Thermoflexus hugenholtzii: KNN16_00915
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Entry
KNN16_00915 CDS
T07254
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
thug
Thermoflexus hugenholtzii
Pathway
thug00790
Folate biosynthesis
thug01100
Metabolic pathways
thug01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
thug00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
KNN16_00915
Enzymes [BR:
thug01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
KNN16_00915
6.3.2.17 tetrahydrofolate synthase
KNN16_00915
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
T6SS_Tse3_N
Motif
Other DBs
NCBI-ProteinID:
QWK10847
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Position
168759..170114
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AA seq
451 aa
AA seq
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MSDIETAYAEVLAELFGRADFEARRPRLPEAFRLEPIRSLLERLGDPHRRYAVVHIAGTK
GKGSTAAMVEAILRAAGYRTGLYTSPHLHTMRERIRIDGEPIPPATVVHLFERLRPEIAA
DPALTVFDILTAMGFLAFAEAGVEIAVVEVGLGGRLDSTNVVSPAVCLITALSMDHMEIL
GPTLTHIAFEKAGIIKPGIPVGTAPQAEEAMAVLRRVAAERGAPLLTLDGWRYGPREISP
AGQWGEIHPPEGSGWSVRLPLLGRHQWENAALAVLAALQLRAQGWSLPDAAIPEGLARVR
WPGRFEVLREEPPVVLDGAHNDASAARLAETLMEVFPGRRWGLVFGVSADKDVAAILRPL
RPLVGEVWLTRSRHPRAADPAALVAAAAAFGLPARVRATVATAVEEALASGGPVLVTGSL
FVVAEAREAWAARGGMPMPEVDPLPLRVGGR
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgacatcgagaccgcctacgcggaggtcctggccgagctcttcggccgggcggat
ttcgaggcccgccggccccggctcccggaggctttccgcctggagccgatccgaagcttg
ctggagcggctgggcgacccccaccggcgctacgccgtggtccacatcgcgggcaccaag
ggcaagggctccacggccgcgatggtggaggccatcctgcgggccgccggctaccgcacc
ggcctctacacctccccccatctccacaccatgcgggagcgcatccgcatcgacggggag
cccatcccccctgcgaccgtggttcatctctttgagcgcctccggcccgagatcgcggcg
gatccggccctcacggttttcgacatcctgaccgccatgggtttcctcgcgttcgcggag
gccggggtcgagatcgccgtggtggaggtgggcctgggggggcggctggactccaccaac
gtggtctccccggcggtctgcctgatcaccgccctcagcatggatcacatggagatcctg
ggccctacgctcacccacatcgcctttgagaaggccggcatcatcaagccggggatcccg
gtggggactgcccctcaagccgaggaggcgatggcggtgttgcggcgggtggcggcggag
cgcggcgcccctctcctgaccctggatggatggcggtatggtccgcgggagatctcgccg
gcggggcagtggggggagatccacccgccggagggatcgggctggtcggtgcgccttccc
cttctgggccgccatcagtgggagaacgccgccctggcggtcctggccgccctccagctg
cgggcgcagggctggtcgctccccgatgcggcgatcccggaggggctggcgcgggtgcgc
tggcccggccgattcgaggtgttgcgggaggagcccccggtggtgctggacggggcccac
aacgatgcctccgccgctcgcctggcggagaccctgatggaggtcttcccggggcgccgc
tgggggctggtcttcggggtctcggcggacaaggacgtggcggccatcctgcggccgctg
cgccccctggtcggggaggtctggctgacccgatcccgtcatccccgggcggccgatccc
gcggcgctcgtggccgctgcggcggccttcggcctccccgctcgggtgcgggcgacggtg
gcgacggccgttgaggaggccctggcctccggcgggccggtgctggtcaccggctccctc
ttcgtggtcgccgaggcccgggaggcgtgggcggcgcggggcgggatgcccatgccggag
gtcgatccccttcccctccgggtcgggggtcggtga
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