Thermococcus cleftensis: CL1_0781
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Entry
CL1_0781 CDS
T02169
Name
(GenBank) phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
thm
Thermococcus cleftensis
Pathway
thm00230
Purine metabolism
thm01100
Metabolic pathways
thm01110
Biosynthesis of secondary metabolites
Module
thm_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
thm00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CL1_0781
Enzymes [BR:
thm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CL1_0781
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Gly_transporter
Motif
Other DBs
NCBI-ProteinID:
AFL94986
UniProt:
I3ZTF2
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Position
complement(713257..715398)
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AA seq
713 aa
AA seq
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MFPHEEKLIRERLGRELNELEWAMLEVMWSEHASYKSSRPWLKLLPTENEHVILGPGEDA
GIIRFDDETWIAVGIESHNHPSAVEPYGGATTGVGGIVRDILCMGARPIALLDPIRFGPL
EKERNRYLFEHVVKGIADYGNRIGVPTVGGETEFDESLDNYTLVNVACVGIMRPEHLVHS
YVTESGLKLILVGNRTGRDGIHGVTFASEELGENAEEEDRSAVQIPDPFTEKLLIEATLE
AVYTGKVKALKDLGGGGLTCAASEMAGKKGFGAVIYADRVPLREPGMSVTEVMISESQER
MLFAVSEADVDALGKIFEKYGLEWTVVGEVVEEPRFIIYWKGEKVADMPIELLTNVPTIE
WEMKPYSIEKPAETPDVPFERAFNLVWSSPNVLSKRWVWEQYDHEVQGRTVLKPGRDAAV
LKLNDEYGLAFVADGSPNHSRLNPYQGAMGAVAEVVRNLVGVGAEPLALVDNLNFASPER
PDVYWSFAETVRGLADAAKAFGLAYVSGNVSFYNEIVNRPIKPTPVVAGLGKVKLEEIPE
MGLEEGLLIAVVGFTRPELGGSELYRVFGVEGGFAPRVNLKVERANAEGILKAIRKGLVR
AVHDVSRGGIAVALAEMALSGNTGFTADLSKVPTETSNPIEVAFSESHSRYIVAFPEENL
DALNAIFRDFAVIGRAGGKEAAFLWDGRELLRKPLEELRAIHESLPKLLGEEE
NT seq
2142 nt
NT seq
+upstream
nt +downstream
nt
atgttcccccacgaggagaagctcatccgtgagaggcttgggagagagcttaacgagctc
gaatgggctatgctcgaagttatgtggagtgagcatgcctcatacaagtcgagcaggccg
tggctgaagctcctgccgaccgagaacgagcacgtgattctgggccccggtgaggacgct
ggaataatcaggtttgacgatgagacctggatagcggttggaatcgagagccacaaccac
ccctcagctgtggagccctacggtggagcgacgacgggcgtcggtggaatcgtcagggac
atactctgtatgggtgcaaggccgatagctttgcttgacccgatacgcttcggaccattg
gaaaaggagcggaaccggtatctctttgagcacgtcgtcaagggcatagccgactacggc
aacaggataggtgtcccgacggtcggaggagaaaccgagttcgatgagagcctcgataat
tacaccctcgtcaacgttgcctgcgttgggattatgaggcccgagcacctcgtccacagc
tacgtcaccgagtccggtctcaaactcatccttgtcggtaacagaaccgggagggacggg
attcacggcgtcaccttcgccagcgaggagctgggcgagaacgcggaggaggaagaccgc
tccgcggtgcagattcccgaccccttcacggagaagctcctaatcgaggcgacgctcgaa
gcggtttacactggtaaagtgaaggctctaaaagaccttggcggtggcggtttaacctgc
gccgcctccgagatggcagggaagaagggcttcggcgcggtaatctacgccgacagagtt
cccctccgcgagccggggatgagcgttaccgaggtaatgatttccgaaagccaggagaga
atgctcttcgcggttagtgaagccgacgtcgatgccctcggaaagattttcgagaagtac
ggccttgagtggacggttgttggggaggtcgttgaggagcctcgctttatcatctactgg
aagggcgagaaggtcgctgacatgcccatcgagctcctaacgaacgttccaacgatagag
tgggagatgaagccctacagcatcgaaaagcctgctgagacgcctgacgtccccttcgag
agggccttcaacctcgtctggagcagtccgaacgtcctgagcaagcgctgggtctgggag
cagtacgaccacgaggttcaggggaggaccgtcctcaagcccgggagagacgccgccgtc
ctgaagctcaacgacgagtacggcctggccttcgttgccgacggaagtccaaaccacagc
cgcctcaacccctaccaaggtgcgatgggtgccgtcgctgaagtcgtcaggaacctcgtg
ggcgttggagctgaacccttggccttggtggacaacctcaactttgcctcgcccgagagg
cccgatgtttactggagcttcgccgagacggtgagggggctggccgacgctgccaaggcc
tttggcctggcgtacgtcagcggcaacgtcagcttctacaacgagatcgttaacaggccg
ataaagccgacccccgtcgttgccggcctcgggaaggtaaagcttgaggaaattccggag
atggggctggaagagggcctgctcatcgcggtggtcggcttcacaaggcctgaactcggc
ggttcagaactttacagggtctttggagtcgagggcggctttgccccccgtgtaaacctt
aaggtggagagggccaacgccgaggggattctgaaggctatacggaagggtctcgttagg
gcggtgcacgatgtgagcaggggaggaatagcagtggcgctcgctgagatggccctatct
ggaaacacgggcttcacggcagacctctcaaaggttcccaccgaaacttctaacccaatc
gaggtcgccttcagcgagagccactcccgctatatcgtggccttcccggaggagaacctc
gatgcacttaatgccatcttcagggacttcgccgtcatcggaagggccggcggaaaggag
gcggccttcctctgggacggaagggagctcctccggaagcccctcgaagagctcagggca
atccatgagtccctgccaaagcttctgggtgaggaggaatga
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