Thalassotalea sp. HSM 43: E2K93_11925
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Entry
E2K93_11925 CDS
T05926
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
tht
Thalassotalea sp. HSM 43
Pathway
tht00230
Purine metabolism
tht01100
Metabolic pathways
tht01110
Biosynthesis of secondary metabolites
Module
tht_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tht00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
E2K93_11925 (purL)
Enzymes [BR:
tht01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
E2K93_11925 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
QBY05050
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Position
complement(2758917..2762837)
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AA seq
1306 aa
AA seq
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MEILRGAPALSDFRINKLLTQCAQLDLPVTEIYAEFMHFSHQSAALSADELSKLEKLLTY
GPSIEEHTPAGTFLLVTPRPGTISPWSSKATDIAHNCGLDKIIRLERGLAFYVQSSAELS
EQQSAQLAALIHDRMMETIFTDTNDVDVLFATAEPGELKSVDILAGGRDALVKANLDLGL
ALAEDEIDYLVENFNALGRNPHDIELYMFAQANSEHCRHKIFNADWTIDGQTQPKSLFKM
IKNTYETNPDNVLSAYKDNAAVMVGSEAGRFFPDPDSKEYAYNVEDINILMKVETHNHPT
AISPFPGAATGSGGEIRDEGATGIGSKPKAGLVGFSVSNLRIPGFEQPWETDFGKPSRIV
TALDIMMEGPLGGAAFNNEFGRPNILGYFRTYEEQVNSFNGEEVRGYHKPIMIAGGLGNI
RGEHVEKGEIVVGAALIALGGPAMNIGLGGGAASSMASGQSDEDLDFASVQRDNPEMERR
CQEVIDRCWQMGDDNPILFIHDVGAGGLSNAFPELVSDGGRGGNFELRNVPNDERSMSPL
EIWCNESQERYVLAVAPERVDEFRALCERERAPFAVVGYATEEEHLTLTDSHFADNEALA
KPIDLPLDVLLGKAPKMHRDVASKTETGKALDLSNVDLADAADRLLRLPTIAEKTFLITI
GDRTVTGMVARDQMVGPWQVPVADCAVTAAALDSYHGEAMSMGERTPVALLNYGASARLA
VAESLTNIASADIGDLNNIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPTLGLTIPVG
KDSMSMKTKWEENGEEKAVTAPLSLVITAFGRVEDIRKTVTPELRTDKGDSRIVAIDLSK
GKNRLGGSCIAQVYKQLGTDTPDVDSAEDLKNFFNLMQHLVRDEKLLAYHDRSDGGLFTA
VAEMAFAGHTGVDIDISKLAGDNLSALFSEELGAVVQIREDDVDAVHAIIEQYGLMECFT
DIGRINNEDMIRFSRDGEEILANSRTYYRTVWAETTFKMQSMRDNPECAEQEHTLKFDTE
DPGLNAELTFDINEDIVADLIAKDADAETNPKVAILREQGVNSHVEMAAAFDRAGFITVD
VHMSDILGERVDLADFNGLVACGGFSYGDVLGAGEGWAKSILFNDKAREMFKTFFHREDT
FSLGVCNGCQMLSNLKEIIPGTKNWPHFVQNRSERFEARFSLVEIQESPSIFFKGMEGSR
MPIAVSHGEGRAEFKSEEAIGAANDSGTVSMRYVDNYGQVTETYPSNPNGSPDGITSLTT
TDGRVTIMMPHPERVFRTVANSWHPDEWLEDSPWVRMFRNARKFIG
NT seq
3921 nt
NT seq
+upstream
nt +downstream
nt
atggaaatcttacgtggcgctcctgcgctttccgatttcagaattaataagctgttaaca
cagtgcgcccagctggatctgccggtaactgagatctacgccgaattcatgcactttagt
catcagtctgcggcattgtctgcggatgagctgagcaaattggaaaagctgctgacctac
ggtccaagcattgaagagcacactcctgctggcacatttttgctagtaactccacgtcca
ggcactatctcaccttggtcatctaaagcgactgacatcgctcacaactgtggcctagat
aaaatcattcgccttgaacgcggtttagcattctacgtgcaatcatcagctgaattaagc
gaacagcaaagtgctcaacttgctgcattgattcacgaccgcatgatggaaaccatcttc
accgacaccaacgacgttgacgtgttatttgcaacagcagaacctggtgaattgaagtca
gttgatattttagccggtggccgagacgccctagttaaagcaaaccttgatttgggtctg
gcgcttgctgaagatgaaattgactacttagtcgagaatttcaacgcccttggccgcaac
ccacacgacattgagttatacatgtttgctcaagcaaactcagaacattgtcgtcacaaa
atttttaacgccgattggacaatcgatggtcagacgcagccgaagtcgctgttcaaaatg
atcaaaaacacctacgaaaccaatcccgacaatgtattaagcgcttacaaagataacgcc
gcggttatggtgggttctgaagccggtcgtttcttcccagatcctgacagcaaagaatac
gcttacaatgttgaagacatcaacattttgatgaaagttgaaacccataaccaccctact
