Candidatus Thioglobus autotrophicus: SP60_03420
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Entry
SP60_03420 CDS
T04079
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
tho
Candidatus Thioglobus autotrophicus
Pathway
tho00790
Folate biosynthesis
tho01100
Metabolic pathways
tho01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
tho00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SP60_03420
Enzymes [BR:
tho01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SP60_03420
6.3.2.17 tetrahydrofolate synthase
SP60_03420
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
DUF5661
Motif
Other DBs
NCBI-ProteinID:
ALE52354
UniProt:
A0A0M4PMS8
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Position
631756..632946
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AA seq
396 aa
AA seq
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MGGLKTLEQWLAWQESLHSQEIDLGLERIQSVYSRLFPEGVPFTTITVAGTNGKGSTIAL
IESIYQQSIFTVAKFTSPHILSYNERFVMNGIQATDDQICTAFEAIEQVRNNTSLTYFEF
STLAALLIFAEQKIDVAILEVGLGGRLDSTNVVDTDMAVITNIAIDHVDYLGATRELIGH
EKSGIMRANIPCICGDTNPPESLAKHANTVGALLEFVQQPYAGELLLTGDHQRQNAALAA
LCVHKLQAKFSIDNQALSQGLKSAQIEGRFQTQTINNKLVIFDVAHNEAAVQALARELAK
DQQPTLAIFAALKDKNIAHMINAISPQIEQWLLVPLEVHRATDMNFLLNQFSLKETARAC
SSMSAAIERALQQHSCQRIVIFGSFHVVSAALKILK
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
ttgggaggattaaaaactcttgagcaatggcttgcttggcaagaatctctacattctcaa
gaaatagatctcggtttagagcgtattcaaagcgtctactcaagactctttcccgagggc
gttccctttaccactattacggtagctggcaccaatggcaagggctcgaccattgctttg
attgaaagtatttatcaacaaagtatttttacagtggccaaatttacctcgccacatatc
ctaagctataacgagcgctttgttatgaatggcatacaagcaacggatgatcaaatttgt
acagcctttgaggcaatagaacaggttcgtaataacacctcgctaacctattttgagttt
tcaaccttagctgcgctacttatttttgccgagcaaaaaattgatgttgctattttagaa
gttggcttgggtggacgcttagactcaaccaatgtggttgataccgacatggccgttatt
accaatatcgccattgaccatgtagattatttaggtgctacgcgcgagctcattggccat
gaaaaatcaggcattatgcgtgccaatataccttgtatttgtggtgacaccaacccacca
gagtctctcgctaaacacgccaataccgttggcgccttattggaatttgtacagcagcct
tatgctggcgaattattacttactggtgatcatcagcgacaaaacgccgctttggctgca
ctatgcgtccataaacttcaggcaaagtttagcattgataatcaggcactctcccaaggt
cttaaatctgctcaaatcgaagggcgttttcaaactcaaacaatcaataacaagttggtc
atttttgatgttgcgcacaatgaagcggccgttcaagccttggcccgagagctagccaaa
gaccagcagccaacactggccatatttgcagcccttaaagataaaaatattgcgcatatg
attaatgccatctcacctcagattgagcaatggctacttgtgcctttggaagtgcatagg
gcaactgacatgaattttttactcaatcagttctcacttaaagaaactgcccgtgcttgt
agcagtatgagtgcagctattgagcgcgcattgcaacagcactcttgtcaacgtattgtt
atttttggctcttttcacgttgtatcagctgcattaaaaatacttaagtga
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