Thermotoga sp. RQ7: TRQ7_03715
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Entry
TRQ7_03715 CDS
T03669
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
thr
Thermotoga sp. RQ7
Pathway
thr00300
Lysine biosynthesis
thr00550
Peptidoglycan biosynthesis
thr01100
Metabolic pathways
thr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TRQ7_03715
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TRQ7_03715
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TRQ7_03715
Enzymes [BR:
thr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TRQ7_03715
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Beta-prop_EML
Motif
Other DBs
NCBI-ProteinID:
AJG40573
UniProt:
A0A0B5KJK6
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Position
721070..722353
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AA seq
427 aa
AA seq
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MKELLGRRFVLNSKEVKEGDVFVAVKGKRFDGHDFIDEALKRGAHAVIAERAVVHSDRIV
LVKNTVETLAELARLKLNDSPKTIIGITGSNGKTTTKEILYELLKRRRNVFKTPGNMNTE
YGLPLSILNEYGGEEILVLEMAANKKGDIAHLCSIAPPDVAVLLNVGSAHLEFFKSRENI
MEAKLEIVKHSKKDSAVVTFFDDGDLRKKVPVLRENVLFFGTKGGDVVLEDWWYYENSTI
SEYRMFGSSFTIKLPGFWNRGQLLNLAASLCVMKVLGEKVDVLELSNLKAVPGRFNVKEV
EGVRIIDDTYNASPEAFQMAIEALLKFPGRKFAVVGAMKELGEESKKFHEMLGKQLDALD
GVYVFSTEPEAGWIKTRKKVLETDSAEEIARDLYTRVRKGDTVLFKASRAVRIERVLEIF
ERELKKG
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
gtgaaggaactccttggaagaagattcgttttgaactcaaaagaggtaaaggaaggagac
gttttcgttgctgtgaaaggaaaaagattcgacggtcatgatttcatagatgaggctctg
aagcgcggagctcatgctgtcatagcagagagagcagtagtacactcggacagaattgtt
cttgtcaaaaacacggtggaaacgctggcagaacttgcccgcctgaaattgaacgactct
ccgaaaacgataattggaataacgggctcgaacggaaaaacaacaacgaaggaaatactt
tacgaacttctgaagagaagaagaaacgttttcaaaacccccggcaacatgaacacggag
tatggccttcccctttctatactgaacgagtacggtggagaggagatccttgttcttgag
atggccgcaaacaaaaaaggagacatcgcacatctgtgcagcatagcacctcccgacgtg
gccgttttgctgaacgtgggaagcgctcatctggaattcttcaaaagcagggaaaacatc
atggaagccaaactcgagatcgtaaaacattcgaagaaagactccgctgtcgtcacattc
tttgacgatggtgacctgagaaagaaggtgccagttcttagagaaaacgtgttgttcttt
ggaacaaagggtggagatgtcgttctagaggactggtggtactacgaaaactccaccatc
tcagagtaccggatgttcggttcatctttcacgatcaaattaccgggattctggaacaga
ggacaacttctcaatcttgctgcctcactctgtgtcatgaaggtccttggagagaaagtg
gacgttctcgagttatccaatctgaaagctgttccgggaagattcaacgtgaaggaagtg
gagggagtgaggatcatcgacgacacctacaacgccagtccagaagcctttcaaatggcg
atagaagcgcttctcaaattccccggcagaaagttcgccgttgtgggggcgatgaaagag
ctgggggaggaatcgaaaaaatttcatgaaatgctaggaaaacagctcgatgccctggac
ggtgtgtacgtgttttcaactgaacccgaggcagggtggataaaaaccagaaagaaggtg
ctcgaaacagacagtgcagaggagatcgccagagatctctacacgagagtcagaaaagga
gatactgtgctcttcaaagcctccagagcggttagaatagaaagagttctggagatcttc
gaaagggagctgaaaaaaggatga
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