gctatttcaccattcccaggtgctgcaacaggttcaggtggtgagattcgtgatgaaggc
gcaaccggtattggttcaaaaccaaaagcaggtttggttggtttttcggtatcaaactta
cgcatcccaggttttgaacaaccttgggaaacggattttggtaagccaagtcgcatcgta
accgccttagatattatgatggaaggcccacttggtggtgcagcctttaacaacgagttt
ggtcgtccaaacattcttggttacttccgtacttacgaagagcaagttaactcgtttaac
ggtgaagaagttcgtggttaccacaagccaattatgattgcaggtggtttaggtaatatc
cgcggcgagcacgttgaaaaaggtgaaatcgttgttggtgcagcactaatcgcccttggt
ggtccagcaatgaacatcggtttaggtggcggtgcagcatcatcaatggcatcaggccaa
tctgatgaagacctagattttgcttcagtacaacgtgacaacccagaaatggaacgtcgt
tgtcaggaagttatcgatcgctgttggcagatgggtgatgacaacccgattctatttatc
cacgatgttggcgcaggtggtttgtctaacgcattccctgagttggtatctgatggtggc
cgtggtggtaactttgaactgcgcaacgtaccaaacgatgaacgcagcatgtcaccattg
gaaatttggtgtaatgaatcacaagaacgttacgtattagcggtagcaccagagcgtgtt
gacgaattccgcgcattgtgtgagcgtgagcgcgcaccatttgcagtcgttggttacgcc
accgaagaagaacacttaacactaaccgacagccattttgctgacaacgaagcgttagct
aagcctatcgacctgccgttagacgtattactaggtaaagcacctaagatgcaccgagac
gtagcgtcgaaaacagaaacaggtaaagcgcttgatcttagcaacgttgatttagccgat
gcagccgatcgtctattgcgtctacctactatcgcagagaaaaccttcttaatcaccatt
ggtgaccgcacggttaccggtatggttgctcgtgatcaaatggttggtccatggcaggta
cctgtagcagattgtgctgttaccgcagcggctttagacagctaccacggtgaagcgatg
tctatgggtgagcgtacaccggttgcgttacttaactatggcgcgtcagctcgtcttgcc
gtagctgaatcactaaccaatattgccagcgccgacatcggtgacttaaacaacattaag
ttgtctgcaaactggatggccgcagccggtcacccaggtgaagatgcaggtctatacgaa
gcggttaaagccgttggtgaagagttatgtccaaccctaggtttgaccatccctgttggt
aaagactctatgagtatgaaaaccaagtgggaagaaaacggtgaagagaaagcggtaacc
gcacctctatcattggttatcaccgcttttggtcgtgttgaagacattcgcaaaacagtt
actccagagctacgcactgataaaggcgatagccgcattgttgccatcgatttatcaaaa
ggtaagaaccgtttaggtggttcttgtatcgctcaggtatacaagcaattgggtactgac
accccagacgttgatagtgcagaagatctgaaaaacttcttcaacttgatgcaacacttg
gttcgtgatgagaagctacttgcttaccatgaccgttcagacggtggtttattcacagcg
gttgctgaaatggcgtttgccggtcacaccggtgtagatattgacatcagcaaacttgct
ggcgacaacctaagtgcactatttagtgaagagcttggtgcggttgtgcaaatccgtgaa
gacgacgttgacgccgttcacgcgattatcgaacaatacggcttgatggaatgtttcact
gatattggtcgcatcaataacgaagacatgatccgctttagccgcgacggtgaagaaatt
ttggcaaatagccgaacttactaccgtactgtttgggcagagacgaccttcaaaatgcaa
tctatgcgtgataacccagagtgtgcagaacaagaacacaccttgaagtttgatactgaa
gatccaggtctaaatgcagaacttaccttcgacattaacgaagatatcgttgccgaccta
atcgccaaagacgccgacgccgagaccaaccctaaagtggctatcttgcgtgagcaaggt
gttaactcacacgttgaaatggccgccgcatttgaccgtgctggttttatcaccgttgat
gtgcacatgtctgatattcttggcgaacgtgttgatttagccgattttaacggcttagta
gcatgtggtggtttcagttacggtgacgtattgggtgctggtgaaggttgggcaaaatca
atcttgttcaatgacaaagcgcgtgagatgttcaagaccttcttccaccgcgaagacact
ttctcattaggtgtttgtaacggttgtcagatgctgtctaacttgaaagaaatcatccct
ggtactaagaactggccacactttgtgcaaaaccgctcagaacgttttgaagcacgtttc
tcattggttgaaatccaagagtcaccgtctatcttcttcaaaggtatggaaggcagccgc
atgccaatcgctgtttcacacggtgaaggtcgcgcagaattcaaatcagaagaagccatt
ggcgcagccaatgattctggtaccgtatcgatgcgttacgtagacaactacggtcaagtg
actgagacatacccgtcgaacccgaacggttcaccagatggtattacctcactaaccaca
actgacggtcgcgttactatcatgatgcctcaccctgagcgtgtatttagaaccgttgct
aactcatggcaccctgatgaatggttagaagattcaccatgggtacgtatgttccgcaac
gcccgtaagtttattggttaa
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