Thalassotalea sp. HSM 43: E2K93_10695
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Entry
E2K93_10695 CDS
T05926
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tht
Thalassotalea sp. HSM 43
Pathway
tht00300
Lysine biosynthesis
tht00550
Peptidoglycan biosynthesis
tht01100
Metabolic pathways
tht01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tht00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
E2K93_10695 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
E2K93_10695 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
E2K93_10695 (murF)
Enzymes [BR:
tht01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
E2K93_10695 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QBY04822
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Position
2481959..2483353
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AA seq
464 aa
AA seq
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MIPLLLNEIADVVGGNILRCEEPETLAITSVSSDSRQLQAGDLFIALKGPNFDGHRFVTQ
ASDIGCSVALVETEQDVDIPQLLVTDCYKAMGKLAAYVKQQVNPKTVAITGSSGKTTVKE
MVAAILSQLGTVLATDGNFNNEIGVPLTLLRLEHQHQYAVIELGANHIGEIAYTTTLTKP
DVAVINNIAAAHLEGFGDLCGVARAKGEIFEGLDETGVALYNQDTPYTHKWQWRLTDKTV
RKFSCVKEADCYCSDVRLNDLGYSSFTLNTYQGNIDITVPVPGRHNVCNAVAAAAIALEF
GATLEQIKSGLGNMAPVKGRLNLISLPDKMTLIDDTYNANVESTKAGVELLGSYAGRRIL
ILGDMAELGEDARRYHQEIGEHALTHHIDNVLTLGVLSQSASQVFNGDGAHFSQRDKLIE
KLAQLLTNEEQTITILVKGSRSARMELVVEDIKQWRNKAEVSSC
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgatcccattactgttaaatgaaatcgccgatgtagtcggtggaaacatattacgttgc
gaggagccggaaactttggccatcaccagtgtcagttccgattcgcgtcaattacaagca
ggcgatctgtttattgctcttaaagggccgaactttgatggtcatcgctttgtcacgcaa
gcgtccgatatcggctgttctgtcgccttggtagagactgagcaagatgtcgacatcccg
caactgttggttaccgattgctacaaagctatgggtaaacttgccgcttatgtaaaacag
caagttaatccaaaaactgtagccatcacaggcagtagcggtaaaaccacggtaaaagaa
atggtggcagcgattttgtcacaacttggcaccgtgttagccactgatggtaacttcaat
aacgaaattggcgtgccgttaaccttattgcgtcttgagcatcagcatcaatatgcggtg
atcgaacttggtgccaatcacattggtgaaatcgcctataccacaacccttactaagcca
gatgtcgccgtcatcaataatattgctgcagctcatttagaaggctttggtgatttatgt
ggtgttgcccgcgccaaaggcgagatatttgaagggctagatgaaaccggggttgcgcta
tataaccaagacacaccatatacccacaagtggcaatggcgcttaaccgataaaaccgta
cgcaaatttagctgcgtaaaagaagccgattgttattgcagtgatgttcgcctcaatgac
cttgggtatagcagtttcaccttgaatacatatcaaggcaatatcgacattaccgtacct
gtaccaggtcgccataatgtatgtaacgccgtcgctgccgcagccatagcgcttgagttt
ggtgcaaccttagagcagatcaaatctggacttggaaatatggcgccggttaaaggccgc
ttaaatctgatcagtctaccggacaaaatgaccctgattgatgatacttataacgccaat
gttgagtcgactaaagccggtgtcgaattgctcggcagttatgcaggtcgccgaatcctg
atactaggcgacatggcagaacttggcgaagatgctcgtcgctatcaccaagaaatcggt
gagcatgcattaacacatcacatagataacgtattaacacttggcgtgctaagtcaaagc
gcatcacaagtgtttaatggcgatggcgcgcatttttcgcagcgagataagctgatcgaa
aaactggcgcaattgcttactaacgaggaacaaacaattactattttggttaagggctca
cgcagtgcccgtatggaacttgtcgttgaagacattaaacaatggcgtaacaaggctgag
gtgagttcatgttag
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