Tetragenococcus halophilus NBRC 12172: TEH_01780
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Entry
TEH_01780 CDS
T01640
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thl
Tetragenococcus halophilus NBRC 12172
Pathway
thl00300
Lysine biosynthesis
thl00550
Peptidoglycan biosynthesis
thl01100
Metabolic pathways
thl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TEH_01780 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TEH_01780 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TEH_01780 (murF)
Enzymes [BR:
thl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TEH_01780 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
HP0268
SSL_OB
Motif
Other DBs
NCBI-GeneID:
11260933
NCBI-ProteinID:
BAK93505
UniProt:
A0AAN1SED2
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All DBs
Position
198258..199601
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AA seq
447 aa
AA seq
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MDLTIKEIAEVLGSSQTSEQKITNVEFDSRKITTGDLFVPLKGTRDGHEFAAYAQESGAI
ATLWSEDVSEAPAGLFVFFVSDTKKAFQKLASYYRQKLAPKVLAITGSNGKTTTKDMTEA
VLAQKYQTYKTQGNYNNELGLPYTILHMPETTEILVLEMGMDHAGDLTLLSQIGQPDAAA
ITLIGEAHIESLGSREGIAKGKMEIAAGLKKDGVLFIPVDEPLLSPLIRPLNQKVVTFGL
KEGMVQAEVLNTTKQSTEFSINGKNFLIPVIGSYNVKNALVAYSFGHYFGLSDEEIAAGL
KNFHLTKDRTQWSKAANGADILSDVYNANPTAMGLVLDSFAELALPGRKIVVLADMLELG
KDSKQMHRQMAKHIDDSLAEVYLYGTDMEALYQVLKDSNQDIFYFTEDRKKEMIEAIKRD
IQAQDSVLLKGSNGMGLAEVIIALQEK
NT seq
1344 nt
NT seq
+upstream
nt +downstream
nt
atggatctaacgattaaagaaattgcagaagtcttgggaagctctcaaactagcgaacaa
aagattacaaatgttgaatttgatagtagaaaaataaccacaggagatctctttgttcct
ttaaagggaacacgagatggccatgagtttgctgcctatgcccaagaaagtggcgcgatt
gctacactttggagtgaagatgtatctgaagcaccagcaggtttatttgtattttttgtg
tcagataccaaaaaagctttccaaaaattagctagttactatcgacaaaaacttgcgcct
aaagttctggcgatcacaggaagtaacggcaaaacaacgactaaagatatgacagaagca
gttttggcgcaaaagtatcaaacgtataaaacacaaggaaattataataacgaattgggt
ttgccttatacgattttacacatgcctgaaacaacagagattttagtcttggaaatggga
atggatcacgcaggtgatttaacacttctttctcagataggccagccagatgcagcagcg
attactttaatcggtgaggctcatattgaaagcttgggctcacgagaaggtattgcaaaa
ggcaaaatggaaattgctgctggtttaaagaaagacggtgtattgtttattcctgtagat
gaacctctattatctccacttattcgtcctttaaatcaaaaagtagtaacttttggttta
aaagaaggaatggttcaagccgaggtattaaatacgacaaaacaaagtactgagttttct
attaatggaaaaaattttttgattcctgttattggaagctataatgtcaaaaatgctctt
gttgcttatagttttggccattattttggactaagtgatgaagaaatcgcagcggggcta
aagaattttcatttaaccaaagatcgtacgcaatggagtaaagccgctaacggagcggat
atactgagcgatgtatataatgcaaatcccacagcgatgggattagtgttagatagcttt
gctgaattagcactgccaggcagaaagattgttgtattggcagatatgcttgaattagga
aaagattctaaacaaatgcatcgccaaatggcaaaacatattgatgattctttggcagaa
gtttatctatatggcactgacatggaagctttgtatcaggtattaaaagatagcaatcaa
gatattttttattttactgaagatagaaaaaaagaaatgatagaagcgatcaaaagagat
attcaagcgcaagattcggtgcttttaaaaggaagtaatggtatgggattggcagaagtt
atcatagctttacaagaaaagtga
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