCOW1_31440
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Entry
TspCOW1_31440 CDS
T08363
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thic
Thiohalobacter sp. COW1
Pathway
thic00300
Lysine biosynthesis
thic00550
Peptidoglycan biosynthesis
thic01100
Metabolic pathways
thic01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thic00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TspCOW1_31440 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TspCOW1_31440 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TspCOW1_31440 (murF)
Enzymes [BR:
thic01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TspCOW1_31440 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BCO33041
UniProt:
A0A7R7GNU8
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Position
3339744..3341111
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AA seq
455 aa
AA seq
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MIAMALSEAAQVVRGRLQGADTRFAGLSTDSRGLERGNLFVALAGERFDGHDYLDQAAAG
GAAGALVSTAVTELLPCIRVTDTRLALGGLAAAWRARFDIPLVAVTGSNGKTTVKEMLAA
ILGMKHQVLATRGNLNNDIGVPLTLGRLDAVHTAAVIEMGANHPGEIAYLTGLARPTVAL
ITNAGPAHLEGFGSLEGVARAKAEIYDGLGPEGLAVVNRDDAFADYWLMRLQGRRIMTFG
LEMQADVSAEVSPHESGQRLVLRTPAGSIEVELALPGRHNAMNALAAVAAALGAGASLAA
VQSGLQSLRPVGGRLQIHRCADDIGVIDDTYNANPGSVQAALAVLGQLSGERWLVLGDMG
ELGGESRQLHRDIGARAAAAGCDRLFTLGGDAASAAEAFTGPAAHFDDFESLQSALEAQL
HPGVQVLVKGSRSMRMERVVQALLVRLQPRPGGRH
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgattgccatggcgctgtccgaagcggcgcaggtcgtgcggggacggctgcagggcgcg
gatacgcgtttcgccggcctgagcaccgacagccgcggcctggagcgcggcaacctgttc
gtggcgctggcgggtgagcgtttcgacggccacgactatctcgatcaggccgcggccggc
ggtgctgcgggcgcgctggtcagcacggcggtgacggaactgctgccctgcatccgggtg
accgatacccggctggcgctgggtggactggccgcggcctggcgcgcgcgtttcgatatc
ccgctggtggcggtcaccggcagcaacggcaagaccacggtcaaggagatgctggccgcc
atcctgggcatgaaacatcaggtgctggccacccgcggcaacctcaacaacgatatcggc
gtgcccctgaccctgggtcggctggacgccgtgcatacggccgccgtgatcgaaatgggc
gccaaccatccgggcgagatcgcttacctcaccggcctggcccggccgacggtcgcgctg
atcaccaatgccggacccgcccatctggaggggttcggcagcctggaaggcgtggcgcgg
gccaaggccgagatctatgacgggctgggtcccgaaggtctggccgtggtcaaccgcgac
gatgccttcgccgactactggctgatgcgactgcagggccggcggatcatgaccttcggg
ctggagatgcaagccgatgtcagcgccgaagtgtcgccgcatgaatcgggccagcggctg
gttctgcgcaccccggccggcagcatcgaggtcgaactggcgctgccggggcggcacaac
gccatgaacgccctggccgccgtcgctgccgccctgggggcgggcgcctcgctggcggcg
gtgcagtccgggctgcagagtctgcgtccggtcggcggccggctgcagatccaccgctgc
gccgatgacatcggcgtgatcgacgacacctacaatgccaaccccggctcggtgcaagcc
gctctggcggtgctcgggcagctgtccggggagcgctggctggtactgggcgacatgggt
gaactgggcggcgagagccgccagctgcatcgggatatcggcgcccgtgcggccgcggcc
ggctgcgatcggctgttcaccctggggggtgacgccgcgtccgccgccgaggccttcacc
gggccggcggcgcatttcgatgatttcgagtccctgcagtccgcactcgaggcgcagctg
catcccggggtgcaggtgctggtcaagggttcgcgcagcatgcgcatggagcgggtggtc
caggccctgctggtgcggttgcagccacggccgggagggcgtcactga
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