KEGG   Thermococcus cleftensis: CL1_0035
Entry
CL1_0035          CDS       T02169                                 
Name
(GenBank) putative phosphomethylpyrimidine kinase
  KO
K21219  hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
Organism
thm  Thermococcus cleftensis
Pathway
thm00730  Thiamine metabolism
thm01100  Metabolic pathways
thm01240  Biosynthesis of cofactors
Module
thm_M00896  Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP
Brite
KEGG Orthology (KO) [BR:thm00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    CL1_0035
Enzymes [BR:thm01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     CL1_0035
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.49  hydroxymethylpyrimidine kinase
     CL1_0035
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.7  phosphooxymethylpyrimidine kinase
     CL1_0035
SSDB
Motif
Pfam: Phos_pyr_kin ThiN PfkB Carb_kinase
Other DBs
NCBI-ProteinID: AFL94250
UniProt: I3ZRB6
LinkDB
Position
complement(29035..30330)
AA seq 431 aa
MAVLIVAGLDTGGGAGIKADIETVSALGEHPLPILTAVTYQNPERVSGYFPLPAEALRDQ
IRAVRGHFDIKAVKVGMLGSGGIAKVVAKETEDLTRVFDPVMASSTGERLIDDIGSLKVL
VKGSIVTPNVPEAEALSGLKIHSLEDMRESARIIAQTLKAEAVIVKGGHLNLTDVLYWNG
EFFEFPGERVDGFTHGTGCAFSSALAAFLAKGLELPEAVERAKRFVEGAIRFSKAEAKAV
NPLWEFQRDAHRWRAREELERAVQELVKFGEKLNPHVPEVGTNFALATALGEVFAVKGRI
VRYGKTVKPVGPIELNASDHLRRALLKMREFYPEVRAVLNLRYSGKLVERAERLGFVVSF
YDRREEPEEVKRAERGTMEWGIETAVRRAGKRPDVIYHLGDWGKEPMILIFGRDAREVVE
RVRVLLSPSPR
NT seq 1296 nt   +upstreamnt  +downstreamnt
atggccgttttgattgtagcaggcctcgacaccggcgggggagcgggcattaaagccgac
atcgagacggtctcggctctgggtgagcatccactgccgattctcacagcggtcacctac
cagaaccccgagagggtttccggctattttcccctaccagcggaggccttgagggaccag
atacgggccgttagggggcactttgatattaaggcagtcaaagtgggcatgctcgggagc
ggggggatagccaaggtcgttgccaaggaaacggaggacttaacgagggtcttcgatccg
gtgatggcttcgagcaccggtgagaggctcatcgacgacatcgggtcgctcaaggttctc
gtgaagggctcaatagtcacccccaacgttccggaggccgaagctctaagcggtcttaaa
atccactccctcgaggacatgagggaatcggcgaggatcatagcccaaactctgaaggcc
gaggcggtgatcgtcaaaggcggccacctgaacctaaccgacgtcctctactggaacggg
gagttcttcgagtttcctggggaaagggttgatggcttcacccacgggacgggctgtgcc
ttctcctcggctttggccgcttttctggcgaagggccttgagcttccagaggcggtggaa
agggccaaacgcttcgttgaaggtgctataaggttctcaaaggccgaggcaaaggccgtc
aatcccctctgggagttccagagagacgcccaccgctggagggccagggaagagcttgaa
agggcagttcaagaactcgtgaagttcggcgaaaaactcaaccctcacgttccggaggtg
ggcactaacttcgcgctggcgactgcccttggagaggtcttcgcggtgaagggcaggatc
gtccgctacgggaaaacggttaagcccgtgggcccgattgagctgaacgccagcgaccat
ctgaggagggctttgctcaagatgcgcgagttctaccccgaggtaagggccgtcctgaac
ctgcgctactccgggaagctggtggagagggctgaacggcttggctttgtcgtttcattc
tacgacaggagggaggagcccgaggaggttaagagggccgagagaggaacgatggaatgg
ggcatagagactgccgtaagaagggcaggaaaaaggccggacgtaatctaccacctcggg
gactggggcaaggagccgatgatcctgatcttcgggcgggacgcgcgggaggtggtggag
agagtcagggttctcctttctccctctcctcgatga

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