KEGG   Thalassotalea sp. HSM 43: E2K93_13330
Entry
E2K93_13330       CDS       T05926                                 
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
  KO
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
Organism
tht  Thalassotalea sp. HSM 43
Pathway
tht00790  Folate biosynthesis
tht01100  Metabolic pathways
tht01240  Biosynthesis of cofactors
Module
tht_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:tht00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    E2K93_13330 (folC)
Enzymes [BR:tht01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     E2K93_13330 (folC)
    6.3.2.17  tetrahydrofolate synthase
     E2K93_13330 (folC)
SSDB
Motif
Pfam: Mur_ligase_C Mur_ligase_M Lep_receptor_Ig
Other DBs
NCBI-ProteinID: QBY05297
UniProt: A0A4P7JN35
LinkDB
Position
3068007..3069281
AA seq 424 aa
MNKKTSHSSLANLGEWLFYLESIHATEIDMGLERISKVAKRLDIDLSSSTVITVSGTNGK
GTTCAFLEHALLDMGHSVAVYSSPHIQRFNERLRLNKKLVADQPLIKAFAAIEQARAEIS
LTYYEFTTLAALIICQQTTPEYVLLEVGLGGRLDATNIIDCDIAVITSIDLDHQAFLGDT
RDAIGYEKAGIARANKPLVIGDLQVPASVIEHADRINANCFIRQQHFSVAGEQLLQAWQW
RDQQCQLNELQPAKIPRDNVATALQVLRLLGLPLDATMVNQWINDCQLEGRLQTLKQSPH
VLIDVAHNPHAARYLSRYVKANKKGRVLAVTAMLKDKDIASTLQELFSVVDHWYVAPLHL
PRGADGQMLSDVLTNGNQAVNSFDNVTDAFRIALGHANNNDMVLVFGSFFTLTEINKNLP
ELGL
NT seq 1275 nt   +upstreamnt  +downstreamnt
atgaataaaaaaactagtcattcatccttggccaacctgggtgaatggcttttttatttg
gagtctatccatgccacagaaattgatatggggctggagagaatttccaaggtggccaag
cgtctcgatatagacctatcttcttcaaccgtcattaccgtttcgggcaccaatggcaaa
ggcactacctgcgcctttcttgagcatgccttgctcgatatggggcatagtgttgcggta
tacagttcgccgcatattcagcgttttaacgaacgattacgactaaataaaaagttagtt
gccgatcagccgttgataaaagcgtttgcagcaatagaacaagcgcgcgctgaaatatca
ttgacctactatgagttcaccacgttggcggcattaatcatatgccagcaaacaacgcca
gagtatgtgttactcgaggtcggcttaggtggtcgtttagatgccaccaatatcatcgat
tgtgatattgccgtaatcaccagtattgaccttgatcaccaagcctttcttggtgatacc
cgtgacgccataggctatgaaaaagccggaatcgcccgcgccaataaaccgttagttatt
ggtgatttgcaggtacctgctagcgttatcgaacacgctgatcgcattaatgccaattgc
tttattcgtcagcagcatttctctgttgcaggtgagcagttgctgcaggcgtggcaatgg
cgagatcagcaatgccagttgaacgaactgcaacctgcaaaaatccctcgtgataatgtc
gccaccgcattgcaagtattgcgtttgcttggtttgccattagacgcgactatggtcaat
caatggatcaatgattgtcagctcgaaggccgcttgcaaacattaaagcaatcgccgcat
gtgcttattgatgttgcccacaacccacatgcagcaagatatttaagtcgatatgttaaa
gccaataagaaaggccgagtgttagcggttacggcgatgctgaaggacaaagatatcgcc
tcgaccttgcaggaactgttctctgttgtcgatcactggtatgtggcgccgctgcattta
cctagaggtgcagatggccaaatgttgtctgatgttttaacgaatggcaatcaagctgtg
aatagttttgacaatgtcacagatgcctttagaatagccttaggacacgcaaataataat
gatatggttttggtgtttggatcattttttacactcaccgaaatcaataaaaacctgcct
gaattaggcctatag

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